STRINGSTRING
DsimGD22283 DsimGD22283 DsimGD24140 DsimGD24140 DsimGD22386 DsimGD22386 DsimGD23110 DsimGD23110 DsimGD22427 DsimGD22427 DsimGD22428 DsimGD22428 DsimGD23499 DsimGD23499 DsimGD23022 DsimGD23022 DsimGD23452 DsimGD23452 DsimGD22052 DsimGD22052 DsimGD24317 DsimGD24317 DsimGD23817 DsimGD23817 DsimGD14194 DsimGD14194 DsimGD12853 DsimGD12853 DsimGD21412 DsimGD21412 DsimGD24573 DsimGD24573 DsimGD24735 DsimGD24735 DsimGD17149 DsimGD17149 DsimGD17456 DsimGD17456 DsimGD16521 DsimGD16521 DsimGD17412 DsimGD17412 DsimGD16124 DsimGD16124 DsimGD17230 DsimGD17230 DsimGD16235 DsimGD16235 DsimGD16321 DsimGD16321 Tak1 Tak1 DsimGD21040 DsimGD21040 DsimGD21039 DsimGD21039 DsimGD18919 DsimGD18919 DsimGD20464 DsimGD20464 DsimGD21442 DsimGD21442 DsimGD18469 DsimGD18469 DsimGD18542 DsimGD18542 DsimGD18063 DsimGD18063 DsimGD19618 DsimGD19618 DsimGD18681 DsimGD18681 DsimGD18194 DsimGD18194 DsimGD18195 DsimGD18195 DsimGD20154 DsimGD20154 DsimGD19320 DsimGD19320 DsimGD16381 DsimGD16381 DsimGD13202 DsimGD13202 DsimGD13332 DsimGD13332 DsimGD13333 DsimGD13333 DsimGD12346 DsimGD12346 DsimGD13355 DsimGD13355 DsimGD13480 DsimGD13480 DsimGD13487 DsimGD13487 DsimGD13597 DsimGD13597 DsimGD12518 DsimGD12518 DsimGD13029 DsimGD13029 Urm1 Urm1 DsimGD12138 DsimGD12138 DsimGD13141 DsimGD13141 Atg9 Atg9 DsimGD10659 DsimGD10659 DsimGD11558 DsimGD11558 DsimGD11434 DsimGD11434 DsimGD11292 DsimGD11292 DsimGD11253 DsimGD11253 DsimGD23279 DsimGD23279
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD22283GD22283. (639 aa)
DsimGD24140GD24140. (194 aa)
DsimGD22386GD22386. (1001 aa)
DsimGD23110GD23110. (40 aa)
DsimGD22427GD22427. (196 aa)
DsimGD22428Receptor protein-tyrosine kinase. (1215 aa)
DsimGD23499GD23499. (786 aa)
DsimGD23022GD23022. (700 aa)
DsimGD23452GD23452. (554 aa)
DsimGD22052GD22052. (283 aa)
DsimGD24317GD24317. (299 aa)
DsimGD23817GD23817. (724 aa)
DsimGD14194GD14194. (108 aa)
DsimGD12853GD12853. (200 aa)
DsimGD21412GD21412. (239 aa)
DsimGD24573GD24573. (525 aa)
DsimGD24735GD24735. (429 aa)
DsimGD17149Bendless; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
DsimGD17456GD17456. (191 aa)
DsimGD16521GD16521; Belongs to the SKP1 family. (162 aa)
DsimGD17412GD17412; Belongs to the PDGF/VEGF growth factor family. (241 aa)
DsimGD16124GD16124. (87 aa)
DsimGD17230GD17230. (1625 aa)
DsimGD16235GD16235; Belongs to the protein kinase superfamily. (331 aa)
DsimGD16321GD16321. (235 aa)
Tak1Tak1; Belongs to the protein kinase superfamily. (451 aa)
DsimGD21040GD21040; Belongs to the DOCK family. (1466 aa)
DsimGD21039GD21039. (484 aa)
DsimGD18919GD18919. (570 aa)
DsimGD20464GD20464. (406 aa)
DsimGD21442GD21442. (374 aa)
DsimGD18469GD18469. (408 aa)
DsimGD18542LIM domain-containing protein. (348 aa)
DsimGD18063GD18063. (836 aa)
DsimGD19618GD19618. (1084 aa)
DsimGD18681RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
DsimGD18194GD18194. (1098 aa)
DsimGD18195GD18195. (212 aa)
DsimGD20154GD20154. (1621 aa)
DsimGD19320GD19320. (1336 aa)
DsimGD16381GD16381. (200 aa)
DsimGD13202GD13202. (145 aa)
DsimGD13332GD13332. (286 aa)
DsimGD13333GD13333. (361 aa)
DsimGD12346GD12346. (65 aa)
DsimGD13355Ubiquitin carboxyl-terminal hydrolase. (826 aa)
DsimGD13480GD13480. (535 aa)
DsimGD13487GD13487. (192 aa)
DsimGD13597GD13597. (621 aa)
DsimGD12518GD12518. (430 aa)
DsimGD13029GD13029. (1225 aa)
Urm1Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as Jafrac1, Ciao1, Eip71CD and GILT1. The thiocarboxylated form serves as substrate [...] (101 aa)
DsimGD12138E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (482 aa)
DsimGD13141GD13141. (993 aa)
Atg9Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (845 aa)
DsimGD10659Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (324 aa)
DsimGD11558F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
DsimGD11434Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (1165 aa)
DsimGD11292GD11292. (839 aa)
DsimGD11253GD11253. (114 aa)
DsimGD23279GD23279. (483 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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