(51 nodes) Negative regulation of hippo signaling network (Drosophila sechellia)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsecGM16909	GM16909. (591 aa)
	DsecGM16085	GM16085. (214 aa)
	DsecGM16553	GM16553. (505 aa)
	DsecGM13293	GM13293. (357 aa)
	DsecGM11050	GM11050. (240 aa)
	DsecGM11725	GM11725. (294 aa)
	DsecGM13227	GM13227; Belongs to the peptidase C19 family. (1129 aa)
	DsecGM23237	GM23237. (1404 aa)
	DsecGM26733	GM26733. (889 aa)
	DsecGM13011	GM13011. (563 aa)
	DsecGM15099	GM15099. (510 aa)
	DsecGM16425	GM16425. (200 aa)
	DsecGM11599	GM11599. (334 aa)
	DsecGM11579	GM11579; Belongs to the protein kinase superfamily. (337 aa)
	DsecGM17582	GM17582. (718 aa)
	DsecGM16849	E3 ubiquitin-protein ligase. (949 aa)
	DsecGM16650	GM16650. (2943 aa)
	DsecGM18924	GM18924. (1329 aa)
	DsecGM19084	GM19084; Belongs to the SKP1 family. (162 aa)
	DsecGM22846	GM22846. (607 aa)
	DsecGM18685	GM18685. (1621 aa)
	DsecGM16990	GM16990; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1234 aa)
	DsecGM16687	GM16687. (749 aa)
	DsecGM16609	Serine/threonine-protein phosphatase. (309 aa)
	DsecGM13731	GM13731. (315 aa)
	DsecGM15179	Mitogen-activated protein kinase. (365 aa)
	DsecGM11060	GM11060. (1875 aa)
	DsecGM14161	GM14161. (184 aa)
	DsecGM14399	GM14399. (1058 aa)
	DsecGM14344	GM14344. (1414 aa)
	DsecGM14625	GM14625; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
	DsecGM14058	GM14058. (935 aa)
	DsecGM20105	GM20105. (1726 aa)
	DsecGM20106	GM20106. (4490 aa)
	DsecGM20163	GM20163. (131 aa)
	DsecGM20164	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (954 aa)
	DsecGM20989	GM20989; Belongs to the cullin family. (774 aa)
	DsecGM20762	GM20762; Belongs to the protein kinase superfamily. Tyr protein kinase family. (919 aa)
	DsecGM20233	GM20233. (64 aa)
	DsecGM20234	GM20234. (1820 aa)
	DsecGM20860	GM20860. (223 aa)
	DsecGM21966	Non-specific serine/threonine protein kinase. (1192 aa)
	DsecGM21909	GM21909. (766 aa)
	DsecGM21908	GM21908. (703 aa)
	DsecGM21814	GM21814. (355 aa)
	DsecGM21807	GM21807. (1060 aa)
	DsecGM21803	GM21803. (838 aa)
	DsecGM19973	GM19973. (1704 aa)
	DsecGM24284	Non-specific serine/threonine protein kinase. (530 aa)
	DsecGM24647	Non-specific serine/threonine protein kinase. (1854 aa)
	DsecGM23592	GM23592. (806 aa)

Your Current Organism:

Drosophila sechellia

NCBI taxonomy Id: 7238
Other names: D. sechellia

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsecGM11050	DsecGM11579	B4INJ6	B4IGI2	GM11050.	GM11579; Belongs to the protein kinase superfamily.	0.696
DsecGM11050	DsecGM16909	B4INJ6	B4HYJ6	GM11050.	GM16909.	0.488
DsecGM11050	DsecGM19084	B4INJ6	B4I948	GM11050.	GM19084; Belongs to the SKP1 family.	0.994
DsecGM11050	DsecGM20989	B4INJ6	B4HR93	GM11050.	GM20989; Belongs to the cullin family.	0.991
DsecGM11050	DsecGM21803	B4INJ6	B4HMX0	GM11050.	GM21803.	0.431
DsecGM11050	DsecGM21807	B4INJ6	B4HMY0	GM11050.	GM21807.	0.574
DsecGM11050	DsecGM23237	B4INJ6	B4IL75	GM11050.	GM23237.	0.943
DsecGM11050	DsecGM24284	B4INJ6	B4HLD8	GM11050.	Non-specific serine/threonine protein kinase.	0.713
DsecGM11060	DsecGM16849	B4HX55	B4IDF3	GM11060.	E3 ubiquitin-protein ligase.	0.432
DsecGM11060	DsecGM20105	B4HX55	B4HSH4	GM11060.	GM20105.	0.424
DsecGM11060	DsecGM20106	B4HX55	B4HSH2	GM11060.	GM20106.	0.424
DsecGM11060	DsecGM20163	B4HX55	B4HRS6	GM11060.	GM20163.	0.583
DsecGM11060	DsecGM20164	B4HX55	B4HRS5	GM11060.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.783
DsecGM11060	DsecGM21807	B4HX55	B4HMY0	GM11060.	GM21807.	0.432
DsecGM11060	DsecGM24284	B4HX55	B4HLD8	GM11060.	Non-specific serine/threonine protein kinase.	0.401
DsecGM11060	DsecGM24647	B4HX55	B4HG27	GM11060.	Non-specific serine/threonine protein kinase.	0.815
DsecGM11579	DsecGM11050	B4IGI2	B4INJ6	GM11579; Belongs to the protein kinase superfamily.	GM11050.	0.696
DsecGM11579	DsecGM15099	B4IGI2	B4IKK5	GM11579; Belongs to the protein kinase superfamily.	GM15099.	0.696
DsecGM11579	DsecGM16609	B4IGI2	B4HYB2	GM11579; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.519
DsecGM11579	DsecGM16909	B4IGI2	B4HYJ6	GM11579; Belongs to the protein kinase superfamily.	GM16909.	0.471