(16 nodes) Cellular response to reactive oxygen species network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD25515	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (217 aa)
	DsimGD14531	GD14531. (196 aa)
	DsimGD18318	Mitogen-activated protein kinase. (366 aa)
	DsimGD21244	GD21244. (270 aa)
	DsimGD21547	GD21547. (187 aa)
	DsimGD17115	GD17115. (194 aa)
	Sod1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
	DsimGD26004	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (264 aa)
	DsimGD25801	GD25801. (176 aa)
	DsimGD10833	GD10833. (207 aa)
	DsimGD25903	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (181 aa)
	DsimGD23686	GD23686. (287 aa)
	DsimGD22289	Mitogen-activated protein kinase. (372 aa)
	DsimGD23496	GD23496. (118 aa)
	DsimGD22004	GD22004. (142 aa)
	DsimGD23919	Mitogen-activated protein kinase. (365 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD14531	DsimGD17115	B4QKL4	B4R4B3	GD14531.	GD17115.	0.989
DsimGD14531	DsimGD25515	B4QKL4	B4QIF5	GD14531.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.624
DsimGD17115	DsimGD14531	B4R4B3	B4QKL4	GD17115.	GD14531.	0.989
DsimGD17115	DsimGD25515	B4R4B3	B4QIF5	GD17115.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.624
DsimGD17115	Sod1	B4R4B3	P61852	GD17115.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.	0.449
DsimGD18318	DsimGD22289	B4QSH3	B4Q8R6	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.457
DsimGD18318	DsimGD23919	B4QSH3	B4Q554	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.979
DsimGD21244	DsimGD21547	B4QVG3	B4R2A1	GD21244.	GD21547.	0.698
DsimGD21244	DsimGD25515	B4QVG3	B4QIF5	GD21244.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.981
DsimGD21244	DsimGD25903	B4QVG3	B4QBK9	GD21244.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.915
DsimGD21244	DsimGD26004	B4QVG3	B4QI94	GD21244.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.950
DsimGD21244	Sod1	B4QVG3	P61852	GD21244.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.	0.912
DsimGD21547	DsimGD21244	B4R2A1	B4QVG3	GD21547.	GD21244.	0.698
DsimGD21547	DsimGD25515	B4R2A1	B4QIF5	GD21547.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.813
DsimGD21547	DsimGD25903	B4R2A1	B4QBK9	GD21547.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	0.698
DsimGD21547	Sod1	B4R2A1	P61852	GD21547.	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family.	0.698
DsimGD22289	DsimGD18318	B4Q8R6	B4QSH3	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.457
DsimGD22289	DsimGD23919	B4Q8R6	B4Q554	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.457
DsimGD22289	DsimGD25515	B4Q8R6	B4QIF5	Mitogen-activated protein kinase.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.884
DsimGD23919	DsimGD18318	B4Q554	B4QSH3	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.979