(24 nodes) pre-mRNA binding network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD13329	GD13329. (721 aa)
	DsimGD15250	GD15250. (2312 aa)
	DsimGD15247	GD15247. (323 aa)
	DsimGD15246	GD15246. (76 aa)
	DsimGD15074	GD15074. (257 aa)
	DsimGD24670	GD24670. (400 aa)
	DsimGD24751	GD24751. (169 aa)
	DsimGD24494	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (416 aa)
	DsimGD24430	GD24430. (110 aa)
	DsimGD13978	GD13978. (65 aa)
	DsimGD23299	GD23299. (492 aa)
	DsimGD22967	GD22967. (263 aa)
	DsimGD25857	GD25857. (902 aa)
	DsimGD25073	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (445 aa)
	tra	Transformer. (182 aa)
	DsimGD12916	GD12916. (252 aa)
	snRNP-U1-C	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family. (145 aa)
	DsimGD18245	GD18245. (596 aa)
	DsimGD19696	GD19696. (418 aa)
	DsimGD18616	GD18616. (330 aa)
	DsimGD15489	GD15489. (380 aa)
	DsimGD15488	GD15488. (130 aa)
	DsimGD16166	GD16166. (318 aa)
	Sxl	Sex lethal. (301 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD12916	DsimGD22967	B4QN78	B4Q622	GD12916.	GD22967.	0.747
DsimGD12916	DsimGD23299	B4QN78	B4Q326	GD12916.	GD23299.	0.747
DsimGD13329	DsimGD16166	B4QPI5	B4R5X4	GD13329.	GD16166.	0.819
DsimGD13329	DsimGD18245	B4QPI5	B4QU91	GD13329.	GD18245.	0.483
DsimGD13329	Sxl	B4QPI5	B4R5X5	GD13329.	Sex lethal.	0.732
DsimGD15246	DsimGD15250	B4NSF3	B4NSE5	GD15246.	GD15250.	0.924
DsimGD15246	DsimGD19696	B4NSF3	B4QUY3	GD15246.	GD19696.	0.761
DsimGD15246	DsimGD24751	B4NSF3	B4NU20	GD15246.	GD24751.	0.756
DsimGD15246	DsimGD25857	B4NSF3	B4QC84	GD15246.	GD25857.	0.899
DsimGD15246	snRNP-U1-C	B4NSF3	B4QTW7	GD15246.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.494
DsimGD15247	DsimGD19696	B4NSF0	B4QUY3	GD15247.	GD19696.	0.761
DsimGD15247	DsimGD24751	B4NSF0	B4NU20	GD15247.	GD24751.	0.756
DsimGD15247	DsimGD25857	B4NSF0	B4QC84	GD15247.	GD25857.	0.918
DsimGD15247	snRNP-U1-C	B4NSF0	B4QTW7	GD15247.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.494
DsimGD15250	DsimGD15246	B4NSE5	B4NSF3	GD15250.	GD15246.	0.924
DsimGD15250	DsimGD19696	B4NSE5	B4QUY3	GD15250.	GD19696.	0.761
DsimGD15250	DsimGD24751	B4NSE5	B4NU20	GD15250.	GD24751.	0.756
DsimGD15250	snRNP-U1-C	B4NSE5	B4QTW7	GD15250.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.494
DsimGD16166	DsimGD13329	B4R5X4	B4QPI5	GD16166.	GD13329.	0.819
DsimGD16166	DsimGD18245	B4R5X4	B4QU91	GD16166.	GD18245.	0.448