(51 nodes) Regulation of tube size, open tracheal system network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD11990	GD11990. (185 aa)
	DsimGD11989	GD11989. (355 aa)
	DsimGD24716	GD24716. (154 aa)
	DsimGD24626	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (532 aa)
	DsimGD24538	GD24538. (151 aa)
	DsimGD23059	GD23059. (185 aa)
	DsimGD21680	GD21680; Belongs to the MAGUK family. (644 aa)
	DsimGD23827	GD23827. (151 aa)
	DsimGD22574	GD22574. (441 aa)
	DsimGD22540	GD22540. (340 aa)
	DsimGD23035	GD23035. (153 aa)
	DsimGD22944	GD22944. (3038 aa)
	Tep6	Thioester-containing protein 6. (1762 aa)
	DsimGD21942	GD21942. (956 aa)
	DsimGD22860	GD22860. (1011 aa)
	DsimGD22859	GD22859. (101 aa)
	DsimGD22858	GD22858. (53 aa)
	dpp	Dpp. (455 aa)
	DsimGD22290	GD22290. (224 aa)
	DsimGD23256	GD23256. (2814 aa)
	DsimGD22718	GD22718. (3385 aa)
	DsimGD10750	GD10750; Belongs to the G-protein coupled receptor 2 family. (3463 aa)
	DsimGD11322	GD11322. (697 aa)
	DsimGD24926	GD24926. (536 aa)
	DsimGD10381	GD10381. (143 aa)
	DsimGD10855	GD10855. (537 aa)
	DsimGD10856	GD10856. (1202 aa)
	DsimGD10890	GD10890. (173 aa)
	DsimGD11421	GD11421. (780 aa)
	DsimGD11436	GD11436. (1393 aa)
	DsimGD11036	GD11036. (1092 aa)
	DsimGD11601	GD11601. (705 aa)
	DsimGD11158	GD11158. (192 aa)
	DsimGD14489	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family. (415 aa)
	DsimGD12781	GD12781. (158 aa)
	DsimGD12256	GD12256. (594 aa)
	DsimGD12255	GD12255. (541 aa)
	DsimGD14363	GD14363. (1366 aa)
	DsimGD13191	GD13191. (245 aa)
	DsimGD21583	GD21583. (169 aa)
	ttk	GD21596. (813 aa)
	DsimGD19187	GD19187. (169 aa)
	DsimGD20733	GD20733. (689 aa)
	DsimGD18605	GD18605. (258 aa)
	DsimGD19561	GD19561. (258 aa)
	DsimGD19388	Sodium/potassium-transporting ATPase subunit alpha. (1092 aa)
	Fas2	Fasciclin 2. (840 aa)
	sqh	Sqh. (174 aa)
	DsimGD15774	GD15774. (281 aa)
	DsimGD15712	GD15712. (85 aa)
	DsimGD16907	GD16907. (601 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD10381	DsimGD10890	B4QCN5	B4QCX0	GD10381.	GD10890.	0.816
DsimGD10381	DsimGD11436	B4QCN5	B4QDM7	GD10381.	GD11436.	0.589
DsimGD10381	DsimGD12255	B4QCN5	B4QQX6	GD10381.	GD12255.	0.414
DsimGD10381	DsimGD12781	B4QCN5	B4QQA2	GD10381.	GD12781.	0.732
DsimGD10381	DsimGD14363	B4QCN5	B4QR65	GD10381.	GD14363.	0.841
DsimGD10381	DsimGD16907	B4QCN5	B4R6J8	GD10381.	GD16907.	0.725
DsimGD10381	DsimGD18605	B4QCN5	B4QX74	GD10381.	GD18605.	0.893
DsimGD10381	DsimGD19388	B4QCN5	B4R1P5	GD10381.	Sodium/potassium-transporting ATPase subunit alpha.	0.666
DsimGD10381	DsimGD19561	B4QCN5	B4QXN5	GD10381.	GD19561.	0.528
DsimGD10381	DsimGD22540	B4QCN5	B4Q521	GD10381.	GD22540.	0.588
DsimGD10381	DsimGD23035	B4QCN5	B4Q659	GD10381.	GD23035.	0.561
DsimGD10381	DsimGD23827	B4QCN5	B4Q3R7	GD10381.	GD23827.	0.675
DsimGD10381	DsimGD24716	B4QCN5	B4NTU7	GD10381.	GD24716.	0.453
DsimGD10381	Tep6	B4QCN5	B4Q695	GD10381.	Thioester-containing protein 6.	0.584
DsimGD10750	DsimGD14489	B4QAL9	B4QJZ3	GD10750; Belongs to the G-protein coupled receptor 2 family.	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	0.953
DsimGD10750	DsimGD23059	B4QAL9	B4NVY2	GD10750; Belongs to the G-protein coupled receptor 2 family.	GD23059.	0.688
DsimGD10855	DsimGD10856	B4QCS6	B4QCS7	GD10855.	GD10856.	0.921
DsimGD10855	DsimGD21583	B4QCS6	B4QSN3	GD10855.	GD21583.	0.891
DsimGD10855	DsimGD24626	B4QCS6	B4NTW6	GD10855.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.708
DsimGD10856	DsimGD10855	B4QCS7	B4QCS6	GD10856.	GD10855.	0.921