(10 nodes) Homologous DNA Pairing and Strand Exchange, and Double-stranded DNA 5-3 exodeoxyribonuclease activity network (Drosophila simulans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD12001	GD12001. (783 aa)
	DsimGD21820	GD21820. (604 aa)
	DsimGD21819	GD21819. (119 aa)
	Brca2	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity). (944 aa)
	DsimGD13015	GD13015. (659 aa)
	DsimGD21329	GD21329. (267 aa)
	DsimGD18959	Spindle B. (341 aa)
	DsimGD17366	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (336 aa)
	DsimGD17397	GD17397. (242 aa)
	DsimGD16967	GD16967. (1100 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brca2	DsimGD12001	B4QC10	B4NRT9	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD12001.	0.816
Brca2	DsimGD13015	B4QC10	B4QLI9	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD13015.	0.753
Brca2	DsimGD16967	B4QC10	B4R772	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD16967.	0.907
Brca2	DsimGD17366	B4QC10	B4R1H9	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.998
Brca2	DsimGD17397	B4QC10	B4R703	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD17397.	0.856
Brca2	DsimGD18959	B4QC10	B4QZV9	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	Spindle B.	0.983
Brca2	DsimGD21329	B4QC10	B4QXF2	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD21329.	0.983
Brca2	DsimGD21819	B4QC10	B4Q8W6	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD21819.	0.875
Brca2	DsimGD21820	B4QC10	B4Q8W5	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	GD21820.	0.875
DsimGD12001	Brca2	B4NRT9	B4QC10	GD12001.	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	0.816
DsimGD12001	DsimGD13015	B4NRT9	B4QLI9	GD12001.	GD13015.	0.775
DsimGD12001	DsimGD16967	B4NRT9	B4R772	GD12001.	GD16967.	0.784
DsimGD12001	DsimGD17366	B4NRT9	B4R1H9	GD12001.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.987
DsimGD12001	DsimGD17397	B4NRT9	B4R703	GD12001.	GD17397.	0.411
DsimGD12001	DsimGD18959	B4NRT9	B4QZV9	GD12001.	Spindle B.	0.920
DsimGD12001	DsimGD21329	B4NRT9	B4QXF2	GD12001.	GD21329.	0.917
DsimGD12001	DsimGD21819	B4NRT9	B4Q8W6	GD12001.	GD21819.	0.818
DsimGD12001	DsimGD21820	B4NRT9	B4Q8W5	GD12001.	GD21820.	0.818
DsimGD13015	Brca2	B4QLI9	B4QC10	GD13015.	Breast cancer type 2 susceptibility protein homolog; Involved in and required for double-strand break repair by meiotic and mitotic homologous recombination. During meiosis, has a dual role in the repair of meiotic double-stranded breaks and the efficient activation of the meiotic recombination checkpoint (By similarity).	0.753
DsimGD13015	DsimGD12001	B4QLI9	B4NRT9	GD13015.	GD12001.	0.775