(14 nodes) SMAD protein signal transduction network (Drosophila sechellia)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsecGM11208	Mothers against decapentaplegic homolog. (486 aa)
	DsecGM13010	GM13010. (948 aa)
	DsecGM16436	Mothers against decapentaplegic homolog. (769 aa)
	DsecGM26771	GM26771. (598 aa)
	DsecGM26775	GM26775. (700 aa)
	DsecGM15202	Mothers against decapentaplegic homolog. (569 aa)
	DsecGM16052	GM16052. (455 aa)
	DsecGM16994	GM16994. (400 aa)
	DsecGM18164	Mothers against decapentaplegic homolog. (545 aa)
	DsecGM18367	GM18367. (586 aa)
	DsecGM18343	GM18343. (583 aa)
	DsecGM18031	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (563 aa)
	DsecGM14019	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (903 aa)
	DsecGM21084	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (617 aa)

Your Current Organism:

Drosophila sechellia

NCBI taxonomy Id: 7238
Other names: D. sechellia

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsecGM11208	DsecGM13010	B4IKX2	B4IKR2	Mothers against decapentaplegic homolog.	GM13010.	0.836
DsecGM11208	DsecGM14019	B4IKX2	B4HTZ0	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.868
DsecGM11208	DsecGM15202	B4IKX2	B4IBM7	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.508
DsecGM11208	DsecGM16052	B4IKX2	B4I8U4	Mothers against decapentaplegic homolog.	GM16052.	0.593
DsecGM11208	DsecGM16436	B4IKX2	B4IJ10	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.999
DsecGM11208	DsecGM16994	B4IKX2	B4I5Z1	Mothers against decapentaplegic homolog.	GM16994.	0.593
DsecGM11208	DsecGM18031	B4IKX2	B4I1E4	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.800
DsecGM11208	DsecGM18343	B4IKX2	B4I2K9	Mothers against decapentaplegic homolog.	GM18343.	0.799
DsecGM11208	DsecGM18367	B4IKX2	B4I2Q6	Mothers against decapentaplegic homolog.	GM18367.	0.621
DsecGM11208	DsecGM21084	B4IKX2	B4HSC7	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.993
DsecGM11208	DsecGM26771	B4IKX2	B4IIY4	Mothers against decapentaplegic homolog.	GM26771.	0.755
DsecGM11208	DsecGM26775	B4IKX2	B4IIX7	Mothers against decapentaplegic homolog.	GM26775.	0.595
DsecGM13010	DsecGM11208	B4IKR2	B4IKX2	GM13010.	Mothers against decapentaplegic homolog.	0.836
DsecGM13010	DsecGM14019	B4IKR2	B4HTZ0	GM13010.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.712
DsecGM13010	DsecGM15202	B4IKR2	B4IBM7	GM13010.	Mothers against decapentaplegic homolog.	0.475
DsecGM13010	DsecGM16436	B4IKR2	B4IJ10	GM13010.	Mothers against decapentaplegic homolog.	0.606
DsecGM13010	DsecGM18031	B4IKR2	B4I1E4	GM13010.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.977
DsecGM13010	DsecGM18164	B4IKR2	B4I2W3	GM13010.	Mothers against decapentaplegic homolog.	0.427
DsecGM13010	DsecGM21084	B4IKR2	B4HSC7	GM13010.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.951
DsecGM14019	DsecGM11208	B4HTZ0	B4IKX2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.868