STRINGSTRING
DsimGD12010 DsimGD12010 DsimGD16140 DsimGD16140 DsimGD17202 DsimGD17202 DsimGD16701 DsimGD16701 DsimGD15970 DsimGD15970 DsimGD16553 DsimGD16553 DsimGD24374 DsimGD24374 DsimGD21513 DsimGD21513 DsimGD18428 DsimGD18428 Dcr-1 Dcr-1 Hsc70-4 Hsc70-4 DsimGD20854 DsimGD20854 DsimGD19053 DsimGD19053 DsimGD19568 DsimGD19568 DsimGD20820 DsimGD20820 DsimGD20819 DsimGD20819 DsimGD20817 DsimGD20817 Cbp20 Cbp20 DsimGD21592 DsimGD21592 DsimGD13198 DsimGD13198 DsimGD13767 DsimGD13767 DsimGD13431 DsimGD13431 DsimGD12535 DsimGD12535 AGO2 AGO2 DsimGD14504 DsimGD14504 DsimGD13105 DsimGD13105 DsimGD11245 DsimGD11245 DsimGD25725 DsimGD25725 AGO1 AGO1 Ars2 Ars2 DsimGD24975 DsimGD24975 Dcr-2 Dcr-2 DsimGD25978 DsimGD25978 DsimGD22196 DsimGD22196 DsimGD22205 DsimGD22205 DsimGD22206 DsimGD22206 DsimGD23667 DsimGD23667 DsimGD23623 DsimGD23623 DsimGD21970 DsimGD21970 DsimGD22526 DsimGD22526 DsimGD24356 DsimGD24356 DsimGD24355 DsimGD24355 DsimGD14121 DsimGD14121 DsimGD24743 DsimGD24743 DsimGD15194 DsimGD15194 DsimGD15121 DsimGD15121 DsimGD12042 DsimGD12042
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD12010GD12010. (603 aa)
DsimGD16140GD16140; Belongs to the DEAD box helicase family. (800 aa)
DsimGD17202GD17202. (983 aa)
DsimGD16701GD16701. (409 aa)
DsimGD15970GD15970. (456 aa)
DsimGD16553GD16553. (226 aa)
DsimGD24374GD24374. (1164 aa)
DsimGD21513GD21513. (911 aa)
DsimGD18428GD18428. (690 aa)
Dcr-1Dicer-1. (1533 aa)
Hsc70-4Hsc70-4; Belongs to the heat shock protein 70 family. (651 aa)
DsimGD20854GD20854; Belongs to the DEAD box helicase family. (784 aa)
DsimGD19053GD19053. (840 aa)
DsimGD19568GD19568. (290 aa)
DsimGD20820GD20820. (701 aa)
DsimGD20819GD20819. (66 aa)
DsimGD20817GD20817. (327 aa)
Cbp20Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs [...] (154 aa)
DsimGD21592GD21592. (642 aa)
DsimGD13198GD13198. (257 aa)
DsimGD13767GD13767. (859 aa)
DsimGD13431GD13431. (670 aa)
DsimGD12535GD12535. (768 aa)
AGO2AGO2. (759 aa)
DsimGD14504GD14504. (1577 aa)
DsimGD13105GD13105. (814 aa)
DsimGD11245GD11245. (787 aa)
DsimGD25725GD25725. (1316 aa)
AGO1Argonaute 1. (447 aa)
Ars2Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi). Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity). (947 aa)
DsimGD24975GD24975; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (299 aa)
Dcr-2Dcr-2; Belongs to the helicase family. Dicer subfamily. (1666 aa)
DsimGD25978GD25978. (230 aa)
DsimGD22196GD22196. (1353 aa)
DsimGD22205GD22205; Belongs to the argonaute family. (857 aa)
DsimGD22206GD22206; Belongs to the argonaute family. (843 aa)
DsimGD23667GD23667; Belongs to the DEAD box helicase family. (459 aa)
DsimGD23623Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (394 aa)
DsimGD21970GD21970. (520 aa)
DsimGD22526GD22526. (227 aa)
DsimGD24356GD24356. (1087 aa)
DsimGD24355GD24355. (259 aa)
DsimGD14121GD14121. (202 aa)
DsimGD24743GD24743. (306 aa)
DsimGD15194GD15194. (119 aa)
DsimGD15121GD15121. (163 aa)
DsimGD12042GD12042. (280 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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