(17 nodes) Sm domain, eukaryotic/archaea-type network (Drosophila sechellia)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsecGM25341	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	DsecGM13382	Small nuclear ribonucleoprotein G. (76 aa)
	DsecGM26694	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (61 aa)
	DsecGM15790	GM15790; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (79 aa)
	DsecGM17159	GM17159. (110 aa)
	DsecGM10560	Small nuclear ribonucleoprotein Sm D2. (119 aa)
	DsecGM18377	GM18377. (121 aa)
	DsecGM11667	Small nuclear ribonucleoprotein-associated protein. (199 aa)
	DsecGM11687	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (140 aa)
	DsecGM14170	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
	DsecGM15742	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (137 aa)
	DsecGM14749	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	DsecGM20576	GM20576. (256 aa)
	DsecGM20378	GM20378; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (88 aa)
	DsecGM20491	GM20491. (141 aa)
	DsecGM21338	Small nuclear ribonucleoprotein Sm D3. (151 aa)
	DsecGM24635	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (124 aa)

Your Current Organism:

Drosophila sechellia

NCBI taxonomy Id: 7238
Other names: D. sechellia

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsecGM10560	DsecGM11667	B4I4E8	B4HWP3	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein-associated protein.	0.999
DsecGM10560	DsecGM11687	B4I4E8	B4HWN4	Small nuclear ribonucleoprotein Sm D2.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.990
DsecGM10560	DsecGM13382	B4I4E8	B4IEQ4	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein G.	0.999
DsecGM10560	DsecGM14170	B4I4E8	B4HW01	Small nuclear ribonucleoprotein Sm D2.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.990
DsecGM10560	DsecGM14749	B4I4E8	B4HUN7	Small nuclear ribonucleoprotein Sm D2.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.954
DsecGM10560	DsecGM15742	B4I4E8	B4I7L2	Small nuclear ribonucleoprotein Sm D2.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.672
DsecGM10560	DsecGM15790	B4I4E8	B4I7G9	Small nuclear ribonucleoprotein Sm D2.	GM15790; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.992
DsecGM10560	DsecGM17159	B4I4E8	B4I543	Small nuclear ribonucleoprotein Sm D2.	GM17159.	0.995
DsecGM10560	DsecGM18377	B4I4E8	B4I2S6	Small nuclear ribonucleoprotein Sm D2.	GM18377.	0.978
DsecGM10560	DsecGM20378	B4I4E8	B4HP62	Small nuclear ribonucleoprotein Sm D2.	GM20378; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.999
DsecGM10560	DsecGM20491	B4I4E8	B4HN08	Small nuclear ribonucleoprotein Sm D2.	GM20491.	0.997
DsecGM10560	DsecGM20576	B4I4E8	B4HT49	Small nuclear ribonucleoprotein Sm D2.	GM20576.	0.867
DsecGM10560	DsecGM21338	B4I4E8	B4HP55	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein Sm D3.	0.999
DsecGM10560	DsecGM24635	B4I4E8	B4HG52	Small nuclear ribonucleoprotein Sm D2.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.999
DsecGM10560	DsecGM25341	B4I4E8	B4HFL6	Small nuclear ribonucleoprotein Sm D2.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.998
DsecGM10560	DsecGM26694	B4I4E8	B4IQP9	Small nuclear ribonucleoprotein Sm D2.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.954
DsecGM11667	DsecGM10560	B4HWP3	B4I4E8	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein Sm D2.	0.999
DsecGM11667	DsecGM11687	B4HWP3	B4HWN4	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.989
DsecGM11667	DsecGM13382	B4HWP3	B4IEQ4	Small nuclear ribonucleoprotein-associated protein.	Small nuclear ribonucleoprotein G.	0.999
DsecGM11667	DsecGM14170	B4HWP3	B4HW01	Small nuclear ribonucleoprotein-associated protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.963