(217 nodes) Chitin-based cuticle development network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD12009	GD12009. (195 aa)
	DsimGD17606	GD17606. (192 aa)
	DsimGD17593	GD17593. (127 aa)
	DsimGD15195	GD15195. (241 aa)
	DsimGD24659	GD24659. (838 aa)
	DsimGD24644	GD24644. (450 aa)
	DsimGD24735	GD24735. (429 aa)
	DsimGD24559	GD24559. (814 aa)
	DsimGD24538	GD24538. (151 aa)
	DsimGD24794	GD24794. (197 aa)
	DsimGD24805	GD24805. (130 aa)
	DsimGD24816	GD24816. (942 aa)
	DsimGD22274	GD10560. (112 aa)
	DsimGD20862	GD20862. (112 aa)
	DsimGD18466	GD18466. (62 aa)
	DsimGD14953	GD14953. (101 aa)
	DsimGD22701	GD22701. (3703 aa)
	DsimGD22700	GD22700. (3314 aa)
	DsimGD22632	GD22632. (249 aa)
	DsimGD22574	GD22574. (441 aa)
	DsimGD22030	GD22030. (95 aa)
	DsimGD22029	GD22029. (255 aa)
	DsimGD22028	GD22028. (237 aa)
	DsimGD23446	GD23446. (184 aa)
	DsimGD22005	GD22005. (216 aa)
	DsimGD22996	GD22996. (1161 aa)
	DsimGD22473	GD22473. (135 aa)
	DsimGD22471	GD22471. (145 aa)
	DsimGD22462	GD22462. (197 aa)
	DsimGD22423	GD22423. (326 aa)
	Idgf1	Imaginal disc growth factor 1. (385 aa)
	Idgf3	Imaginal disc growth factor 3; Belongs to the glycosyl hydrolase 18 family. (441 aa)
	DsimGD23089	GD23089. (691 aa)
	DsimGD23563	GD23563. (489 aa)
	DsimGD23612	GD23612. (153 aa)
	DsimGD22860	GD22860. (1011 aa)
	DsimGD22859	GD22859. (101 aa)
	DsimGD22858	GD22858. (53 aa)
	DsimGD23152	GD23152. (519 aa)
	DsimGD22323	GD22323. (146 aa)
	DsimGD22800	GD22800. (1466 aa)
	DsimGD23185	GD23185. (310 aa)
	DsimGD23654	GD23654. (341 aa)
	DsimGD23688	Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (410 aa)
	amd	Alpha methyl dopa-resistant, isoform A. (510 aa)
	DsimGD21743	GD21743. (447 aa)
	DsimGD22721	GD22721. (628 aa)
	DsimGD22720	GD22720. (118 aa)
	DsimGD25483	GD25483. (328 aa)
	DsimGD10782	GD10782. (214 aa)
	DsimGD25932	GD25932. (131 aa)
	DsimGD25931	GD25931. (117 aa)
	DsimGD25930	GD25930. (617 aa)
	DsimGD25926	GD25926. (117 aa)
	DsimGD11815	GD11815. (130 aa)
	DsimGD25881	GD25881. (198 aa)
	DsimGD11322	GD11322. (697 aa)
	DsimGD24954	GD24954. (520 aa)
	DsimGD10372	GD10372. (461 aa)
	DsimGD10373	GD10373. (262 aa)
	DsimGD10374	GD10374; Belongs to the multicopper oxidase family. (159 aa)
	DsimGD11369	GD11369; Belongs to the glycosyl hydrolase 18 family. (443 aa)
	DsimGD24931	GD24931. (93 aa)
	DsimGD10334	GD10334. (882 aa)
	DsimGD10870	GD10870. (267 aa)
	DsimGD10871	GD10871. (220 aa)
	DsimGD10873	GD10873. (253 aa)
	DsimGD25846	GD25846. (166 aa)
	DsimGD10877	GD10877. (134 aa)
	DsimGD10878	GD10878. (126 aa)
	DsimGD10879	GD10879. (134 aa)
	DsimGD10883	GD10883. (190 aa)
	DsimGD10939	GD10939. (698 aa)
	DsimGD10982	GD10982. (826 aa)
	DsimGD10983	GD10983. (178 aa)
	DsimGD25273	GD25273. (186 aa)
	DsimGD25230	GD25230. (323 aa)
	DsimGD25228	GD25228; Belongs to the glycosyl hydrolase 18 family. (368 aa)
	DsimGD11572	GD11572. (273 aa)
	DsimGD10171	GD10171. (130 aa)
	DsimGD10559	GD10559. (112 aa)
	DsimGD25677	GD25677. (144 aa)
	DsimGD11123	GD11123. (735 aa)
	DsimGD11213	GD11213; Belongs to the glycosyl hydrolase 18 family. (452 aa)
	DsimGD11218	GD11218. (609 aa)
	DsimGD13154	GD13154. (558 aa)
	DsimGD13153	GD13153. (105 aa)
	DsimGD13152	GD13152. (106 aa)
	DsimGD13151	GD13150. (105 aa)
	DsimGD13149	GD13149. (67 aa)
	DsimGD13147	GD13147. (111 aa)
	DsimGD13146	GD13146. (108 aa)
	DsimGD13938	GD13938. (108 aa)
	DsimGD13939	GD13939. (107 aa)
	DsimGD13940	GD13940. (104 aa)
	DsimGD13941	GD13941. (104 aa)
	DsimGD13942	GD13942. (104 aa)
	DsimGD13145	GD13145. (98 aa)
	DsimGD13943	GD13943. (102 aa)
	DsimGD13144	GD13144. (105 aa)
	DsimGD13142	GD13142. (109 aa)
	DsimGD12127	GD12127. (126 aa)
	DsimGD14947	GD14947. (140 aa)
	DsimGD12126	GD12126. (122 aa)
	DsimGD14949	GD14949. (120 aa)
	DsimGD13091	GD13091. (179 aa)
	DsimGD13990	GD13990. (127 aa)
	DsimGD14489	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family. (415 aa)
	DsimGD12099	GD12099. (137 aa)
	DsimGD15013	GD15013. (986 aa)
	DsimGD14552	GD14552. (516 aa)
	DsimGD14077	GD14077. (263 aa)
	DsimGD14078	GD14078. (177 aa)
	DsimGD14080	GD14080. (307 aa)
	DsimGD14081	GD14081. (162 aa)
	DsimGD14115	GD14115. (270 aa)
	DsimGD12967	GD12967. (244 aa)
	DsimGD14633	GD14633. (341 aa)
	DsimGD14634	GD14634. (216 aa)
	DsimGD12478	GD12478. (438 aa)
	DsimGD13442	GD13442; Belongs to the glycosyl hydrolase 18 family. (484 aa)
	DsimGD12468	GD12468. (851 aa)
	DsimGD13435	GD13435. (136 aa)
	DsimGD13434	GD13434. (180 aa)
	DsimGD13400	GD13400. (240 aa)
	DsimGD14178	GD14178. (259 aa)
	DsimGD12437	GD12437. (410 aa)
	DsimGD12434	GD12434. (1012 aa)
	DsimGD13359	GD13359; Belongs to the glycosyl hydrolase 18 family. (1013 aa)
	DsimGD14264	GD14264. (134 aa)
	DsimGD14265	GD14265. (134 aa)
	DsimGD14266	GD14266. (116 aa)
	DsimGD13808	GD13808; Belongs to the cytochrome P450 family. (489 aa)
	DsimGD12297	GD12297; Belongs to the G-protein coupled receptor Fz/Smo family. (693 aa)
	DsimGD13280	GD13280. (195 aa)
	DsimGD13279	GD13279. (147 aa)
	DsimGD13278	GD13278. (188 aa)
	DsimGD13823	GD13823. (247 aa)
	DsimGD12275	GD12275. (205 aa)
	DsimGD14807	GD14807. (198 aa)
	DsimGD14808	GD14808. (424 aa)
	DsimGD14810	GD14810. (648 aa)
	DsimGD12256	GD12256. (594 aa)
	DsimGD12255	GD12255. (541 aa)
	DsimGD13850	GD13850. (732 aa)
	DsimGD13229	GD13229. (2433 aa)
	DsimGD13231	GD13231. (848 aa)
	DsimGD21072	GD21072. (1067 aa)
	DsimGD21583	GD21583. (169 aa)
	DsimGD18306	GD18306; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1314 aa)
	ttk	GD21596. (813 aa)
	DsimGD20110	GD20110. (211 aa)
	DsimGD19709	GD19709. (357 aa)
	DsimGD19694	GD19694. (278 aa)
	DsimGD19711	GD19711. (255 aa)
	DsimGD20733	GD20733. (689 aa)
	DsimGD20247	GD20247. (303 aa)
	DsimGD21291	GD21291. (275 aa)
	DsimGD18131	GD18131. (220 aa)
	DsimGD18130	GD18130. (286 aa)
	DsimGD18128	GD18128. (229 aa)
	DsimGD18127	GD18127. (247 aa)
	DsimGD21292	GD21292. (274 aa)
	DsimGD21293	GD21293. (309 aa)
	DsimGD21294	GD21294. (241 aa)
	DsimGD21295	GD21295. (315 aa)
	DsimGD21296	GD21296. (228 aa)
	DsimGD21297	GD21297. (256 aa)
	DsimGD21298	GD21298. (284 aa)
	DsimGD18124	GD18124. (245 aa)
	DsimGD21319	GD21319. (360 aa)
	DsimGD19805	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (156 aa)
	DsimGD19806	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (479 aa)
	DsimGD18097	GD18097. (235 aa)
	DsimGD19561	GD19561. (258 aa)
	DsimGD19888	GD19888. (188 aa)
	DsimGD19890	GD19890. (191 aa)
	DsimGD18513	GD18513. (482 aa)
	DsimGD18014	GD18014. (245 aa)
	DsimGD18013	GD18013. (2135 aa)
	DsimGD19531	GD19531. (151 aa)
	DsimGD19891	GD19891. (193 aa)
	DsimGD19528	GD19528. (217 aa)
	DsimGD19526	GD19526. (236 aa)
	DsimGD19892	GD19892. (76 aa)
	Gld	Glucose dehydrogenase. (246 aa)
	DsimGD20936	GD20936; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	DsimGD18929	GD18929; Belongs to the glycosyl hydrolase 18 family. (565 aa)
	DsimGD21480	GD21480. (123 aa)
	Axn	Axn. (367 aa)
	DsimGD19409	GD19409. (738 aa)
	DsimGD21013	GD21013; Belongs to the WD repeat SEC13 family. (356 aa)
	DsimGD19366	GD19366. (381 aa)
	DsimGD18373	GD18373. (699 aa)
	DsimGD18370	GD18370. (695 aa)
	DsimGD18369	GD18369. (629 aa)
	pan	Pan. (500 aa)
	DsimGD24381	GD24381. (549 aa)
	DsimGD16405	GD16405. (169 aa)
	DsimGD16374	GD16374. (268 aa)
	DsimGD17081	GD17081. (236 aa)
	DsimGD17103	GD17103. (750 aa)
	DsimGD17132	GD17132. (173 aa)
	DsimGD16755	GD16755. (145 aa)
	DsimGD17195	GD17195. (124 aa)
	DsimGD17302	GD17302. (346 aa)
	DsimGD17303	GD17303. (336 aa)
	DsimGD17305	GD17305. (405 aa)
	DsimGD16887	GD16887. (512 aa)
	DsimGD17347	GD17347. (730 aa)
	DsimGD16489	GD16489. (977 aa)
	DsimGD16065	GD16065. (1626 aa)
	DsimGD16064	GD16064. (189 aa)
	DsimGD17448	GD17448. (91 aa)
	DsimGD15573	GD15573. (721 aa)
	DsimGD17449	GD17449. (714 aa)
	DsimGD25285	GD25285. (215 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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Export your current network:

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file format is 'PNG': portable network graphic

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Axn	DsimGD12297	B4R0Y3	B4QQD4	Axn.	GD12297; Belongs to the G-protein coupled receptor Fz/Smo family.	0.799
Axn	DsimGD14489	B4R0Y3	B4QJZ3	Axn.	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	0.944
Axn	DsimGD16064	B4R0Y3	B4R739	Axn.	GD16064.	0.508
Axn	DsimGD16065	B4R0Y3	B4R738	Axn.	GD16065.	0.508
Axn	DsimGD16405	B4R0Y3	B4R322	Axn.	GD16405.	0.992
Axn	DsimGD18013	B4R0Y3	B4QYU1	Axn.	GD18013.	0.935
Axn	DsimGD18014	B4R0Y3	B4QYU0	Axn.	GD18014.	0.935
Axn	DsimGD20862	B4R0Y3	B4NVA0	Axn.	GD20862.	0.508
Axn	DsimGD21072	B4R0Y3	B4QSH8	Axn.	GD21072.	0.999
Axn	DsimGD24381	B4R0Y3	B4R2F2	Axn.	GD24381.	0.597
Axn	DsimGD24659	B4R0Y3	B4NTQ2	Axn.	GD24659.	0.508
Axn	DsimGD24735	B4R0Y3	B4NTZ2	Axn.	GD24735.	0.998
Axn	pan	B4R0Y3	B4R2D3	Axn.	Pan.	0.831
DsimGD10171	DsimGD10879	B4QFR3	B4QCV2	GD10171.	GD10879.	0.567
DsimGD10171	DsimGD10983	B4QFR3	B4QEH3	GD10171.	GD10983.	0.569
DsimGD10171	DsimGD12099	B4QFR3	B4QK84	GD10171.	GD12099.	0.473
DsimGD10171	DsimGD12275	B4QFR3	B4QQU1	GD10171.	GD12275.	0.470
DsimGD10171	DsimGD13144	B4QFR3	B4QJB2	GD10171.	GD13144.	0.540
DsimGD10171	DsimGD13145	B4QFR3	B4QJB0	GD10171.	GD13145.	0.570
DsimGD10171	DsimGD13146	B4QFR3	B4QJA4	GD10171.	GD13146.	0.495