STRINGSTRING
DsimGD12000 DsimGD12000 DsimGD22671 DsimGD22671 DsimGD21646 DsimGD21646 DsimGD23515 DsimGD23515 DsimGD23516 DsimGD23516 DsimGD23517 DsimGD23517 DsimGD22791 DsimGD22791 DsimGD23751 DsimGD23751 DsimGD10747 DsimGD10747 DsimGD11264 DsimGD11264 DsimGD11273 DsimGD11273 DsimGD11274 DsimGD11274 DsimGD11275 DsimGD11275 DsimGD11843 DsimGD11843 DsimGD25418 DsimGD25418 DsimGD25095 DsimGD25095 DsimGD12680 DsimGD12680 DsimGD13427 DsimGD13427 DsimGD12382 DsimGD12382 DsimGD14773 DsimGD14773 DsimGD14864 DsimGD14864 DsimGD18802 DsimGD18802 DsimGD21086 DsimGD21086 DsimGD18755 DsimGD18755 DsimGD18150 DsimGD18150 DsimGD18110 DsimGD18110 DsimGD18595 DsimGD18595 DsimGD20479 DsimGD20479 DsimGD17001 DsimGD17001 DsimGD15638 DsimGD15638 DsimGD16985 DsimGD16985
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD12000GD12000. (279 aa)
DsimGD22671Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa)
DsimGD21646GD21646. (677 aa)
DsimGD23515Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (158 aa)
DsimGD23516Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (170 aa)
DsimGD23517GD23517. (264 aa)
DsimGD22791GD22791; Belongs to the GDA1/CD39 NTPase family. (464 aa)
DsimGD23751GD23751. (188 aa)
DsimGD10747GD10747. (790 aa)
DsimGD11264Uridine kinase; Belongs to the uridine kinase family. (625 aa)
DsimGD11273GD11273; Belongs to the 5'-nucleotidase family. (599 aa)
DsimGD11274GD11274; Belongs to the 5'-nucleotidase family. (585 aa)
DsimGD11275GD11275; Belongs to the 5'-nucleotidase family. (579 aa)
DsimGD118435'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (319 aa)
DsimGD25418GD25418. (211 aa)
DsimGD25095Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (378 aa)
DsimGD12680GD12680. (345 aa)
DsimGD13427GD13427. (182 aa)
DsimGD12382GD12382. (520 aa)
DsimGD14773GD14773. (333 aa)
DsimGD14864GD14864. (187 aa)
DsimGD18802GD18802. (347 aa)
DsimGD21086GD21086. (260 aa)
DsimGD18755GD18755. (420 aa)
DsimGD18150UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (253 aa)
DsimGD18110GD18110. (347 aa)
DsimGD18595GD18595. (337 aa)
DsimGD20479GD20479. (502 aa)
DsimGD17001GD17001. (190 aa)
DsimGD15638GD15638. (403 aa)
DsimGD16985Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (527 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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