STRINGSTRING
DsecGM25828 DsecGM25828 DsecGM13236 DsecGM13236 DsecGM15069 DsecGM15069 DsecGM16480 DsecGM16480 DsecGM14921 DsecGM14921 DsecGM23363 DsecGM23363 DsecGM13427 DsecGM13427 DsecGM10377 DsecGM10377 DsecGM11285 DsecGM11285 DsecGM16690 DsecGM16690 DsecGM22147 DsecGM22147 DsecGM18927 DsecGM18927 DsecGM19084 DsecGM19084 DsecGM16076 DsecGM16076 DsecGM16028 DsecGM16028 DsecGM16025 DsecGM16025 DsecGM22866 DsecGM22866 KATNA1-2 KATNA1-2 DsecGM18359 DsecGM18359 DsecGM18655 DsecGM18655 DsecGM17979 DsecGM17979 DsecGM12823 DsecGM12823 DsecGM16253 DsecGM16253 DsecGM18758 DsecGM18758 DsecGM14177 DsecGM14177 DsecGM14179 DsecGM14179 shep shep DsecGM20586 DsecGM20586 DsecGM20601 DsecGM20601 DsecGM20627 DsecGM20627 DsecGM21604 DsecGM21604 DsecGM20728 DsecGM20728 DsecGM21958 DsecGM21958 DsecGM25197 DsecGM25197 DsecGM25192 DsecGM25192 DsecGM26278 DsecGM26278 DsecGM25660 DsecGM25660 DsecGM26195 DsecGM26195 DsecGM26194 DsecGM26194 DsecGM26187 DsecGM26187 DsecGM24530 DsecGM24530 DsecGM26555 DsecGM26555 DsecGM23517 DsecGM23517
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsecGM25828GM25828; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
DsecGM13236GM13236. (1472 aa)
DsecGM15069Ubiquitin carboxyl-terminal hydrolase. (896 aa)
DsecGM16480GM16480. (884 aa)
DsecGM14921GM14921. (974 aa)
DsecGM23363GM23363. (720 aa)
DsecGM13427GM13427; Belongs to the peptidase C2 family. (680 aa)
DsecGM10377GM10377. (696 aa)
DsecGM11285GM11285. (566 aa)
DsecGM16690GM16690. (2936 aa)
DsecGM22147GM22147. (366 aa)
DsecGM18927GM18927. (505 aa)
DsecGM19084GM19084; Belongs to the SKP1 family. (162 aa)
DsecGM16076GM16076. (337 aa)
DsecGM16028Phosphatidylinositol 3-kinase catalytic subunit type 3. (949 aa)
DsecGM16025GM16025; Belongs to the peptidase C14A family. (323 aa)
DsecGM22866GM22866; Belongs to the AAA ATPase family. (442 aa)
KATNA1-2Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (711 aa)
DsecGM18359Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (747 aa)
DsecGM18655Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2549 aa)
DsecGM17979Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
DsecGM12823GM12823; Belongs to the peptidase C14A family. (343 aa)
DsecGM16253GM16253. (1071 aa)
DsecGM18758GM18758. (692 aa)
DsecGM14177GM14177. (135 aa)
DsecGM14179GM14179. (900 aa)
shepProtein alan shepard; Has a role in the perception of gravity. (579 aa)
DsecGM20586GM20586; Belongs to the ubiquitin-activating E1 family. (1191 aa)
DsecGM20601GM20601. (517 aa)
DsecGM20627GM20627. (226 aa)
DsecGM21604GM21604. (642 aa)
DsecGM20728Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (210 aa)
DsecGM21958GM21958; Belongs to the peptidase C2 family. (843 aa)
DsecGM25197GM25197; Belongs to the peptidase C14A family. (449 aa)
DsecGM25192GM25192; Belongs to the peptidase C2 family. (925 aa)
DsecGM26278GM26278. (1345 aa)
DsecGM25660GM25660. (408 aa)
DsecGM26195GM26195. (793 aa)
DsecGM26194GM26194. (2934 aa)
DsecGM26187GM26187. (682 aa)
DsecGM24530GM24530. (1821 aa)
DsecGM26555Structural maintenance of chromosomes protein. (1194 aa)
DsecGM23517GM23517. (422 aa)
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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