STRINGSTRING
DsimGD21076 DsimGD21076 DsimGD20584 DsimGD20584 DsimGD18309 DsimGD18309 DsimGD21115 DsimGD21115 DsimGD20154 DsimGD20154 DsimGD18195 DsimGD18195 DsimGD18194 DsimGD18194 DsimGD19182 DsimGD19182 DsimGD20735 DsimGD20735 DsimGD19640 DsimGD19640 DsimGD20776 DsimGD20776 DsimGD19615 DsimGD19615 DsimGD19083 DsimGD19083 DsimGD20305 DsimGD20305 HP1E HP1E DsimGD18601 DsimGD18601 DsimGD20811 DsimGD20811 DsimGD19581 DsimGD19581 DsimGD19053 DsimGD19053 DsimGD18065 DsimGD18065 DsimGD19874 DsimGD19874 DsimGD13565 DsimGD13565 DsimGD17145 DsimGD17145 DsimGD17637 DsimGD17637 DsimGD18178 DsimGD18178 DsimGD13409 DsimGD13409 DsimGD13377 DsimGD13377 DsimGD20105 DsimGD20105 DsimGD21515 DsimGD21515 Nup153 Nup153 DsimGD22697 DsimGD22697 DsimGD23295 DsimGD23295 DsimGD22153 DsimGD22153 DsimGD23804 DsimGD23804 Mt2 Mt2 DsimGD23867 DsimGD23867 DsimGD22084 DsimGD22084 DsimGD24323 DsimGD24323 loqs loqs DsimGD22526 DsimGD22526 DsimGD23471 DsimGD23471 DsimGD23542 DsimGD23542 DsimGD23648 DsimGD23648 DsimGD23161 DsimGD23161 DsimGD22206 DsimGD22206 DsimGD22205 DsimGD22205 Top2 Top2 DsimGD10745 DsimGD10745 Dcr-2 Dcr-2 DsimGD11840 DsimGD11840 DsimGD11841 DsimGD11841 DsimGD11842 DsimGD11842 DsimGD10819 DsimGD10819 DsimGD25412 DsimGD25412 DsimGD10828 DsimGD10828 DsimGD11380 DsimGD11380 DsimGD24920 DsimGD24920 DsimGD11905 DsimGD11905 DsimGD10345 DsimGD10345 DsimGD10344 DsimGD10344 DsimGD11921 DsimGD11921 DsimGD11435 DsimGD11435 DsimGD25796 DsimGD25796 DsimGD10936 DsimGD10936 DsimGD11454 DsimGD11454 cid cid AGO1 AGO1 DsimGD25675 DsimGD25675 DsimGD25670 DsimGD25670 DsimGD25207 DsimGD25207 calypso calypso DsimGD25058 DsimGD25058 DsimGD14471 DsimGD14471 DsimGD12604 DsimGD12604 DsimGD13066 DsimGD13066 DsimGD13065 DsimGD13065 AGO2 AGO2 DsimGD14555 DsimGD14555 DsimGD13605 DsimGD13605 DsimGD12921 DsimGD12921 DsimGD12857 DsimGD12857 DsimGD14262 DsimGD14262 SuUR SuUR DsimGD12830 DsimGD12830 DsimGD14791 DsimGD14791 DsimGD12268 DsimGD12268 e(y)2 e(y)2 DsimGD17589 DsimGD17589 DsimGD17732 DsimGD17732 DsimGD17708 DsimGD17708 DsimGD15403 DsimGD15403 DsimGD15401 DsimGD15401 DsimGD15248 DsimGD15248 DsimGD15288 DsimGD15288 DsimGD12124 DsimGD12124 DsimGD13090 DsimGD13090 DsimGD21818 DsimGD21818 DsimGD24355 DsimGD24355 DsimGD19875 DsimGD19875 DsimGD20365 DsimGD20365 Cen190 Cen190 DsimGD20371 DsimGD20371 DsimGD18995 DsimGD18995 DsimGD20429 DsimGD20429 DsimGD20430 DsimGD20430 DsimGD19447 DsimGD19447 HP1C HP1C DsimGD19999 DsimGD19999 DsimGD18892 DsimGD18892 pho pho DsimGD17501 DsimGD17501 z z DsimGD15945 DsimGD15945 DsimGD16322 DsimGD16322 DsimGD16280 DsimGD16280 DsimGD16166 DsimGD16166 Sxl Sxl DsimGD16466 DsimGD16466 r2d2 r2d2 Rpd3 Rpd3 DsimGD12239 DsimGD12239 DsimGD14861 DsimGD14861 DsimGD21054 DsimGD21054 DsimGD21055 DsimGD21055
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD21076GD21076. (866 aa)
DsimGD20584GD20584. (309 aa)
DsimGD18309GD18309. (969 aa)
DsimGD21115GD21115. (350 aa)
DsimGD20154GD20154. (1621 aa)
DsimGD18195GD18195. (212 aa)
DsimGD18194GD18194. (1098 aa)
DsimGD19182GD19182. (101 aa)
DsimGD20735GD20735. (682 aa)
DsimGD19640GD19640. (633 aa)
DsimGD20776GD20776. (381 aa)
DsimGD19615Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (438 aa)
DsimGD19083GD19083. (914 aa)
DsimGD20305Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (150 aa)
HP1EGD18604. (176 aa)
DsimGD18601GD18601. (242 aa)
DsimGD20811GD20811. (195 aa)
DsimGD19581Histone acetyltransferase type B catalytic subunit. (404 aa)
DsimGD19053GD19053. (840 aa)
DsimGD18065GD18065. (436 aa)
DsimGD19874Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1838 aa)
DsimGD13565GD13565. (256 aa)
DsimGD17145GD17145. (156 aa)
DsimGD17637GD14743. (256 aa)
DsimGD18178GD18178. (205 aa)
DsimGD13409GD13409. (206 aa)
DsimGD13377GD13377. (169 aa)
DsimGD20105GD20105. (138 aa)
DsimGD21515GD21515. (59 aa)
Nup153Nup153. (238 aa)
DsimGD22697GD22697. (363 aa)
DsimGD23295GD23295. (379 aa)
DsimGD22153GD22153. (425 aa)
DsimGD23804GD23804. (462 aa)
Mt2GD23816; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (345 aa)
DsimGD23867GD23867. (826 aa)
DsimGD22084GD22084. (1257 aa)
DsimGD24323GD24323. (189 aa)
loqsLoquacious, isoform A. (464 aa)
DsimGD22526GD22526. (227 aa)
DsimGD23471Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (795 aa)
DsimGD23542GD23542. (129 aa)
DsimGD23648GD23648. (602 aa)
DsimGD23161GD23161. (381 aa)
DsimGD22206GD22206; Belongs to the argonaute family. (843 aa)
DsimGD22205GD22205; Belongs to the argonaute family. (857 aa)
Top2DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1133 aa)
DsimGD10745GD10745. (844 aa)
Dcr-2Dcr-2; Belongs to the helicase family. Dicer subfamily. (1666 aa)
DsimGD11840GD11840. (1630 aa)
DsimGD11841GD11841. (349 aa)
DsimGD11842GD11842. (94 aa)
DsimGD10819GD10819. (76 aa)
DsimGD25412GD25412. (127 aa)
DsimGD10828GD10828. (1128 aa)
DsimGD11380GD11380. (1302 aa)
DsimGD24920GD24920. (109 aa)
DsimGD11905GD11905. (381 aa)
DsimGD10345GD10345. (1443 aa)
DsimGD10344GD10344. (1298 aa)
DsimGD11921GD11921. (498 aa)
DsimGD11435Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (356 aa)
DsimGD25796GD25796. (324 aa)
DsimGD10936GD10936. (138 aa)
DsimGD11454GD11454. (881 aa)
cidCid. (225 aa)
AGO1Argonaute 1. (447 aa)
DsimGD25675GD25675; Belongs to the intermediate filament family. (621 aa)
DsimGD25670GD25670. (2639 aa)
DsimGD25207GD25207. (540 aa)
calypsoUbiquitin carboxyl-terminal hydrolase calypso; Polycomb group (PcG) protein. Catalytic component of the PR- DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-118' (H2AK118ub1). Does not deubiquitinate monoubiquitinated histone H2B. Required to maintain the transcriptionally repressive state of homeotic genes throughout development. The PR-DUB complex has weak or no activity toward 'Lys- 48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). Belongs to the peptidase C12 family. BAP1 subfamily. (471 aa)
DsimGD25058GD25058. (1482 aa)
DsimGD14471GD14471. (1941 aa)
DsimGD12604GD12604. (500 aa)
DsimGD13066GD13066. (474 aa)
DsimGD13065GD13065. (250 aa)
AGO2AGO2. (759 aa)
DsimGD14555GD14555. (2136 aa)
DsimGD13605GD13605. (329 aa)
DsimGD12921GD12921. (669 aa)
DsimGD12857GD12857. (675 aa)
DsimGD14262GD14262. (816 aa)
SuURGD14278. (954 aa)
DsimGD12830Non-specific serine/threonine protein kinase. (1209 aa)
DsimGD14791RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (481 aa)
DsimGD12268GD12268. (2208 aa)
e(y)2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (101 aa)
DsimGD17589GD17589. (342 aa)
DsimGD17732GD17732. (290 aa)
DsimGD17708GD17708. (322 aa)
DsimGD15403GD15403. (499 aa)
DsimGD15401GD15401. (635 aa)
DsimGD15248GD15248. (1012 aa)
DsimGD15288GD15288. (435 aa)
DsimGD12124GD12124. (390 aa)
DsimGD13090Male-specific lethal 3. (512 aa)
DsimGD21818GD21818. (1044 aa)
DsimGD24355GD24355. (259 aa)
DsimGD19875GD19875. (336 aa)
DsimGD20365GD20365. (424 aa)
Cen190Cen190. (498 aa)
DsimGD20371GD20371; Belongs to the PI3/PI4-kinase family. (2694 aa)
DsimGD18995GD18995. (430 aa)
DsimGD20429GD20429. (759 aa)
DsimGD20430GD20430. (153 aa)
DsimGD19447Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1252 aa)
HP1CGD20982. (237 aa)
DsimGD19999GD19999. (391 aa)
DsimGD18892GD18892. (1215 aa)
phoPho. (521 aa)
DsimGD17501GD17501. (261 aa)
zZeste. (573 aa)
DsimGD15945GD15945; Belongs to the peptidase C19 family. (1129 aa)
DsimGD16322GD16322. (696 aa)
DsimGD16280GD16280. (390 aa)
DsimGD16166GD16166. (318 aa)
SxlSex lethal. (301 aa)
DsimGD16466GD16466. (1021 aa)
r2d2R2D2. (311 aa)
Rpd3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (521 aa)
DsimGD12239GD12239. (783 aa)
DsimGD14861Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. (808 aa)
DsimGD21054GD21054. (431 aa)
DsimGD21055GD21055; Belongs to the MT-A70-like family. (154 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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