STRINGSTRING
DsecGM16366 DsecGM16366 DsecCdc37 DsecCdc37 DsecGM24789 DsecGM24789 DsecGM24216 DsecGM24216 DsecGM26415 DsecGM26415 DsecGM26416 DsecGM26416 DsecGM24726 DsecGM24726 DsecGM24703 DsecGM24703 hh hh Dsecpnt Dsecpnt DsecGM23574 DsecGM23574 DsecGM23572 DsecGM23572 DsecGM25914 DsecGM25914 DsecGM23547 DsecGM23547 spas spas DsecGM26614 DsecGM26614 DsecGM24586 DsecGM24586 DsecGM25436 DsecGM25436 DsecGM25464 DsecGM25464 DsecGM24530 DsecGM24530 DsecGM23939 DsecGM23939 DsecGM26187 DsecGM26187 DsecGM25091 DsecGM25091 DsecGM25659 DsecGM25659 Ras85D Ras85D DsecGM25145 DsecGM25145 DsecGM23732 DsecGM23732 DsecGM24835 DsecGM24835 DsecGM25193 DsecGM25193 DsecGM21230 DsecGM21230 DsecGM21303 DsecGM21303 DsecGM20860 DsecGM20860 DsecGM20272 DsecGM20272 DsecGM20940 DsecGM20940 DsecGM20248 DsecGM20248 DsecGM20247 DsecGM20247 DsecGM20989 DsecGM20989 DsecGM20707 DsecGM20707 DsecGM21585 DsecGM21585 DsecGM20164 DsecGM20164 DsecGM20163 DsecGM20163 DsecGM21604 DsecGM21604 DsecGM21084 DsecGM21084 DsecGM20108 DsecGM20108 Lis-1 Lis-1 DsecGM21728 DsecGM21728 DsecHsp83 DsecHsp83 DsecGM14583 DsecGM14583 DsecGM13947 DsecGM13947 DsecGM13945 DsecGM13945 DsecGM14715 DsecGM14715 DsecDnaJ-1 DsecDnaJ-1 DsecGM13901 DsecGM13901 DsecGM14366 DsecGM14366 DsecGM14225 DsecGM14225 DsecGM11912 DsecGM11912 DsecGM15214 DsecGM15214 DsecGM16687 DsecGM16687 DsecGM12386 DsecGM12386 DsecGM12906 DsecGM12906 DsecGM12929 DsecGM12929 DsecGM12930 DsecGM12930 DsecGM12360 DsecGM12360 DsecGM12359 DsecGM12359 DsecGM12709 DsecGM12709 DsecGM17979 DsecGM17979 DsecGM18293 DsecGM18293 DsecGM18275 DsecGM18275 DsecGM18367 DsecGM18367 DsecGM18396 DsecGM18396 DsecGM11002 DsecGM11002 DsecGM10815 DsecGM10815 DsecGM10828 DsecGM10828 KATNA1-2 KATNA1-2 DsecGM10913 DsecGM10913 DsecGM17128 DsecGM17128 DsecGM17376 DsecGM17376 DsecGM22846 DsecGM22846 DsecGM22833 DsecGM22833 DsecGM22805 DsecGM22805 DsecGM22804 DsecGM22804 DsecGM22706 DsecGM22706 DsecGM15810 DsecGM15810 DsecGM15661 DsecGM15661 DsecGM15999 DsecGM15999 DsecGM15489 DsecGM15489 DsecGM16076 DsecGM16076 DsecGM19051 DsecGM19051 DsecGM19082 DsecGM19082 DsecGM18987 DsecGM18987 DsecGM19224 DsecGM19224 DsecGM18876 DsecGM18876 DsecGM18875 DsecGM18875 DsecGM19233 DsecGM19233 DsecGM19264 DsecGM19264 DsecGM19268 DsecGM19268 DsecGM22131 DsecGM22131 DsecGM22073 DsecGM22073 DsecGM15291 DsecGM15291 DsecGM10294 DsecGM10294 DsecGM10206 DsecGM10206 DsecGM10297 DsecGM10297 DsecGM16725 DsecGM16725 DsecGM16726 DsecGM16726 DsecGM16816 DsecGM16816 DsecGM16585 DsecGM16585 DsecGM16579 DsecGM16579 DsecGM11474 DsecGM11474 DsecGM26763 DsecGM26763 DsecGM26108 DsecGM26108 DsecGM26892 DsecGM26892 DsecGM10042 DsecGM10042 DsecGM13352 DsecGM13352 DsecGM13302 DsecGM13302 DsecGM13449 DsecGM13449 DsecGM23277 DsecGM23277 DsecGM23399 DsecGM23399 DsecGM17593 DsecGM17593 DsecGM17592 DsecGM17592 DsecGM16480 DsecGM16480 DsecGM23175 DsecGM23175 DsecGM17739 DsecGM17739 DsecGM17828 DsecGM17828 DsecGM21290 DsecGM21290 DsecGM21279 DsecGM21279 DsecGM21160 DsecGM21160 DsecGM15089 DsecGM15089 DsecGM15099 DsecGM15099 DsecGM13017 DsecGM13017 DsecGM13016 DsecGM13016 DsecGM13010 DsecGM13010 DsecGM11208 DsecGM11208 DsecGM11959 DsecGM11959 DsecGM23238 DsecGM23238 DsecGM23237 DsecGM23237 DsecGM22478 DsecGM22478 DsecGM16932 DsecGM16932 DsecGM11050 DsecGM11050 DsecGM23095 DsecGM23095 DsecGM11118 DsecGM11118
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsecGM16366Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (468 aa)
DsecCdc37Cdc37. (389 aa)
DsecGM24789GM24789. (792 aa)
DsecGM24216GM24216; Belongs to the tropomyosin family. (284 aa)
DsecGM26415GM26415; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
DsecGM26416GM26416. (160 aa)
DsecGM24726Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (586 aa)
DsecGM24703GM24703; Belongs to the cyclin family. (490 aa)
hhProtein hedgehog C-product; Intercellular signal essential for a variety of patterning events during development. Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks. Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc. In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu) (By similarity). The hedgehog protein C-product, which mediates the autocatalytic activity, [...] (465 aa)
DsecpntPnt. (627 aa)
DsecGM23574GM23574. (243 aa)
DsecGM23572GM23572. (246 aa)
DsecGM25914GM25914. (992 aa)
DsecGM23547GM23547. (332 aa)
spasSpastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (758 aa)
DsecGM26614GM26614. (626 aa)
DsecGM24586GM24586. (531 aa)
DsecGM25436GM25436. (1265 aa)
DsecGM25464GM25464; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
DsecGM24530GM24530. (1821 aa)
DsecGM23939GM23939. (1765 aa)
DsecGM26187GM26187. (682 aa)
DsecGM25091GM25091. (1396 aa)
DsecGM25659GM25659. (332 aa)
Ras85DRas-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
DsecGM25145Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (203 aa)
DsecGM23732LIM domain-containing protein. (348 aa)
DsecGM24835GM24835. (1159 aa)
DsecGM25193GM25193. (338 aa)
DsecGM21230GM21230; Belongs to the G-protein coupled receptor 2 family. (3575 aa)
DsecGM21303GM21303. (398 aa)
DsecGM20860GM20860. (223 aa)
DsecGM20272GM20272. (578 aa)
DsecGM20940GM20940. (1302 aa)
DsecGM20248GM20248. (1197 aa)
DsecGM20247GM20247. (6453 aa)
DsecGM20989GM20989; Belongs to the cullin family. (774 aa)
DsecGM20707GM20707. (435 aa)
DsecGM21585GM21585. (228 aa)
DsecGM20164Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (954 aa)
DsecGM20163GM20163. (131 aa)
DsecGM21604GM21604. (642 aa)
DsecGM21084Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (617 aa)
DsecGM20108GM20108. (373 aa)
Lis-1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (411 aa)
DsecGM21728GM21728. (1007 aa)
DsecHsp83Hsp83. (717 aa)
DsecGM14583GM14583. (750 aa)
DsecGM13947GM13947. (2194 aa)
DsecGM13945GM13945. (1237 aa)
DsecGM14715GM14715. (924 aa)
DsecDnaJ-1DnaJ-1. (337 aa)
DsecGM13901GM13901. (391 aa)
DsecGM14366GM14366. (469 aa)
DsecGM14225GM14225. (192 aa)
DsecGM11912Mitogen-activated protein kinase. (372 aa)
DsecGM15214GM15214. (1653 aa)
DsecGM16687GM16687. (749 aa)
DsecGM12386GM12386. (506 aa)
DsecGM12906GM12906. (89 aa)
DsecGM12929GM12929. (243 aa)
DsecGM12930GM12930. (105 aa)
DsecGM12360GM12360. (159 aa)
DsecGM12359Dynein light chain. (89 aa)
DsecGM12709GM12709. (2778 aa)
DsecGM17979Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
DsecGM18293GM18293. (1996 aa)
DsecGM18275GM18275. (391 aa)
DsecGM18367GM18367. (586 aa)
DsecGM18396GM18396. (135 aa)
DsecGM11002GM11002. (2097 aa)
DsecGM10815GM10815. (182 aa)
DsecGM10828Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (762 aa)
KATNA1-2Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (711 aa)
DsecGM10913GM10913. (333 aa)
DsecGM17128GM17128. (677 aa)
DsecGM17376GM17376. (156 aa)
DsecGM22846GM22846. (607 aa)
DsecGM22833RBR-type E3 ubiquitin transferase. (504 aa)
DsecGM22805Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (303 aa)
DsecGM22804GM22804. (111 aa)
DsecGM22706GM22706. (1560 aa)
DsecGM15810GM15810. (129 aa)
DsecGM15661GM15661. (758 aa)
DsecGM15999GM15999. (549 aa)
DsecGM15489GM15489. (133 aa)
DsecGM16076GM16076. (337 aa)
DsecGM19051GM19051. (1619 aa)
DsecGM19082GM19082. (108 aa)
DsecGM18987GM18987. (1410 aa)
DsecGM19224GM19224. (739 aa)
DsecGM18876GM18876. (1751 aa)
DsecGM18875GM18875. (639 aa)
DsecGM19233GM19233. (346 aa)
DsecGM19264GM19264. (2671 aa)
DsecGM19268GM19268. (715 aa)
DsecGM22131GM22131. (386 aa)
DsecGM22073GM22073; Belongs to the small GTPase superfamily. Arf family. (182 aa)
DsecGM15291GM15291. (607 aa)
DsecGM10294GM10294. (205 aa)
DsecGM10206GM10206. (195 aa)
DsecGM10297GM10297. (221 aa)
DsecGM16725GM16725. (166 aa)
DsecGM16726GM16726. (123 aa)
DsecGM16816Dynein light chain. (89 aa)
DsecGM16585GM16585. (248 aa)
DsecGM16579GM16579. (611 aa)
DsecGM11474GM11474. (601 aa)
DsecGM26763GM26763. (816 aa)
DsecGM26108GM26108. (1032 aa)
DsecGM26892GM26892. (211 aa)
DsecGM10042GM10042. (385 aa)
DsecGM13352GM13352. (335 aa)
DsecGM13302GM13302. (1105 aa)
DsecGM13449Non-specific serine/threonine protein kinase. (636 aa)
DsecGM23277GM23277. (1100 aa)
DsecGM23399GM23399. (773 aa)
DsecGM17593GM17593. (62 aa)
DsecGM17592GM17592. (301 aa)
DsecGM16480GM16480. (884 aa)
DsecGM23175GM23175; Belongs to the PI3/PI4-kinase family. (1088 aa)
DsecGM17739GM17739. (441 aa)
DsecGM17828GM17828. (538 aa)
DsecGM21290GM21290. (266 aa)
DsecGM21279GM21279. (472 aa)
DsecGM21160GM21160. (631 aa)
DsecGM15089GM15089. (205 aa)
DsecGM15099GM15099. (510 aa)
DsecGM13017GM13017. (178 aa)
DsecGM13016GM13016. (1364 aa)
DsecGM13010GM13010. (948 aa)
DsecGM11208Mothers against decapentaplegic homolog. (486 aa)
DsecGM11959GM11959. (799 aa)
DsecGM23238GM23238. (2004 aa)
DsecGM23237GM23237. (1404 aa)
DsecGM22478GM22478. (816 aa)
DsecGM16932Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (340 aa)
DsecGM11050GM11050. (240 aa)
DsecGM23095GM23095. (182 aa)
DsecGM11118GM11118. (211 aa)
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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