(10 nodes) Site of double-strand break network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD23775	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (620 aa)
	DsimGD24872	GD24872. (211 aa)
	DsimGD19652	Checkpoint protein; Belongs to the HUS1 family. (278 aa)
	DsimGD21310	Histone H2A; Belongs to the histone H2A family. (141 aa)
	DsimGD18880	GD18880. (1140 aa)
	DsimGD11798	GD11798. (652 aa)
	DsimGD20355	GD20355. (204 aa)
	DsimGD15982	GD15982. (112 aa)
	DsimGD12080	GD12080. (889 aa)
	DsimGD18313	GD18313. (1123 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD12080	DsimGD23775	B4QKP6	B4QAD4	GD12080.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.655
DsimGD15982	DsimGD18880	B4R356	B4R1W6	GD15982.	GD18880.	0.646
DsimGD15982	DsimGD19652	B4R356	B4QVM6	GD15982.	Checkpoint protein; Belongs to the HUS1 family.	0.725
DsimGD15982	DsimGD23775	B4R356	B4QAD4	GD15982.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.613
DsimGD18313	DsimGD21310	B4QSI4	B4QWS7	GD18313.	Histone H2A; Belongs to the histone H2A family.	0.474
DsimGD18880	DsimGD15982	B4R1W6	B4R356	GD18880.	GD15982.	0.646
DsimGD19652	DsimGD15982	B4QVM6	B4R356	Checkpoint protein; Belongs to the HUS1 family.	GD15982.	0.725
DsimGD19652	DsimGD23775	B4QVM6	B4QAD4	Checkpoint protein; Belongs to the HUS1 family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.796
DsimGD21310	DsimGD18313	B4QWS7	B4QSI4	Histone H2A; Belongs to the histone H2A family.	GD18313.	0.474
DsimGD23775	DsimGD12080	B4QAD4	B4QKP6	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	GD12080.	0.655
DsimGD23775	DsimGD15982	B4QAD4	B4R356	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	GD15982.	0.613
DsimGD23775	DsimGD19652	B4QAD4	B4QVM6	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Checkpoint protein; Belongs to the HUS1 family.	0.796