(46 nodes) Positive regulation of cell size network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD20399	GD20399. (1467 aa)
	DsimGD17740	GD17740; Belongs to the TCTP family. (95 aa)
	DsimGD11927	GD11927; Belongs to the TCTP family. (572 aa)
	lic	Licorne. (334 aa)
	DsimGD24463	GD24463. (789 aa)
	DsimGD10031	GD10031; Belongs to the TCTP family. (143 aa)
	DsimGD23862	GD23862; Belongs to the PI3/PI4-kinase family. (2168 aa)
	DsimGD23919	Mitogen-activated protein kinase. (365 aa)
	Sos	Sos. (1595 aa)
	DsimGD22513	GD22513. (405 aa)
	DsimGD22512	GD22512; Belongs to the PDGF/VEGF growth factor family. (477 aa)
	DsimGD22511	GD22511. (405 aa)
	DsimGD22428	Receptor protein-tyrosine kinase. (1215 aa)
	DsimGD22427	GD22427. (196 aa)
	DsimGD23137	GD23137. (867 aa)
	DsimGD22290	GD22290. (224 aa)
	DsimGD24240	GD24240. (280 aa)
	DsimGD11434	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (1165 aa)
	drk	Drk. (182 aa)
	DsimGD10530	GD10530; Belongs to the WD repeat SEC13 family. (354 aa)
	DsimGD13175	GD13175. (533 aa)
	DsimGD13174	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (517 aa)
	DsimGD13545	GD13545. (815 aa)
	DsimGD14555	GD14555. (2136 aa)
	DsimGD14218	Insulin-like peptide 2. (137 aa)
	DsimGD13735	GD13735. (1381 aa)
	DsimGD12194	GD12194. (439 aa)
	DsimGD20048	GD20048; Belongs to the PI3/PI4-kinase family. (1079 aa)
	Desat1	Fad; Belongs to the fatty acid desaturase type 1 family. (383 aa)
	DsimGD18318	Mitogen-activated protein kinase. (366 aa)
	DsimGD21576	GD21576. (1567 aa)
	DsimGD20154	GD20154. (1621 aa)
	DsimGD18736	GD18736; Belongs to the TCTP family. (172 aa)
	ksr	Ksr. (967 aa)
	DsimGD19794	GD19794. (182 aa)
	DsimGD19074	Non-specific serine/threonine protein kinase. (530 aa)
	DsimGD20397	GD20397. (212 aa)
	DsimGD19491	GD19491. (320 aa)
	DsimGD20398	GD20398. (1091 aa)
	DsimGD19971	GD19971. (1814 aa)
	DsimGD19972	GD19972. (270 aa)
	DsimGD16640	GD16640. (549 aa)
	DsimGD16235	GD16235; Belongs to the protein kinase superfamily. (331 aa)
	DsimGD16213	GD16213. (1161 aa)
	DsimGD16055	GD16055. (313 aa)
	Ras85D	Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD10530	DsimGD16055	B4QF83	B4R751	GD10530; Belongs to the WD repeat SEC13 family.	GD16055.	0.538
DsimGD10530	DsimGD16213	B4QF83	B4R5C8	GD10530; Belongs to the WD repeat SEC13 family.	GD16213.	0.568
DsimGD10530	DsimGD19794	B4QF83	B4QWX8	GD10530; Belongs to the WD repeat SEC13 family.	GD19794.	0.403
DsimGD10530	DsimGD23137	B4QF83	B4Q7P3	GD10530; Belongs to the WD repeat SEC13 family.	GD23137.	0.999
DsimGD11434	DsimGD19794	B4QDM5	B4QWX8	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	GD19794.	0.582
DsimGD11434	drk	B4QDM5	B4QEE6	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	Drk.	0.657
DsimGD12194	DsimGD13545	B4QRY5	B4QKS8	GD12194.	GD13545.	0.626
DsimGD12194	DsimGD16055	B4QRY5	B4R751	GD12194.	GD16055.	0.523
DsimGD12194	DsimGD16213	B4QRY5	B4R5C8	GD12194.	GD16213.	0.636
DsimGD12194	DsimGD19074	B4QRY5	B4QXQ5	GD12194.	Non-specific serine/threonine protein kinase.	0.958
DsimGD12194	DsimGD19794	B4QRY5	B4QWX8	GD12194.	GD19794.	0.541
DsimGD12194	DsimGD23862	B4QRY5	B4Q4A9	GD12194.	GD23862; Belongs to the PI3/PI4-kinase family.	0.621
DsimGD13174	DsimGD13545	B4QIS8	B4QKS8	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	GD13545.	0.978
DsimGD13174	DsimGD14218	B4QIS8	B4QNP5	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Insulin-like peptide 2.	0.507
DsimGD13174	DsimGD16055	B4QIS8	B4R751	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	GD16055.	0.984
DsimGD13174	DsimGD16213	B4QIS8	B4R5C8	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	GD16213.	0.998
DsimGD13174	DsimGD16640	B4QIS8	B4R3Y1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	GD16640.	0.607
DsimGD13174	DsimGD18318	B4QIS8	B4QSH3	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Mitogen-activated protein kinase.	0.636
DsimGD13174	DsimGD19074	B4QIS8	B4QXQ5	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Non-specific serine/threonine protein kinase.	0.852
DsimGD13174	DsimGD19794	B4QIS8	B4QWX8	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	GD19794.	0.957