91 items (Drosophila simulans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD23030	GD23030. (675 aa)
	DsimGD17439	GD17439. (88 aa)
	DsimGD16504	GD16504. (466 aa)
	sc	Scute. (334 aa)
	DsimGD17400	GD17400. (371 aa)
	DsimGD15666	GD15666. (638 aa)
	DsimGD15668	GD15668. (547 aa)
	DsimGD17341	GD17341. (829 aa)
	DsimGD15701	GD15701. (428 aa)
	DsimGD15700	GD15700. (407 aa)
	DsimGD15772	GD15772. (111 aa)
	N	Notch. (811 aa)
	DsimGD16630	GD16630. (705 aa)
	DsimGD16346	GD16346. (805 aa)
	DsimGD15978	GD15978. (549 aa)
	DsimGD18873	GD18873; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (386 aa)
	DsimGD18402	GD18402. (581 aa)
	DsimGD20007	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (766 aa)
	DsimGD19397	GD19397. (198 aa)
	DsimGD20455	GD20455. (473 aa)
	DsimGD18947	GD18947. (341 aa)
	DsimGD19430	GD19430. (339 aa)
	DsimGD19488	GD19488. (943 aa)
	DsimGD20395	GD20395; Belongs to the cyclin family. (267 aa)
	DsimGD18015	GD18015. (527 aa)
	DsimGD19013	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1243 aa)
	DsimGD19023	GD19023. (581 aa)
	DsimGD20836	GD20836. (1693 aa)
	DsimGD19818	GD19818. (197 aa)
	DsimGD18591	GD18591. (538 aa)
	DsimGD19092	GD19092. (910 aa)
	msi	Msi. (459 aa)
	DsimGD20695	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (251 aa)
	DsimGD20133	GD20133. (313 aa)
	Dl	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (823 aa)
	mira	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (462 aa)
	DsimGD21567	GD21567. (364 aa)
	DsimGD14832	GD14832. (640 aa)
	DsimGD12245	GD12245; Belongs to the protein kinase superfamily. (459 aa)
	DsimGD14228	GD14228; Belongs to the peptidase C14A family. (449 aa)
	DsimGD12888	GD12888; Belongs to the protein kinase superfamily. (451 aa)
	DsimGD12424	GD12424. (119 aa)
	DsimGD12903	GD12903. (1459 aa)
	DsimGD12904	GD12904. (375 aa)
	DsimGD12905	GD12905. (1460 aa)
	DsimGD13672	GD13672; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1049 aa)
	DsimGD14134	GD14134; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (560 aa)
	DsimGD14132	GD14132. (127 aa)
	DsimGD12518	GD12518. (430 aa)
	DsimGD13571	GD13571. (199 aa)
	DsimGD13022	GD13022. (92 aa)
	DsimGD12069	GD12069. (238 aa)
	Hem	Hem. (1126 aa)
	DsimGD12147	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2731 aa)
	DsimGD12654	GD12654. (531 aa)
	DsimGD13123	GD13123. (1792 aa)
	DsimGD12667	GD12667. (540 aa)
	DsimGD11771	GD11771. (925 aa)
	DsimGD11239	GD11239. (1421 aa)
	DsimGD25587	GD25587. (498 aa)
	DsimGD11630	GD11630. (176 aa)
	DsimGD10605	GD10605. (1014 aa)
	DsimGD10603	GD10603. (328 aa)
	DsimGD25197	Peptidylprolyl isomerase. (231 aa)
	DsimGD10469	GD10469. (359 aa)
	DsimGD10930	GD10930. (1531 aa)
	DsimGD10921	GD10921. (498 aa)
	DsimGD10920	GD10920. (278 aa)
	DsimGD11849	GD11849. (878 aa)
	DsimGD24979	GD24979. (596 aa)
	DsimGD23703	GD23703. (318 aa)
	DsimGD23692	GD23692. (354 aa)
	DsimGD23691	GD23691. (314 aa)
	DsimGD21801	GD21801. (534 aa)
	DsimGD22316	GD22316. (549 aa)
	DsimGD23096	Dynein light chain. (89 aa)
	DsimGD22924	Adenylyl cyclase-associated protein; Belongs to the CAP family. (786 aa)
	DsimGD23022	GD23022. (700 aa)
	DsimGD23020	GD23020. (410 aa)
	DsimGD23471	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (795 aa)
	DsimGD23007	GD23007. (1088 aa)
	DsimGD23006	GD23006. (1098 aa)
	DsimGD22039	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (377 aa)
	DsimGD23368	GD23368. (689 aa)
	DsimGD23334	GD23334. (728 aa)
	DsimGD24274	GD24274. (710 aa)
	DsimGD24871	GD24871. (203 aa)
	DsimGD24744	GD24744. (96 aa)
	DsimGD24735	GD24735. (429 aa)
	CkIIalpha	Casein kinase II alpha subunit, isoform B; Belongs to the protein kinase superfamily. (336 aa)
	DsimGD17591	GD17591; Belongs to the actin family. (180 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CkIIalpha	N	B4NT68	B4R3W6	Casein kinase II alpha subunit, isoform B; Belongs to the protein kinase superfamily.	Notch.	0.447
Dl	N	B4QTE8	B4R3W6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch.	0.999
DsimGD10603	DsimGD16346	B4QG90	B4R3W0	GD10603.	GD16346.	0.905
DsimGD10603	DsimGD16630	B4QG90	B4R3W5	GD10603.	GD16630.	0.932
DsimGD10603	DsimGD18015	B4QG90	B4QYT9	GD10603.	GD18015.	0.504
DsimGD10605	DsimGD16346	B4QG93	B4R3W0	GD10605.	GD16346.	0.905
DsimGD10605	DsimGD16630	B4QG93	B4R3W5	GD10605.	GD16630.	0.932
DsimGD10605	DsimGD18015	B4QG93	B4QYT9	GD10605.	GD18015.	0.504
DsimGD10920	N	B4QDH2	B4R3W6	GD10920.	Notch.	0.769
DsimGD10921	N	B4QDH3	B4R3W6	GD10921.	Notch.	0.769
DsimGD11239	DsimGD12518	B4QIJ2	B4QLT4	GD11239.	GD12518.	0.945
DsimGD11239	DsimGD14228	B4QIJ2	B4QNR8	GD11239.	GD14228; Belongs to the peptidase C14A family.	0.999
DsimGD11239	DsimGD15668	B4QIJ2	B4R6N6	GD11239.	GD15668.	0.410
DsimGD11239	DsimGD25587	B4QIJ2	B4QH01	GD11239.	GD25587.	0.546
DsimGD11630	DsimGD19397	B4QGL8	B4R145	GD11630.	GD19397.	0.449
DsimGD11849	DsimGD23691	B4QBX1	B4Q986	GD11849.	GD23691.	0.523
DsimGD11849	DsimGD23692	B4QBX1	B4Q987	GD11849.	GD23692.	0.523
DsimGD12147	DsimGD12888	B4QJL8	B4QNQ1	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	GD12888; Belongs to the protein kinase superfamily.	0.995
DsimGD12147	DsimGD14832	B4QJL8	B4QRC0	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	GD14832.	0.997
DsimGD12147	DsimGD20395	B4QJL8	B4QZ73	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	GD20395; Belongs to the cyclin family.	0.993