(19 nodes) R3/R4 cell differentiation network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD16050	GD16050. (2427 aa)
	DsimGD16321	GD16321. (235 aa)
	N	Notch. (811 aa)
	pnt	Pnt. (354 aa)
	DsimGD18390	GD18390. (355 aa)
	DsimGD21289	GD21289. (2647 aa)
	Dl	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (823 aa)
	DsimGD18809	GD18809. (680 aa)
	DsimGD13571	GD13571. (199 aa)
	DsimGD15041	GD15041. (98 aa)
	DsimGD14489	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family. (415 aa)
	DsimGD25588	GD25588. (1329 aa)
	DsimGD11322	GD11322. (697 aa)
	DsimGD10750	GD10750; Belongs to the G-protein coupled receptor 2 family. (3463 aa)
	lola	GD25965. (671 aa)
	DsimGD25977	GD25977. (445 aa)
	DsimGD22871	GD22871. (716 aa)
	DsimGD24558	GD24558. (288 aa)
	DsimGD15385	GD15385. (289 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dl	N	B4QTE8	B4R3W6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch.	0.999
DsimGD10750	DsimGD14489	B4QAL9	B4QJZ3	GD10750; Belongs to the G-protein coupled receptor 2 family.	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	0.953
DsimGD11322	DsimGD18809	B4QBS0	B4QSY8	GD11322.	GD18809.	0.591
DsimGD13571	DsimGD18390	B4QLF2	B4R1F8	GD13571.	GD18390.	0.923
DsimGD13571	N	B4QLF2	B4R3W6	GD13571.	Notch.	0.426
DsimGD13571	pnt	B4QLF2	B4R1F9	GD13571.	Pnt.	0.478
DsimGD14489	DsimGD10750	B4QJZ3	B4QAL9	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	GD10750; Belongs to the G-protein coupled receptor 2 family.	0.953
DsimGD14489	N	B4QJZ3	B4R3W6	GD14489; Belongs to the G-protein coupled receptor Fz/Smo family.	Notch.	0.412
DsimGD15041	DsimGD16321	B4QL88	B4R469	GD15041.	GD16321.	0.406
DsimGD15385	DsimGD16050	B4NSC3	B4R761	GD15385.	GD16050.	0.784
DsimGD15385	DsimGD18390	B4NSC3	B4R1F8	GD15385.	GD18390.	0.574
DsimGD15385	DsimGD24558	B4NSC3	B4NU77	GD15385.	GD24558.	0.784
DsimGD15385	pnt	B4NSC3	B4R1F9	GD15385.	Pnt.	0.445
DsimGD16050	DsimGD15385	B4R761	B4NSC3	GD16050.	GD15385.	0.784
DsimGD16321	DsimGD15041	B4R469	B4QL88	GD16321.	GD15041.	0.406
DsimGD16321	DsimGD21289	B4R469	B4QWP1	GD16321.	GD21289.	0.406
DsimGD18390	DsimGD13571	B4R1F8	B4QLF2	GD18390.	GD13571.	0.923
DsimGD18390	DsimGD15385	B4R1F8	B4NSC3	GD18390.	GD15385.	0.574
DsimGD18390	DsimGD22871	B4R1F8	B4Q7N2	GD18390.	GD22871.	0.558
DsimGD18390	pnt	B4R1F8	B4R1F9	GD18390.	Pnt.	0.846