67 items (Drosophila simulans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD18089	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1388 aa)
	DsimGD16281	GD16281. (478 aa)
	DsimGD16852	GD16852. (1734 aa)
	DsimGD15700	GD15700. (407 aa)
	DsimGD15701	GD15701. (428 aa)
	DsimGD17341	GD17341. (829 aa)
	oc	GD16101. (631 aa)
	DsimGD15668	GD15668. (547 aa)
	DsimGD15666	GD15666. (638 aa)
	DsimGD15648	GD15648. (413 aa)
	DsimGD16951	GD16951. (331 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
	DsimGD20292	GD20292. (1075 aa)
	hyd	Hyd. (2749 aa)
	Dl	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (823 aa)
	DsimGD20060	Signal transducer and activator of transcription. (754 aa)
	DsimGD12245	GD12245; Belongs to the protein kinase superfamily. (459 aa)
	DsimGD12719	GD12719. (666 aa)
	DsimGD12350	GD12350. (410 aa)
	DsimGD12903	GD12903. (1459 aa)
	DsimGD12904	GD12904. (375 aa)
	DsimGD12905	GD12905. (1460 aa)
	DsimGD12467	GD12467. (325 aa)
	DsimGD13604	GD13604. (696 aa)
	DsimGD13495	GD13495. (1066 aa)
	DsimGD13498	GD13498. (607 aa)
	DsimGD12518	GD12518. (430 aa)
	DsimGD13499	GD13499. (452 aa)
	DsimGD19135	Mothers against decapentaplegic homolog. (570 aa)
	DsimGD19752	GD19752. (609 aa)
	DsimGD21183	GD21183. (713 aa)
	DsimGD21179	GD21179. (495 aa)
	DsimGD13176	GD13176. (263 aa)
	DsimGD10055	GD10055; Belongs to the protein kinase superfamily. (446 aa)
	DsimGD25595	GD25595. (425 aa)
	DsimGD10620	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (601 aa)
	DsimGD11601	GD11601. (705 aa)
	N	Notch. (811 aa)
	DsimGD11058	GD11058. (1625 aa)
	DsimGD11901	GD11901. (327 aa)
	DsimGD11339	GD11339. (348 aa)
	DsimGD10791	GD10791. (395 aa)
	DsimGD22176	GD22176. (1265 aa)
	DsimGD23776	GD23776. (1270 aa)
	DsimGD24124	GD24124. (741 aa)
	dpp	Dpp. (455 aa)
	DsimGD23109	GD23109. (125 aa)
	chinmo	GD23106. (352 aa)
	DsimGD21910	GD21910. (850 aa)
	DsimGD23020	GD23020. (410 aa)
	DsimGD23013	GD23013; Belongs to the G-protein coupled receptor Fz/Smo family. (1034 aa)
	DsimGD23964	GD23964. (537 aa)
	DsimGD22568	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (771 aa)
	DsimGD24333	GD24333. (954 aa)
	DsimGD24309	GD24309. (775 aa)
	DsimGD24563	GD24563. (547 aa)
	DsimGD15115	GD15115. (389 aa)
	DsimGD15390	GD15390. (298 aa)
	DsimGD15378	GD15378. (538 aa)
	hop	Hop. (524 aa)
	DsimGD24416	GD24416. (342 aa)
	ey	Eyeless. (429 aa)
	pnt	Pnt. (354 aa)
	DsimGD18390	GD18390. (355 aa)
	Axn	Axn. (367 aa)
	DsimGD19430	GD19430. (339 aa)
	DsimGD18530	GD18530. (284 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Axn	DsimGD11601	B4R0Y3	B4QG50	Axn.	GD11601.	0.556
Axn	DsimGD15378	B4R0Y3	B4NSB1	Axn.	GD15378.	0.493
Axn	DsimGD18089	B4R0Y3	B4QXF3	Axn.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.421
Axn	DsimGD23013	B4R0Y3	B4Q616	Axn.	GD23013; Belongs to the G-protein coupled receptor Fz/Smo family.	0.632
Dl	DsimGD18089	B4QTE8	B4QXF3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.694
Dl	N	B4QTE8	B4R3W6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch.	0.999
DsimGD10620	DsimGD19135	B4QGP3	B4QWC3	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.784
DsimGD10620	dpp	B4QGP3	B4Q848	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Dpp.	0.898
DsimGD11601	Axn	B4QG50	B4R0Y3	GD11601.	Axn.	0.556
DsimGD11601	DsimGD11901	B4QG50	B4QCK9	GD11601.	GD11901.	0.414
DsimGD11601	DsimGD12350	B4QG50	B4QPF1	GD11601.	GD12350.	0.614
DsimGD11601	DsimGD12467	B4QG50	B4QMT9	GD11601.	GD12467.	0.994
DsimGD11601	DsimGD15378	B4QG50	B4NSB1	GD11601.	GD15378.	0.588
DsimGD11601	DsimGD15648	B4QG50	B4R6X7	GD11601.	GD15648.	0.490
DsimGD11601	DsimGD18089	B4QG50	B4QXF3	GD11601.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.500
DsimGD11601	DsimGD18390	B4QG50	B4R1F8	GD11601.	GD18390.	0.705
DsimGD11601	DsimGD18530	B4QG50	B4QYN0	GD11601.	GD18530.	0.628
DsimGD11601	DsimGD20060	B4QG50	B4QS27	GD11601.	Signal transducer and activator of transcription.	0.912
DsimGD11601	DsimGD22568	B4QG50	B4Q4Y0	GD11601.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.450
DsimGD11601	DsimGD23013	B4QG50	B4Q616	GD11601.	GD23013; Belongs to the G-protein coupled receptor Fz/Smo family.	0.588