(13 nodes) Enoyl-CoA hydratase/isomerase, and Utilization of Ketone Bodies network (Drosophila simulans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD24579	GD24579; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa)
	DsimGD23383	GD23383. (391 aa)
	DsimGD23637	GD23637. (281 aa)
	DsimGD23638	GD23638. (280 aa)
	DsimGD23639	GD23639. (287 aa)
	DsimGD11066	GD11066. (315 aa)
	DsimGD12130	Acetyl-coenzyme A synthetase. (674 aa)
	DsimGD13579	GD13579. (262 aa)
	DsimGD13661	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (516 aa)
	DsimGD12323	GD12323. (420 aa)
	DsimGD18835	GD18835. (378 aa)
	DsimGD18069	GD18069. (318 aa)
	DsimGD21345	GD21345. (413 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD11066	DsimGD12130	B4QFW6	B4QJQ3	GD11066.	Acetyl-coenzyme A synthetase.	0.702
DsimGD11066	DsimGD12323	B4QFW6	B4QPX7	GD11066.	GD12323.	0.686
DsimGD11066	DsimGD13579	B4QFW6	B4QLG4	GD11066.	GD13579.	0.550
DsimGD11066	DsimGD13661	B4QFW6	B4QN15	GD11066.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.531
DsimGD11066	DsimGD18069	B4QFW6	B4QXI4	GD11066.	GD18069.	0.550
DsimGD11066	DsimGD18835	B4QFW6	B4QSA7	GD11066.	GD18835.	0.550
DsimGD11066	DsimGD21345	B4QFW6	B4QY28	GD11066.	GD21345.	0.926
DsimGD11066	DsimGD23383	B4QFW6	B4Q4I2	GD11066.	GD23383.	0.897
DsimGD11066	DsimGD23637	B4QFW6	B4Q896	GD11066.	GD23637.	0.550
DsimGD11066	DsimGD23638	B4QFW6	B4Q897	GD11066.	GD23638.	0.550
DsimGD11066	DsimGD23639	B4QFW6	B4Q898	GD11066.	GD23639.	0.550
DsimGD11066	DsimGD24579	B4QFW6	B4NU45	GD11066.	GD24579; Belongs to the thiolase-like superfamily. Thiolase family.	0.897
DsimGD12130	DsimGD11066	B4QJQ3	B4QFW6	Acetyl-coenzyme A synthetase.	GD11066.	0.702
DsimGD12130	DsimGD12323	B4QJQ3	B4QPX7	Acetyl-coenzyme A synthetase.	GD12323.	0.572
DsimGD12130	DsimGD13579	B4QJQ3	B4QLG4	Acetyl-coenzyme A synthetase.	GD13579.	0.583
DsimGD12130	DsimGD13661	B4QJQ3	B4QN15	Acetyl-coenzyme A synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.440
DsimGD12130	DsimGD18069	B4QJQ3	B4QXI4	Acetyl-coenzyme A synthetase.	GD18069.	0.617
DsimGD12130	DsimGD18835	B4QJQ3	B4QSA7	Acetyl-coenzyme A synthetase.	GD18835.	0.617
DsimGD12130	DsimGD21345	B4QJQ3	B4QY28	Acetyl-coenzyme A synthetase.	GD21345.	0.918
DsimGD12130	DsimGD23383	B4QJQ3	B4Q4I2	Acetyl-coenzyme A synthetase.	GD23383.	0.723