STRINGSTRING
DsimGD15023 DsimGD15023 DsimGD12613 DsimGD12613 DsimGD11165 DsimGD11165 DsimGD11670 DsimGD11670 DsimGD11571 DsimGD11571 DsimGD10344 DsimGD10344 Dsimbgcn Dsimbgcn DsimGD22755 DsimGD22755 DsimGD22331 DsimGD22331 DsimGD21681 DsimGD21681 DsimGD24645 DsimGD24645 DsimGD23310 DsimGD23310 DsimGD20884 DsimGD20884 DsimGD20882 DsimGD20882 DsimGD18526 DsimGD18526 DsimGD18528 DsimGD18528 DsimGD19029 DsimGD19029 DsimGD20327 DsimGD20327 DsimGD20303 DsimGD20303 DsimGD18681 DsimGD18681 DsimGD19716 DsimGD19716 DsimGD18709 DsimGD18709 DsimGD18751 DsimGD18751 DsimGD20640 DsimGD20640 DsimGD20546 DsimGD20546 DsimGD20545 DsimGD20545 DsimGD14791 DsimGD14791 DsimGD14248 DsimGD14248 DsimGD12898 DsimGD12898 DsimGD14135 DsimGD14135 DsimGD13015 DsimGD13015 DsimGD14056 DsimGD14056 DsimGD16990 DsimGD16990 DsimGD16967 DsimGD16967 mei-218 mei-218 DsimGD17278 DsimGD17278 DsimGD16811 DsimGD16811 DsimGD16747 DsimGD16747 DsimGD16723 DsimGD16723 Mcm3 Mcm3 DsimGD16432 DsimGD16432 DsimGD18916 DsimGD18916 DsimGD19428 DsimGD19428
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD15023GD15023. (695 aa)
DsimGD12613GD12613. (1009 aa)
DsimGD11165GD11165. (161 aa)
DsimGD11670GD11670. (1301 aa)
DsimGD11571GD11571. (769 aa)
DsimGD10344GD10344. (1298 aa)
DsimbgcnBenign gonial cell neoplasm. (354 aa)
DsimGD22755ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (663 aa)
DsimGD22331GD22331. (613 aa)
DsimGD21681GD21681. (939 aa)
DsimGD24645GD24645. (1180 aa)
DsimGD23310GD23310; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (755 aa)
DsimGD20884GD20884. (268 aa)
DsimGD20882Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
DsimGD18526GD18526. (199 aa)
DsimGD18528GD18528; Belongs to the MCM family. (311 aa)
DsimGD19029GD19029. (2182 aa)
DsimGD20327GD20327; Belongs to the MCM family. (883 aa)
DsimGD20303GD20303. (146 aa)
DsimGD18681RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
DsimGD19716GD19716. (758 aa)
DsimGD18709DNA helicase; Belongs to the MCM family. (733 aa)
DsimGD18751GD18751. (631 aa)
DsimGD20640GD20640. (1473 aa)
DsimGD20546GD20546. (967 aa)
DsimGD20545GD20545. (1025 aa)
DsimGD14791RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (481 aa)
DsimGD14248GD14248. (802 aa)
DsimGD12898Nibrin. (812 aa)
DsimGD14135DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (607 aa)
DsimGD13015GD13015. (659 aa)
DsimGD14056GD14056. (1011 aa)
DsimGD16990GD16990. (245 aa)
DsimGD16967GD16967. (1100 aa)
mei-218Mei-218. (236 aa)
DsimGD17278GD17278. (393 aa)
DsimGD16811DNA helicase; Belongs to the MCM family. (817 aa)
DsimGD16747GD16747. (308 aa)
DsimGD16723GD16723. (68 aa)
Mcm3Minichromosome maintenance 3. (264 aa)
DsimGD16432GD16432. (379 aa)
DsimGD18916GD18916. (669 aa)
DsimGD19428GD19428. (1487 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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