(92 nodes) Cell growth network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD17184	GD17184. (295 aa)
	DsimGD11978	GD11978. (317 aa)
	DsimGD15116	GD15116. (139 aa)
	DsimGD15185	GD15185. (263 aa)
	DsimGD24573	GD24573. (525 aa)
	DsimGD24548	GD24548. (234 aa)
	DsimGD24547	GD24547. (507 aa)
	DsimGD24485	GD24485. (68 aa)
	DsimGD22659	GD22659. (129 aa)
	DsimGD23428	GD23428. (1201 aa)
	DsimGD22444	GD22444. (1329 aa)
	DsimGD22345	GD22345; Belongs to the protein kinase superfamily. (353 aa)
	DsimGD22841	GD22841. (219 aa)
	DsimGD21853	GD21853; Cadherins are calcium-dependent cell adhesion proteins. (1402 aa)
	DsimGD21851	GD21851; Cadherins are calcium-dependent cell adhesion proteins. (2044 aa)
	DsimGD22290	GD22290. (224 aa)
	DsimGD22289	Mitogen-activated protein kinase. (372 aa)
	DsimGD23745	GD23745. (260 aa)
	DsimGD23746	GD23746. (332 aa)
	DsimGD24230	GD24230. (2043 aa)
	DsimGD23276	GD23276. (240 aa)
	DsimGD22703	GD22703. (262 aa)
	DsimGD22702	GD22702. (373 aa)
	DsimGD23750	GD23750. (844 aa)
	DsimGD10353	GD10353. (327 aa)
	DsimGD10351	GD10351. (103 aa)
	DsimGD10344	GD10344. (1298 aa)
	DsimGD10928	GD10928. (453 aa)
	DsimGD10266	GD10266. (2908 aa)
	DsimGD25759	GD25759. (1274 aa)
	DsimGD25758	GD25758. (403 aa)
	DsimGD11013	GD11013. (270 aa)
	DsimGD25233	GD25233. (410 aa)
	DsimGD25232	GD25232. (536 aa)
	DsimGD11105	GD11105; Belongs to the integrin alpha chain family. (1115 aa)
	DsimGD11106	GD11106; Belongs to the integrin alpha chain family. (1068 aa)
	DsimGD25618	GD25618. (737 aa)
	DsimGD10659	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (324 aa)
	DsimGD11158	GD11158. (192 aa)
	DsimGD25560	Tyrosine-protein kinase. (934 aa)
	DsimGD25104	GD25104. (1815 aa)
	DsimGD11240	GD11240. (2562 aa)
	DsimGD11776	GD11776; Belongs to the integrin alpha chain family. (1003 aa)
	DsimGD14461	GD14461. (317 aa)
	DsimGD14462	GD14462. (941 aa)
	DsimGD14478	GD14478. (1277 aa)
	DsimGD14489	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family. (415 aa)
	DsimGD13056	GD13056. (192 aa)
	DsimGD13560	GD13560. (53 aa)
	DsimGD13040	GD13040. (549 aa)
	DsimGD13039	GD13039. (1346 aa)
	DsimGD13038	GD13038. (1515 aa)
	DsimGD13561	GD13561. (315 aa)
	DsimGD14082	GD14082. (285 aa)
	DsimGD13487	GD13487. (192 aa)
	DsimGD13625	GD13625. (299 aa)
	DsimGD12915	GD12915. (519 aa)
	DsimGD13333	GD13333. (361 aa)
	DsimGD13332	GD13332. (286 aa)
	DsimGD12297	GD12297; Belongs to the G-protein coupled receptor Fz/Smo family. (693 aa)
	DsimGD13260	GD13260. (146 aa)
	DsimGD12264	Mitogen-activated protein kinase kinase kinase. (980 aa)
	DsimGD12696	GD12696. (346 aa)
	DsimGD12695	GD12695; Belongs to the protein kinase superfamily. (261 aa)
	DsimGD21608	GD21608. (1826 aa)
	DsimGD20204	Fibroblast growth factor receptor. (727 aa)
	DsimGD20767	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	DsimGD21256	GD21256. (1287 aa)
	DsimGD19135	Mothers against decapentaplegic homolog. (570 aa)
	DsimGD20803	Tyrosine-protein kinase. (1214 aa)
	DsimGD21343	GD21343. (184 aa)
	DsimGD19818	GD19818. (197 aa)
	DsimGD19971	GD19971. (1814 aa)
	DsimGD19972	GD19972. (270 aa)
	DsimGD20455	GD20455. (473 aa)
	DsimGD19397	GD19397. (198 aa)
	pan	Pan. (500 aa)
	DsimGD16405	GD16405. (169 aa)
	DsimGD16636	GD16636. (527 aa)
	DsimGD16638	Phosphodiesterase. (862 aa)
	DsimGD16639	GD16639. (125 aa)
	DsimGD15909	GD15909. (1047 aa)
	rut	Rutabaga; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (2207 aa)
	DsimGD17183	GD17183. (202 aa)
	sqh	Sqh. (174 aa)
	DsimGD16840	GD16840. (624 aa)
	DsimGD16907	GD16907. (601 aa)
	DsimGD15656	GD15656. (190 aa)
	DsimGD15655	GD15655; Belongs to the potassium channel family. (518 aa)
	DsimGD15629	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (969 aa)
	DsimGD16029	GD16029. (390 aa)
	DsimGD17456	GD17456. (191 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD10266	DsimGD21853	B4QE83	B4Q8C6	GD10266.	GD21853; Cadherins are calcium-dependent cell adhesion proteins.	0.598
DsimGD10351	DsimGD15185	B4QCN9	B4NTG2	GD10351.	GD15185.	0.524
DsimGD10351	DsimGD19397	B4QCN9	B4R145	GD10351.	GD19397.	0.406
DsimGD10351	DsimGD21256	B4QCN9	B4QW05	GD10351.	GD21256.	0.467
DsimGD10659	DsimGD12297	B4QH98	B4QQD4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	GD12297; Belongs to the G-protein coupled receptor Fz/Smo family.	0.829
DsimGD10659	DsimGD14489	B4QH98	B4QJZ3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	0.927
DsimGD10659	DsimGD15629	B4QH98	B4R704	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.610
DsimGD10659	DsimGD16405	B4QH98	B4R322	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	GD16405.	0.514
DsimGD10659	DsimGD25758	B4QH98	B4QEE1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	GD25758.	0.834
DsimGD10659	DsimGD25759	B4QH98	B4QEE0	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	GD25759.	0.834
DsimGD11105	DsimGD11106	B4QGF1	B4QGF2	GD11105; Belongs to the integrin alpha chain family.	GD11106; Belongs to the integrin alpha chain family.	0.446
DsimGD11105	DsimGD11776	B4QGF1	B4QIR7	GD11105; Belongs to the integrin alpha chain family.	GD11776; Belongs to the integrin alpha chain family.	0.445
DsimGD11106	DsimGD11105	B4QGF2	B4QGF1	GD11106; Belongs to the integrin alpha chain family.	GD11105; Belongs to the integrin alpha chain family.	0.446
DsimGD11106	DsimGD11776	B4QGF2	B4QIR7	GD11106; Belongs to the integrin alpha chain family.	GD11776; Belongs to the integrin alpha chain family.	0.453
DsimGD11158	DsimGD11240	B4QHF0	B4QIJ3	GD11158.	GD11240.	0.987
DsimGD11158	DsimGD13056	B4QHF0	B4QKE8	GD11158.	GD13056.	0.722
DsimGD11158	DsimGD13487	B4QHF0	B4QLZ5	GD11158.	GD13487.	0.962
DsimGD11158	DsimGD14478	B4QHF0	B4QJK4	GD11158.	GD14478.	0.743
DsimGD11158	DsimGD14489	B4QHF0	B4QJZ3	GD11158.	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	0.605
DsimGD11158	DsimGD16405	B4QHF0	B4R322	GD11158.	GD16405.	0.732