STRINGSTRING
chico chico DsecGM25186 DsecGM25186 DsecGM24284 DsecGM24284 DsecGM21937 DsecGM21937 DsecGM20273 DsecGM20273 DsecGM20999 DsecGM20999 DsecGM14542 DsecGM14542 DsecGM13898 DsecGM13898 DsecGM13894 DsecGM13894 DsecGM14309 DsecGM14309 DsecGM25822 DsecGM25822 DsecGM25824 DsecGM25824 DsecGM25825 DsecGM25825 DsecGM23508 DsecGM23508 DsecGM24036 DsecGM24036 DsecGM23923 DsecGM23923 DsecGM25540 DsecGM25540 Ras85D Ras85D DsecGM23095 DsecGM23095 DsecGM16553 DsecGM16553 DsecGM16932 DsecGM16932 DsecGM13622 DsecGM13622 DsecGM23175 DsecGM23175 DsecGM11599 DsecGM11599 DsecGM10094 DsecGM10094 DsecGM10089 DsecGM10089 DsecGM11356 DsecGM11356 DsecGM22222 DsecGM22222 DsecGM19268 DsecGM19268 DsecGM22753 DsecGM22753 DsecGM22754 DsecGM22754 DsecGM17386 DsecGM17386 DsecGM10494 DsecGM10494 DsecGM10815 DsecGM10815 DsecGM10629 DsecGM10629 DsecGM11002 DsecGM11002 DsecGM18321 DsecGM18321 DsecGM18685 DsecGM18685 DsecGM12941 DsecGM12941 DsecGM13122 DsecGM13122 DsecGM13624 DsecGM13624 DsecGM13633 DsecGM13633 DsecGM13635 DsecGM13635 DsecGM15254 DsecGM15254 DsecGM15179 DsecGM15179
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chicoInsulin receptor substrate 1; Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. May mediate the control of various cellular processes by insulin-like peptides. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains. Involved in control of cell proliferation, cell size, and body and organ growth throughout development. Also has a role in a signaling pathway controlling the physiological response required to endure periods of low nutrient conditions. Insulin/insulin-like growth factor (IGF) signal [...] (964 aa)
DsecGM25186Preproinsulin-like peptide 2. (137 aa)
DsecGM24284Non-specific serine/threonine protein kinase. (530 aa)
DsecGM21937Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (947 aa)
DsecGM20273GM20273. (211 aa)
DsecGM20999GM20999; Belongs to the WD repeat SEC13 family. (354 aa)
DsecGM14542GM14542. (1381 aa)
DsecGM13898GM13898. (528 aa)
DsecGM13894Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (490 aa)
DsecGM14309GM14309. (736 aa)
DsecGM25822GM25822. (212 aa)
DsecGM25824GM25824. (952 aa)
DsecGM25825GM25825. (2646 aa)
DsecGM23508Mitogen-activated protein kinase. (366 aa)
DsecGM24036GM24036; Belongs to the fatty acid desaturase type 1 family. (402 aa)
DsecGM23923GM23923; Belongs to the TCTP family. (172 aa)
DsecGM25540GM25540. (2135 aa)
Ras85DRas-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
DsecGM23095GM23095. (182 aa)
DsecGM16553GM16553. (505 aa)
DsecGM16932Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (340 aa)
DsecGM13622Nipped-B protein. (2078 aa)
DsecGM23175GM23175; Belongs to the PI3/PI4-kinase family. (1088 aa)
DsecGM11599GM11599. (334 aa)
DsecGM10094GM10094. (454 aa)
DsecGM10089GM10089. (681 aa)
DsecGM11356GM11356. (313 aa)
DsecGM22222GM22222. (439 aa)
DsecGM19268GM19268. (715 aa)
DsecGM22753GM22753. (717 aa)
DsecGM22754GM22754. (952 aa)
DsecGM17386GM17386. (280 aa)
DsecGM10494GM10494. (320 aa)
DsecGM10815GM10815. (182 aa)
DsecGM10629GM10629. (959 aa)
DsecGM11002GM11002. (2097 aa)
DsecGM18321GM18321. (867 aa)
DsecGM18685GM18685. (1621 aa)
DsecGM12941GM12941. (1589 aa)
DsecGM13122Receptor protein-tyrosine kinase. (1509 aa)
DsecGM13624GM13624. (473 aa)
DsecGM13633GM13633; Belongs to the PDGF/VEGF growth factor family. (477 aa)
DsecGM13635GM13635. (405 aa)
DsecGM15254GM15254. (1580 aa)
DsecGM15179Mitogen-activated protein kinase. (365 aa)
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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