(27 nodes) Autophagy - other, and Phagophore assembly site membrane network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD21643	GD21643. (549 aa)
	DsimGD23884	GD23884. (696 aa)
	DsimGD23066	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (411 aa)
	DsimGD24068	GD24068. (242 aa)
	DsimGD11777	Phosphatidylinositol 3-kinase catalytic subunit type 3. (949 aa)
	DsimGD25379	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (684 aa)
	DsimGD10514	GD10514. (172 aa)
	Atg9	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (845 aa)
	DsimGD14059	GD14059. (435 aa)
	DsimGD13707	GD13707. (1656 aa)
	DsimGD13708	GD13708. (238 aa)
	DsimGD14768	Autophagy-related protein 3. (330 aa)
	DsimGD14360	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (111 aa)
	DsimGD12696	GD12696. (346 aa)
	DsimGD12695	GD12695; Belongs to the protein kinase superfamily. (261 aa)
	DsimGD18327	GD18327. (422 aa)
	DsimGD20217	GD20217. (227 aa)
	DsimGD19810	GD19810. (1342 aa)
	DsimGD20804	GD20804. (520 aa)
	DsimGD20813	GD20813. (1345 aa)
	DsimGD20357	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (703 aa)
	DsimGD18541	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (522 aa)
	DsimGD21414	GD21414. (503 aa)
	DsimGD17638	GD17638. (597 aa)
	DsimGD16500	GD16500. (525 aa)
	DsimGD16015	GD16015. (121 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (269 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg5	Atg9	Q3MQ14	B4QHW9	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.864
Atg5	DsimGD10514	Q3MQ14	B4QET6	Autophagy protein 5; Involved in autophagic vesicle formation.	GD10514.	0.939
Atg5	DsimGD11777	Q3MQ14	B4QAV9	Autophagy protein 5; Involved in autophagic vesicle formation.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.957
Atg5	DsimGD12695	Q3MQ14	B4QRR9	Autophagy protein 5; Involved in autophagic vesicle formation.	GD12695; Belongs to the protein kinase superfamily.	0.962
Atg5	DsimGD12696	Q3MQ14	B4QRR8	Autophagy protein 5; Involved in autophagic vesicle formation.	GD12696.	0.962
Atg5	DsimGD13707	Q3MQ14	B4QNL9	Autophagy protein 5; Involved in autophagic vesicle formation.	GD13707.	0.701
Atg5	DsimGD13708	Q3MQ14	B4QNM0	Autophagy protein 5; Involved in autophagic vesicle formation.	GD13708.	0.701
Atg5	DsimGD14059	Q3MQ14	B4QLJ4	Autophagy protein 5; Involved in autophagic vesicle formation.	GD14059.	0.967
Atg5	DsimGD14360	Q3MQ14	B4QR60	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
Atg5	DsimGD14768	Q3MQ14	B4QPW0	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 3.	0.999
Atg5	DsimGD16015	Q3MQ14	B4R7M5	Autophagy protein 5; Involved in autophagic vesicle formation.	GD16015.	0.970
Atg5	DsimGD16500	Q3MQ14	B4R7D5	Autophagy protein 5; Involved in autophagic vesicle formation.	GD16500.	0.488
Atg5	DsimGD17638	Q3MQ14	B4R0T7	Autophagy protein 5; Involved in autophagic vesicle formation.	GD17638.	0.998
Atg5	DsimGD18327	Q3MQ14	B4QSF2	Autophagy protein 5; Involved in autophagic vesicle formation.	GD18327.	0.933
Atg5	DsimGD18541	Q3MQ14	B4QYL3	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.885
Atg5	DsimGD19810	Q3MQ14	B4QX05	Autophagy protein 5; Involved in autophagic vesicle formation.	GD19810.	0.901
Atg5	DsimGD20217	Q3MQ14	B4QV49	Autophagy protein 5; Involved in autophagic vesicle formation.	GD20217.	0.969
Atg5	DsimGD20357	Q3MQ14	B4QYI4	Autophagy protein 5; Involved in autophagic vesicle formation.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.864
Atg5	DsimGD20804	Q3MQ14	B4QX75	Autophagy protein 5; Involved in autophagic vesicle formation.	GD20804.	0.816
Atg5	DsimGD20813	Q3MQ14	B4QX92	Autophagy protein 5; Involved in autophagic vesicle formation.	GD20813.	0.938