(38 nodes) Negative regulation of Notch signaling pathway network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD25679	GD25679. (439 aa)
	DsimGD14509	GD14509. (64 aa)
	DsimGD14510	GD14510. (59 aa)
	DsimGD14511	GD14511. (81 aa)
	DsimGD14513	GD14513. (149 aa)
	DsimGD15071	GD15071. (313 aa)
	DsimGD14094	GD14094. (596 aa)
	malpha	Enhancer of split malpha protein. (140 aa)
	m6	Enhancer of split m6 protein. (70 aa)
	DsimGD16124	GD16124. (87 aa)
	DsimGD16809	GD16809. (1691 aa)
	DsimGD16802	GD16802. (734 aa)
	DsimGD20983	GD20983; Belongs to the peptidase C19 family. (364 aa)
	DsimGD18424	GD18424. (411 aa)
	m4	M4. (151 aa)
	DsimGD18236	GD18236. (511 aa)
	DsimGD16195	GD16195. (341 aa)
	DsimGD21088	GD21088. (2287 aa)
	DsimGD19363	GD19363. (653 aa)
	DsimGD12389	GD12389. (267 aa)
	DsimGD14716	GD14716. (700 aa)
	DsimGD14715	GD14715. (249 aa)
	DsimGD13385	GD13385. (1165 aa)
	DsimGD19699	GD19699. (120 aa)
	DsimGD21654	GD21654. (606 aa)
	DsimGD21653	GD21653. (484 aa)
	DsimGD23884	GD23884. (696 aa)
	DsimGD22520	GD22520. (1006 aa)
	DsimGD22519	GD22519. (2395 aa)
	DsimGD22996	GD22996. (1161 aa)
	Su(H)	Su(H). (594 aa)
	DsimGD22949	GD22949. (483 aa)
	DsimGD23128	E3 ubiquitin-protein ligase. (949 aa)
	DsimGD23607	GD23607. (556 aa)
	DsimGD22821	GD22821. (376 aa)
	DsimGD23762	GD23762. (836 aa)
	DsimGD25475	GD25475. (180 aa)
	DsimGD24921	GD24921. (1252 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD12389	DsimGD14715	B4QNX9	B4QNW5	GD12389.	GD14715.	0.713
DsimGD12389	DsimGD14716	B4QNX9	B4QNW6	GD12389.	GD14716.	0.713
DsimGD12389	DsimGD19699	B4QNX9	B4NVG3	GD12389.	GD19699.	0.713
DsimGD12389	DsimGD23128	B4QNX9	B4Q7L9	GD12389.	E3 ubiquitin-protein ligase.	0.774
DsimGD14094	DsimGD14715	B4QM23	B4QNW5	GD14094.	GD14715.	0.452
DsimGD14094	DsimGD14716	B4QM23	B4QNW6	GD14094.	GD14716.	0.942
DsimGD14094	DsimGD16124	B4QM23	B4R6G7	GD14094.	GD16124.	0.937
DsimGD14094	DsimGD19699	B4QM23	B4NVG3	GD14094.	GD19699.	0.452
DsimGD14094	DsimGD23128	B4QM23	B4Q7L9	GD14094.	E3 ubiquitin-protein ligase.	0.923
DsimGD14094	DsimGD24921	B4QM23	B4QCJ6	GD14094.	GD24921.	0.940
DsimGD14509	DsimGD14511	B4QKH2	B4QKH4	GD14509.	GD14511.	0.924
DsimGD14509	m4	B4QKH2	B4QW14	GD14509.	M4.	0.581
DsimGD14510	DsimGD14511	B4QKH3	B4QKH4	GD14510.	GD14511.	0.924
DsimGD14510	m4	B4QKH3	B4QW14	GD14510.	M4.	0.581
DsimGD14511	DsimGD14509	B4QKH4	B4QKH2	GD14511.	GD14509.	0.924
DsimGD14511	DsimGD14510	B4QKH4	B4QKH3	GD14511.	GD14510.	0.924
DsimGD14511	DsimGD14513	B4QKH4	B4QKH6	GD14511.	GD14513.	0.774
DsimGD14511	m4	B4QKH4	B4QW14	GD14511.	M4.	0.966
DsimGD14511	m6	B4QKH4	Q5S405	GD14511.	Enhancer of split m6 protein.	0.596
DsimGD14511	malpha	B4QKH4	Q5S410	GD14511.	Enhancer of split malpha protein.	0.731