STRINGSTRING
DsimGD17754 DsimGD17754 R R Ras85D Ras85D DsimGD17456 DsimGD17456 DsimGD17412 DsimGD17412 DsimGD16951 DsimGD16951 DsimGD16875 DsimGD16875 DsimGD24822 DsimGD24822 DsimGD15725 DsimGD15725 DsimGD17261 DsimGD17261 DsimGD16699 DsimGD16699 N N DsimGD21034 DsimGD21034 DsimGD21033 DsimGD21033 tin tin DsimGD19422 DsimGD19422 DsimGD20937 DsimGD20937 DsimGD20936 DsimGD20936 DsimGD19895 DsimGD19895 DsimGD18513 DsimGD18513 DsimGD19064 DsimGD19064 DsimGD19065 DsimGD19065 DsimGD21343 DsimGD21343 DsimGD20793 DsimGD20793 DsimGD18690 DsimGD18690 spas spas DsimGD20048 DsimGD20048 DsimGD14871 DsimGD14871 DsimGD13487 DsimGD13487 DsimGD13056 DsimGD13056 DsimGD14008 DsimGD14008 DsimGD14938 DsimGD14938 DsimGD11720 DsimGD11720 DsimGD10058 DsimGD10058 DsimGD25109 DsimGD25109 DsimGD11158 DsimGD11158 DsimGD25590 DsimGD25590 DsimGD10610 DsimGD10610 DsimGD25232 DsimGD25232 DsimGD25233 DsimGD25233 DsimGD24926 DsimGD24926 DsimGD11837 DsimGD11837 DsimGD24979 DsimGD24979 DsimGD11802 DsimGD11802 DsimGD21801 DsimGD21801 DsimGD22284 DsimGD22284 DsimGD22289 DsimGD22289 DsimGD23617 DsimGD23617 DsimGD22349 DsimGD22349 DsimGD23607 DsimGD23607 DsimGD22909 DsimGD22909 DsimGD22403 DsimGD22403 DsimGD22427 DsimGD22427 DsimGD22428 DsimGD22428 DsimGD22511 DsimGD22511 DsimGD22512 DsimGD22512 DsimGD22513 DsimGD22513 DsimGD23402 DsimGD23402 DsimGD23401 DsimGD23401 DsimGD23341 DsimGD23341 DsimGD23340 DsimGD23340 DsimGD23309 DsimGD23309
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD17754GD17754. (57 aa)
RRoughened. (184 aa)
Ras85DRas-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. (189 aa)
DsimGD17456GD17456. (191 aa)
DsimGD17412GD17412; Belongs to the PDGF/VEGF growth factor family. (241 aa)
DsimGD16951GD16951. (331 aa)
DsimGD16875Integrin beta; Belongs to the integrin beta chain family. (838 aa)
DsimGD24822GD24822. (112 aa)
DsimGD15725GD15725; Belongs to the integrin alpha chain family. (1343 aa)
DsimGD17261GD17261. (376 aa)
DsimGD16699GD16699. (654 aa)
NNotch. (811 aa)
DsimGD21034GD21034. (257 aa)
DsimGD21033GD21033. (557 aa)
tinTin. (208 aa)
DsimGD19422GD19422. (116 aa)
DsimGD20937GD20937. (177 aa)
DsimGD20936GD20936; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
DsimGD19895GD19895. (582 aa)
DsimGD18513GD18513. (482 aa)
DsimGD19064GD19064. (696 aa)
DsimGD19065GD19065. (83 aa)
DsimGD21343GD21343. (184 aa)
DsimGD20793GD20793. (190 aa)
DsimGD18690GD18690. (723 aa)
spasSpastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (758 aa)
DsimGD20048GD20048; Belongs to the PI3/PI4-kinase family. (1079 aa)
DsimGD14871GD14871. (558 aa)
DsimGD13487GD13487. (192 aa)
DsimGD13056GD13056. (192 aa)
DsimGD14008GD14008; Belongs to the FPP/GGPP synthase family. (338 aa)
DsimGD14938GD14938. (1489 aa)
DsimGD11720GD11720. (239 aa)
DsimGD10058GD10058. (500 aa)
DsimGD25109GD25109. (1429 aa)
DsimGD11158GD11158. (192 aa)
DsimGD25590GD25590. (1506 aa)
DsimGD10610GD10610. (70 aa)
DsimGD25232GD25232. (536 aa)
DsimGD25233GD25233. (410 aa)
DsimGD24926GD24926. (536 aa)
DsimGD11837GD11837. (347 aa)
DsimGD24979GD24979. (596 aa)
DsimGD11802GD11802. (455 aa)
DsimGD21801GD21801. (534 aa)
DsimGD22284GD22284. (174 aa)
DsimGD22289Mitogen-activated protein kinase. (372 aa)
DsimGD23617GD23617. (430 aa)
DsimGD22349GD22349. (504 aa)
DsimGD23607GD23607. (556 aa)
DsimGD22909GD22909. (1405 aa)
DsimGD22403GD22403. (778 aa)
DsimGD22427GD22427. (196 aa)
DsimGD22428Receptor protein-tyrosine kinase. (1215 aa)
DsimGD22511GD22511. (405 aa)
DsimGD22512GD22512; Belongs to the PDGF/VEGF growth factor family. (477 aa)
DsimGD22513GD22513. (405 aa)
DsimGD23402GD23402. (784 aa)
DsimGD23401GD23401. (742 aa)
DsimGD23341GD23341. (581 aa)
DsimGD23340GD23340. (665 aa)
DsimGD23309GD23309. (326 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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