(13 nodes) TBP-class protein binding network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD19062	GD19062. (496 aa)
	DsimGD15189	GD15189. (81 aa)
	DsimGD24638	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (107 aa)
	DsimGD23986	GD23986. (183 aa)
	DsimGD23702	GD23702. (315 aa)
	DsimGD12884	GD12884. (1224 aa)
	DsimGD20646	GD20646. (194 aa)
	DsimGD20238	GD20238. (662 aa)
	DsimGD21332	GD21332. (115 aa)
	DsimGD19063	GD19063. (1403 aa)
	DsimGD19886	GD19886. (2131 aa)
	DsimGD18345	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	DsimGD17278	GD17278. (393 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD12884	DsimGD15189	B4QNQ8	B4NTG8	GD12884.	GD15189.	0.766
DsimGD12884	DsimGD18345	B4QNQ8	B4R261	GD12884.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.808
DsimGD12884	DsimGD19062	B4QNQ8	B4QXS0	GD12884.	GD19062.	0.548
DsimGD12884	DsimGD19063	B4QNQ8	B4QXR9	GD12884.	GD19063.	0.548
DsimGD12884	DsimGD19886	B4QNQ8	B4QYD5	GD12884.	GD19886.	0.999
DsimGD12884	DsimGD20646	B4QNQ8	B4QTN1	GD12884.	GD20646.	0.999
DsimGD12884	DsimGD21332	B4QNQ8	B4QXF8	GD12884.	GD21332.	0.766
DsimGD12884	DsimGD23702	B4QNQ8	B4Q9A4	GD12884.	GD23702.	0.969
DsimGD12884	DsimGD24638	B4QNQ8	B4NTT5	GD12884.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.808
DsimGD15189	DsimGD12884	B4NTG8	B4QNQ8	GD15189.	GD12884.	0.766
DsimGD15189	DsimGD18345	B4NTG8	B4R261	GD15189.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.994
DsimGD15189	DsimGD19886	B4NTG8	B4QYD5	GD15189.	GD19886.	0.805
DsimGD15189	DsimGD20646	B4NTG8	B4QTN1	GD15189.	GD20646.	0.824
DsimGD15189	DsimGD21332	B4NTG8	B4QXF8	GD15189.	GD21332.	0.666
DsimGD15189	DsimGD23702	B4NTG8	B4Q9A4	GD15189.	GD23702.	0.955
DsimGD15189	DsimGD24638	B4NTG8	B4NTT5	GD15189.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.928
DsimGD18345	DsimGD12884	B4R261	B4QNQ8	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	GD12884.	0.808
DsimGD18345	DsimGD15189	B4R261	B4NTG8	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	GD15189.	0.994
DsimGD18345	DsimGD19886	B4R261	B4QYD5	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	GD19886.	0.871
DsimGD18345	DsimGD20646	B4R261	B4QTN1	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	GD20646.	0.831