(34 nodes) Axon midline choice point recognition network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	plexA	PlexA. (900 aa)
	DsimGD19699	GD19699. (120 aa)
	Sos	Sos. (1595 aa)
	DsimGD23556	GD23556; Belongs to the semaphorin family. (897 aa)
	DsimGD23716	GD23716. (342 aa)
	DsimGD23717	GD23717. (600 aa)
	DsimGD24191	GD24191. (610 aa)
	DsimGD23274	GD23274. (434 aa)
	DsimGD23275	GD23275. (443 aa)
	DsimGD25977	GD25977. (445 aa)
	DsimGD25971	GD25971. (335 aa)
	DsimGD25968	GD25968. (261 aa)
	DsimGD25966	GD25966. (369 aa)
	lola	GD25965. (671 aa)
	DsimGD10904	GD10904. (432 aa)
	DsimGD15677	GD15677. (1205 aa)
	DsimGD25734	GD25734. (690 aa)
	DsimGD25733	GD25733. (4046 aa)
	DsimGD25590	GD25590. (1506 aa)
	DsimGD25109	GD25109. (1429 aa)
	DsimGD12538	GD12538. (370 aa)
	DsimGD13597	GD13597. (621 aa)
	DsimGD13487	GD13487. (192 aa)
	DsimGD13438	GD13438. (2447 aa)
	DsimGD12452	GD12452. (1421 aa)
	DsimGD14715	GD14715. (249 aa)
	DsimGD14716	GD14716. (700 aa)
	DsimGD12253	Guanylate cyclase. (1522 aa)
	DsimGD12709	GD12709. (312 aa)
	fru	Fru. (1021 aa)
	DsimGD19602	GD19602. (162 aa)
	DsimGD19448	GD19448. (178 aa)
	DsimGD19445	GD19445. (387 aa)
	DsimGD20009	GD20009. (1168 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD12253	DsimGD23556	B4QQX8	B4Q780	Guanylate cyclase.	GD23556; Belongs to the semaphorin family.	0.626
DsimGD12253	plexA	B4QQX8	B4R2H9	Guanylate cyclase.	PlexA.	0.632
DsimGD12452	DsimGD13487	B4QMW5	B4QLZ5	GD12452.	GD13487.	0.529
DsimGD12452	DsimGD14715	B4QMW5	B4QNW5	GD12452.	GD14715.	0.401
DsimGD12452	DsimGD14716	B4QMW5	B4QNW6	GD12452.	GD14716.	0.401
DsimGD12452	DsimGD19699	B4QMW5	B4NVG3	GD12452.	GD19699.	0.401
DsimGD12452	DsimGD25109	B4QMW5	B4QHL6	GD12452.	GD25109.	0.922
DsimGD12452	DsimGD25590	B4QMW5	B4QGZ8	GD12452.	GD25590.	0.841
DsimGD12538	DsimGD14715	B4QL68	B4QNW5	GD12538.	GD14715.	0.818
DsimGD12538	DsimGD14716	B4QL68	B4QNW6	GD12538.	GD14716.	0.818
DsimGD12538	DsimGD19699	B4QL68	B4NVG3	GD12538.	GD19699.	0.818
DsimGD12538	DsimGD25109	B4QL68	B4QHL6	GD12538.	GD25109.	0.916
DsimGD13438	DsimGD13487	B4QMK8	B4QLZ5	GD13438.	GD13487.	0.410
DsimGD13438	DsimGD15677	B4QMK8	B4R6L6	GD13438.	GD15677.	0.996
DsimGD13438	DsimGD25733	B4QMK8	B4QEV5	GD13438.	GD25733.	0.570
DsimGD13438	DsimGD25734	B4QMK8	B4QEV4	GD13438.	GD25734.	0.570
DsimGD13438	Sos	B4QMK8	B4Q565	GD13438.	Sos.	0.476
DsimGD13487	DsimGD12452	B4QLZ5	B4QMW5	GD13487.	GD12452.	0.529
DsimGD13487	DsimGD13438	B4QLZ5	B4QMK8	GD13487.	GD13438.	0.410
DsimGD13487	DsimGD23556	B4QLZ5	B4Q780	GD13487.	GD23556; Belongs to the semaphorin family.	0.409