STRINGSTRING
DsimGD17588 DsimGD17588 DsimGD24835 DsimGD24835 DsimGD24309 DsimGD24309 DsimGD23929 DsimGD23929 DsimGD23441 DsimGD23441 DsimGD21913 DsimGD21913 DsimGD24070 DsimGD24070 DsimGD24137 DsimGD24137 DsimGD24149 DsimGD24149 DsimGD22714 DsimGD22714 DsimGD24914 DsimGD24914 DsimGD10317 DsimGD10317 DsimGD25785 DsimGD25785 DsimGD10243 DsimGD10243 DsimGD25724 DsimGD25724 DsimGD25618 DsimGD25618 DsimGD10047 DsimGD10047 DsimGD14958 DsimGD14958 DsimGD13488 DsimGD13488 DsimGD12971 DsimGD12971 DsimGD14135 DsimGD14135 DsimGD13837 DsimGD13837 DsimGD18709 DsimGD18709 DsimGD18149 DsimGD18149 DsimGD20327 DsimGD20327 DsimGD18528 DsimGD18528 DsimGD18526 DsimGD18526 DsimGD20884 DsimGD20884 DsimGD18940 DsimGD18940 DsimGD18885 DsimGD18885 DsimGD16439 DsimGD16439 Mcm3 Mcm3 DsimGD16723 DsimGD16723 DsimGD16810 DsimGD16810 DsimGD16811 DsimGD16811 mei-218 mei-218 DsimGD16035 DsimGD16035
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD17588GD17588. (155 aa)
DsimGD24835GD24835; Belongs to the PI3/PI4-kinase family. (270 aa)
DsimGD24309GD24309. (775 aa)
DsimGD23929GD23929. (460 aa)
DsimGD23441GD23441. (605 aa)
DsimGD21913GD21913. (1707 aa)
DsimGD24070GD24070; Belongs to the protein kinase superfamily. (187 aa)
DsimGD24137GD24137. (664 aa)
DsimGD24149TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (157 aa)
DsimGD22714DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (203 aa)
DsimGD24914GD24914. (567 aa)
DsimGD10317GD10317. (192 aa)
DsimGD25785GD25785. (721 aa)
DsimGD10243Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (536 aa)
DsimGD25724GD25724. (893 aa)
DsimGD25618GD25618. (737 aa)
DsimGD10047GD10047. (246 aa)
DsimGD14958GD14958. (1115 aa)
DsimGD13488GD13488. (196 aa)
DsimGD12971GD12971. (225 aa)
DsimGD14135DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (607 aa)
DsimGD13837GD13837. (680 aa)
DsimGD18709DNA helicase; Belongs to the MCM family. (733 aa)
DsimGD18149DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (228 aa)
DsimGD20327GD20327; Belongs to the MCM family. (883 aa)
DsimGD18528GD18528; Belongs to the MCM family. (311 aa)
DsimGD18526GD18526. (199 aa)
DsimGD20884GD20884. (268 aa)
DsimGD18940GD18940. (618 aa)
DsimGD18885GD18885. (1333 aa)
DsimGD16439GD16439. (575 aa)
Mcm3Minichromosome maintenance 3. (264 aa)
DsimGD16723GD16723. (68 aa)
DsimGD16810GD16810. (187 aa)
DsimGD16811DNA helicase; Belongs to the MCM family. (817 aa)
mei-218Mei-218. (236 aa)
DsimGD16035GD16035. (212 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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