78 items (Drosophila simulans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD15533	GD15533. (1804 aa)
	DsimGD15323	GD15323. (134 aa)
	DsimGD17722	GD17722. (152 aa)
	Dsimosa	Osa. (752 aa)
	DsimGD15478	GD15478. (226 aa)
	DsimGD24822	GD24822. (112 aa)
	DsimGD24470	GD24470; Belongs to the cytochrome P450 family. (538 aa)
	DsimGD24871	GD24871. (203 aa)
	DsimGD24441	GD24441. (116 aa)
	DsimGD24377	GD24377. (243 aa)
	DsimGD24448	GD24448. (113 aa)
	DsimGD14331	GD14331. (313 aa)
	DsimGD23059	GD23059. (185 aa)
	Sos	Sos. (1595 aa)
	Su(H)	Su(H). (594 aa)
	DsimGD23020	GD23020. (410 aa)
	DsimGD22944	GD22944. (3038 aa)
	DsimGD23128	E3 ubiquitin-protein ligase. (949 aa)
	DsimGD22774	Mothers against decapentaplegic homolog. (440 aa)
	DsimGD23242	GD23242. (81 aa)
	DsimGD22744	GD22744. (576 aa)
	DsimGD22743	GD22743. (391 aa)
	DsimGD23254	GD23254. (1439 aa)
	DsimGD25460	GD25460. (798 aa)
	DsimGD25459	GD25459. (195 aa)
	DsimGD24977	GD24977; Belongs to the actin-binding proteins ADF family. (148 aa)
	DsimGD11901	GD11901. (327 aa)
	DsimGD10352	GD10352. (469 aa)
	DsimGD25385	GD25385. (932 aa)
	DsimGD10928	GD10928. (453 aa)
	DsimGD25595	GD25595. (425 aa)
	DsimGD11656	GD11656. (130 aa)
	DsimGD11158	GD11158. (192 aa)
	DsimGD12147	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2731 aa)
	DsimGD14977	GD14977. (461 aa)
	DsimGD14028	GD14028. (1311 aa)
	DsimGD14559	GD14559. (567 aa)
	DsimGD13500	GD13500. (706 aa)
	DsimGD14095	GD14095. (829 aa)
	DsimGD14132	GD14132. (127 aa)
	DsimGD14134	GD14134; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (560 aa)
	DsimGD14683	GD14683. (1028 aa)
	DsimGD12888	GD12888; Belongs to the protein kinase superfamily. (451 aa)
	DsimGD12327	GD12327. (1024 aa)
	DsimGD14791	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (481 aa)
	DsimGD13862	GD13862. (1979 aa)
	DsimGD14361	GD14361. (287 aa)
	DsimGD14362	GD14362. (57 aa)
	DsimGD14832	GD14832. (640 aa)
	DsimGD12217	GD12217. (593 aa)
	DsimGD13891	GD13891. (1889 aa)
	DsimGD21590	GD21590. (196 aa)
	DsimGD19322	GD19322. (731 aa)
	Dl	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (823 aa)
	DsimGD20218	GD20218. (640 aa)
	DsimGD20718	GD20718. (487 aa)
	DsimGD18145	GD18145. (644 aa)
	DsimUbx	Ultrabithorax. (338 aa)
	DsimGD20292	GD20292. (1075 aa)
	DsimGD18591	GD18591. (538 aa)
	DsimGD20825	GD20825. (424 aa)
	DsimGD18089	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1388 aa)
	DsimGD19869	Non-specific serine/threonine protein kinase. (701 aa)
	DsimGD20395	GD20395; Belongs to the cyclin family. (267 aa)
	DsimGD19488	GD19488. (943 aa)
	DsimGD19430	GD19430. (339 aa)
	DsimGD19976	GD19976. (479 aa)
	DsimGD19977	GD19977. (412 aa)
	N	Notch. (811 aa)
	DsimGD16254	GD16254. (495 aa)
	DsimGD17324	GD17324. (314 aa)
	DsimGD17354	GD17354. (1731 aa)
	Lim1	Lim1. (345 aa)
	DsimGD17385	GD17385. (760 aa)
	DsimGD17400	GD17400. (371 aa)
	DsimGD16963	GD16963. (204 aa)
	DsimGD16964	GD16964. (793 aa)
	DsimGD17439	GD17439. (88 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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Export your current network:

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file format is 'PNG': portable network graphic

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dl	DsimGD18089	B4QTE8	B4QXF3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.694
Dl	N	B4QTE8	B4R3W6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch.	0.999
Dl	Su(H)	B4QTE8	B4Q5Z2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Su(H).	0.532
DsimGD10352	DsimGD10928	B4QCN8	B4QDI6	GD10352.	GD10928.	0.454
DsimGD10352	DsimGD17400	B4QCN8	B4R708	GD10352.	GD17400.	0.918
DsimGD10928	DsimGD10352	B4QDI6	B4QCN8	GD10928.	GD10352.	0.454
DsimGD10928	DsimGD24822	B4QDI6	B4NUH5	GD10928.	GD24822.	0.995
DsimGD11158	DsimGD12217	B4QHF0	B4QRG9	GD11158.	GD12217.	0.791
DsimGD11158	DsimGD13500	B4QHF0	B4QLH7	GD11158.	GD13500.	0.915
DsimGD11158	DsimGD13862	B4QHF0	B4QR24	GD11158.	GD13862.	0.715
DsimGD11158	DsimGD14361	B4QHF0	B4QR62	GD11158.	GD14361.	0.805
DsimGD11158	DsimGD14362	B4QHF0	B4QR63	GD11158.	GD14362.	0.805
DsimGD11158	DsimGD14559	B4QHF0	B4QL43	GD11158.	GD14559.	0.779
DsimGD11158	DsimGD14683	B4QHF0	B4QND4	GD11158.	GD14683.	0.699
DsimGD11158	DsimGD15478	B4QHF0	B4NTL8	GD11158.	GD15478.	0.475
DsimGD11158	DsimGD15533	B4QHF0	B4R2Z0	GD11158.	GD15533.	0.475
DsimGD11158	DsimGD16254	B4QHF0	B4R4Z8	GD11158.	GD16254.	0.662
DsimGD11158	DsimGD17324	B4QHF0	B4R658	GD11158.	GD17324.	0.600
DsimGD11158	DsimGD17354	B4QHF0	B4R6M8	GD11158.	GD17354.	0.521
DsimGD11158	DsimGD17385	B4QHF0	B4R6X2	GD11158.	GD17385.	0.451