(95 nodes) GTP hydrolysis and joining of the 60S ribosomal subunit network (Drosophila sechellia)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsecGM24605	GM24605. (216 aa)
	DsecGM24197	GM24197. (216 aa)
	DsecGM25815	GM25815; Belongs to the universal ribosomal protein uS7 family. (230 aa)
	DsecGM25301	GM25301. (217 aa)
	DsecGM26502	GM26502; Belongs to the universal ribosomal protein uS3 family. (246 aa)
	DsecGM23526	GM23526. (155 aa)
	DsecGM25348	GM25348. (212 aa)
	DsecGM25391	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (139 aa)
	DsecGM25394	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (261 aa)
	DsecGM23925	GM23925; Belongs to the universal ribosomal protein uL3 family. (611 aa)
	DsecGM26117	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (117 aa)
	DsecGM25586	GM25586. (153 aa)
	DsecGM23839	GM23839. (56 aa)
	DsecGM25070	GM25070. (153 aa)
	DsecGM26264	GM26264. (164 aa)
	DsecGM24873	GM24873. (131 aa)
	DsecGM24860	GM24860; Belongs to the universal ribosomal protein uS4 family. (195 aa)
	DsecGM19972	60S ribosomal protein L18a; Belongs to the eukaryotic ribosomal protein eL20 family. (177 aa)
	DsecGM20375	GM20375; Belongs to the universal ribosomal protein uS17 family. (196 aa)
	DsecGM21960	GM21960; Belongs to the universal ribosomal protein uL5 family. (204 aa)
	DsecGM20223	GM20223; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	DsecGM21136	GM21136. (124 aa)
	DsecGM20051	GM20051; Belongs to the universal ribosomal protein uS19 family. (148 aa)
	DsecGM21711	GM21711; Belongs to the eukaryotic ribosomal protein P1/P2 family. (113 aa)
	DsecGM14495	GM14495. (256 aa)
	DsecGM14063	GM14063. (144 aa)
	DsecGM14051	GM14051. (1056 aa)
	DsecGM13785	GM13785. (188 aa)
	DsecGM14186	GM14186; Belongs to the universal ribosomal protein uL23 family. (70 aa)
	DsecGM14185	GM14185. (139 aa)
	DsecGM12203	GM12203; Belongs to the universal ribosomal protein uS5 family. (267 aa)
	DsecGM17848	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (218 aa)
	DsecGM17982	GM17982. (252 aa)
	DsecGM11214	GM11214. (190 aa)
	DsecGM13202	GM13202; Belongs to the eukaryotic ribosomal protein eL42 family. (104 aa)
	DsecGM13013	GM13013; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	DsecGM12832	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	DsecGM12191	GM12191. (136 aa)
	DsecGM12186	GM12186. (134 aa)
	DsecGM12166	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	DsecGM12554	GM12554; Belongs to the universal ribosomal protein uL22 family. (186 aa)
	DsecGM12569	GM12569. (271 aa)
	DsecGM12424	GM12424. (123 aa)
	DsecGM18527	GM18527. (92 aa)
	DsecGM18298	GM18298; Belongs to the universal ribosomal protein uL11 family. (165 aa)
	DsecGM18276	GM18276. (51 aa)
	RpS21	40S ribosomal protein S21; May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva (By similarity). (83 aa)
	DsecGM18458	GM18458. (128 aa)
	DsecGM18088	GM18088; Belongs to the universal ribosomal protein uL15 family. (149 aa)
	DsecGM10633	GM10633. (157 aa)
	DsecGM10821	GM10821; Belongs to the universal ribosomal protein uL13 family. (205 aa)
	DsecGM17090	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (114 aa)
	DsecGM17042	GM17042. (90 aa)
	DsecGM22969	GM22969. (160 aa)
	DsecGM15826	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (76 aa)
	DsecGM15924	GM15924; Belongs to the universal ribosomal protein uS9 family. (148 aa)
	DsecGM15629	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (131 aa)
	DsecGM15964	GM15964; Belongs to the universal ribosomal protein uL14 family. (140 aa)
	DsecGM15582	Ribosomal protein L37; Binds to the 23S rRNA. (89 aa)
	DsecGM15570	GM15570. (312 aa)
	DsecGM19031	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (115 aa)
	DsecGM19023	GM19023. (298 aa)
	sta	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Required during oogenesis and imaginal development. (270 aa)
	DsecGM22429	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
	DsecGM15390	GM15390. (322 aa)
	DsecGM15180	GM15180. (197 aa)
	DsecGM10227	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (135 aa)
	DsecGM10197	GM10197. (162 aa)
	DsecGM16740	GM16740; Belongs to the eukaryotic ribosomal protein P1/P2 family. (112 aa)
	DsecGM11375	GM11375. (65 aa)
	DsecGM25565	GM25565. (155 aa)
	DsecGM13451	GM13451. (134 aa)
	DsecGM13336	GM13336; Belongs to the universal ribosomal protein uS7 family. (228 aa)
	DsecGM15002	GM15002. (149 aa)
	DsecGM11558	GM11553. (144 aa)
	DsecGM11496	GM11496; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	DsecGM16347	GM16347. (164 aa)
	DsecGM16362	GM16362. (411 aa)
	DsecGM11772	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (203 aa)
	DsecGM23136	GM23136. (120 aa)
	DsecGM16427	GM16427. (243 aa)
	DsecGM12004	Ribosomal protein L37; Binds to the 23S rRNA. (94 aa)
	DsecGM17738	40S ribosomal protein S27. (84 aa)
	DsecGM22490	GM22490. (218 aa)
	DsecGM26730	GM26730. (318 aa)
	DsecGM11965	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (246 aa)
	DsecGM11985	GM11985; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	DsecGM11986	GM11986; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	RpS3A	40S ribosomal protein S3a; Essential for oogenesis; required for late follicle cell development. (268 aa)
	DsecGM23235	GM23235. (118 aa)
	DsecGM18795	GM18795. (159 aa)
	DsecGM25206	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
	DsecGM15467	GM15467. (111 aa)
	DsecGM23916	GM23916. (130 aa)
	RpS18	Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family. (152 aa)

Your Current Organism:

Drosophila sechellia

NCBI taxonomy Id: 7238
Other names: D. sechellia

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsecGM10197	DsecGM10227	B4ICJ2	B4ICC8	GM10197.	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	0.998
DsecGM10197	DsecGM10633	B4ICJ2	B4I405	GM10197.	GM10633.	0.998
DsecGM10197	DsecGM10821	B4ICJ2	B4I439	GM10197.	GM10821; Belongs to the universal ribosomal protein uL13 family.	0.998
DsecGM10197	DsecGM11214	B4ICJ2	B4HWZ5	GM10197.	GM11214.	0.986
DsecGM10197	DsecGM11375	B4ICJ2	B4IDH1	GM10197.	GM11375.	0.996
DsecGM10197	DsecGM11496	B4ICJ2	B4IGR2	GM10197.	GM11496; Belongs to the universal ribosomal protein uS8 family.	0.982
DsecGM10197	DsecGM11558	B4ICJ2	B4IGE8	GM10197.	GM11553.	0.979
DsecGM10197	DsecGM11772	B4ICJ2	B4IHB7	GM10197.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.999
DsecGM10197	DsecGM11965	B4ICJ2	B4IL48	GM10197.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.979
DsecGM10197	DsecGM11985	B4ICJ2	B4IL57	GM10197.	GM11985; Belongs to the universal ribosomal protein uS11 family.	0.962
DsecGM10197	DsecGM11986	B4ICJ2	B4IL58	GM10197.	GM11986; Belongs to the universal ribosomal protein uS11 family.	0.962
DsecGM10197	DsecGM12004	B4ICJ2	B4IJA2	GM10197.	Ribosomal protein L37; Binds to the 23S rRNA.	0.997
DsecGM10197	DsecGM12166	B4ICJ2	B4HZN9	GM10197.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.997
DsecGM10197	DsecGM12186	B4ICJ2	B4HZL1	GM10197.	GM12186.	0.999
DsecGM10197	DsecGM12191	B4ICJ2	B4HZK2	GM10197.	GM12191.	0.935
DsecGM10197	DsecGM12203	B4ICJ2	B4HWB7	GM10197.	GM12203; Belongs to the universal ribosomal protein uS5 family.	0.998
DsecGM10197	DsecGM12424	B4ICJ2	B4I0L8	GM10197.	GM12424.	0.999
DsecGM10197	DsecGM12554	B4ICJ2	B4I063	GM10197.	GM12554; Belongs to the universal ribosomal protein uL22 family.	0.999
DsecGM10197	DsecGM12569	B4ICJ2	B4I0A0	GM10197.	GM12569.	0.998
DsecGM10197	DsecGM12832	B4ICJ2	B4HZG8	GM10197.	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.	0.997