(41 nodes) Neuroblast fate commitment network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD23007	GD23007. (1088 aa)
	DsimGD23911	GD23911. (915 aa)
	DsimGD23341	GD23341. (581 aa)
	DsimGD15080	GD15080. (183 aa)
	DsimGD24561	GD24561. (285 aa)
	Dsimosa	Osa. (752 aa)
	DsimGD15118	GD15118. (266 aa)
	DsimGD17722	GD17722. (152 aa)
	DsimGD15323	GD15323. (134 aa)
	DsimGD16514	GD16514. (723 aa)
	DsimGD16504	GD16504. (466 aa)
	sc	Scute. (334 aa)
	DsimGD15481	GD15481. (428 aa)
	N	Notch. (811 aa)
	run	Runt. (510 aa)
	DsimGD16405	GD16405. (169 aa)
	DsimGD21441	GD21441. (514 aa)
	DsimGD20824	GD20824. (671 aa)
	DsimGD20268	GD20268. (631 aa)
	DsimGD20218	GD20218. (640 aa)
	DsimGD19684	GD19684. (297 aa)
	pros	Prospero. (623 aa)
	Dl	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (823 aa)
	DsimGD12309	GD12309. (926 aa)
	DsimGD12586	GD12586. (319 aa)
	DsimGD25250	GD25250. (204 aa)
	DsimGD11001	GD11001. (565 aa)
	DsimGD11000	GD11000. (702 aa)
	DsimGD10998	GD10998. (275 aa)
	DsimGD11921	GD11921. (498 aa)
	DsimGD25416	GD25416. (1035 aa)
	en	Homeobox protein engrailed-like. (555 aa)
	DsimGD10802	Homeobox protein engrailed-like. (452 aa)
	DsimGD24189	GD24189. (378 aa)
	DsimGD24188	GD24188. (547 aa)
	DsimGD23692	GD23692. (354 aa)
	DsimGD23691	GD23691. (314 aa)
	DsimGD21809	GD21809. (1112 aa)
	DsimGD21944	GD21944; Belongs to the cyclin family. (701 aa)
	DsimGD23006	GD23006. (1098 aa)
	l(1)sc	Lethal of scute. (257 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dl	DsimGD15481	B4QTE8	B4R447	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GD15481.	0.425
Dl	DsimGD20824	B4QTE8	B4QXA9	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GD20824.	0.988
Dl	DsimGD21441	B4QTE8	B4R049	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GD21441.	0.583
Dl	DsimGD23911	B4QTE8	B4Q539	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GD23911.	0.425
Dl	N	B4QTE8	B4R3W6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch.	0.999
DsimGD10802	en	B4QBL9	B4QBM1	Homeobox protein engrailed-like.	Homeobox protein engrailed-like.	0.470
DsimGD10998	DsimGD11000	B4QEX2	B4QEX4	GD10998.	GD11000.	0.576
DsimGD10998	DsimGD11001	B4QEX2	B4QEX5	GD10998.	GD11001.	0.579
DsimGD10998	N	B4QEX2	B4R3W6	GD10998.	Notch.	0.643
DsimGD11000	DsimGD10998	B4QEX4	B4QEX2	GD11000.	GD10998.	0.576
DsimGD11000	DsimGD11001	B4QEX4	B4QEX5	GD11000.	GD11001.	0.591
DsimGD11000	N	B4QEX4	B4R3W6	GD11000.	Notch.	0.990
DsimGD11001	DsimGD10998	B4QEX5	B4QEX2	GD11001.	GD10998.	0.579
DsimGD11001	DsimGD11000	B4QEX5	B4QEX4	GD11001.	GD11000.	0.591
DsimGD11001	N	B4QEX5	B4R3W6	GD11001.	Notch.	0.906
DsimGD12586	DsimGD19684	B4QKI7	B4QV07	GD12586.	GD19684.	0.588
DsimGD15080	en	B4NVW7	B4QBM1	GD15080.	Homeobox protein engrailed-like.	0.408
DsimGD15118	DsimGD19684	B4NT90	B4QV07	GD15118.	GD19684.	0.871
DsimGD15118	DsimGD20268	B4NT90	B4QWF0	GD15118.	GD20268.	0.443
DsimGD15323	DsimGD21809	B4NS20	B4Q8Y3	GD15323.	GD21809.	0.535