(54 nodes) Negative regulation of neurogenesis network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD15323	GD15323. (134 aa)
	DsimGD17722	GD17722. (152 aa)
	Dsimosa	Osa. (752 aa)
	DsimGD15194	GD15194. (119 aa)
	DsimGD24822	GD24822. (112 aa)
	DsimGD24871	GD24871. (203 aa)
	DsimGD20997	GD20997. (55 aa)
	DsimGD22576	GD22576. (433 aa)
	DsimGD22996	GD22996. (1161 aa)
	DsimGD23492	Serine/threonine-protein phosphatase. (309 aa)
	DsimGD23556	GD23556; Belongs to the semaphorin family. (897 aa)
	DsimGD22883	GD22883. (620 aa)
	DsimGD23607	GD23607. (556 aa)
	DsimGD21853	GD21853; Cadherins are calcium-dependent cell adhesion proteins. (1402 aa)
	DsimGD24188	GD24188. (547 aa)
	DsimGD24189	GD24189. (378 aa)
	DsimGD23268	GD23268. (1293 aa)
	DsimGD25452	GD25452; Belongs to the semaphorin family. (579 aa)
	DsimGD25375	GD25375. (310 aa)
	DsimGD25317	GD25317. (668 aa)
	DsimGD10624	GD10624. (474 aa)
	DsimGD11191	GD11191; Belongs to the semaphorin family. (784 aa)
	DsimGD11202	GD11202; Belongs to the semaphorin family. (697 aa)
	DsimGD14480	GD14480. (893 aa)
	DsimGD14481	GD14481. (78 aa)
	DsimGD12525	GD12525. (529 aa)
	DsimGD13607	GD13607. (612 aa)
	DsimGD12467	GD12467. (325 aa)
	DsimGD14703	GD14703. (398 aa)
	DsimGD13273	GD13273. (1328 aa)
	DsimGD12751	GD12751. (1097 aa)
	Rpd3	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (521 aa)
	DsimGD14871	GD14871. (558 aa)
	DsimGD19365	GD19365. (741 aa)
	DsimGD19364	GD19364. (1624 aa)
	Dl	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (823 aa)
	pros	Prospero. (623 aa)
	DsimGD18245	GD18245. (596 aa)
	DsimGD20218	GD20218. (640 aa)
	DsimGD20732	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (499 aa)
	DsimGD20735	GD20735. (682 aa)
	DsimGD19788	GD19788. (370 aa)
	DsimGD19615	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (438 aa)
	DsimGD20313	GD20313. (911 aa)
	DsimGD19499	GD19499. (233 aa)
	DsimGD20405	GD20405. (1320 aa)
	DsimGD20006	GD20006. (510 aa)
	DsimGD21513	GD21513. (911 aa)
	DsimGD16829	GD16829. (994 aa)
	DsimGD17039	GD17039. (1079 aa)
	DsimGD17040	GD17040. (150 aa)
	N	Notch. (811 aa)
	DsimGD15903	GD15903. (515 aa)
	DsimGD17439	GD17439. (88 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dl	DsimGD19364	B4QTE8	B4QS07	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GD19364.	0.647
Dl	DsimGD19365	B4QTE8	B4QS06	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	GD19365.	0.647
Dl	N	B4QTE8	B4R3W6	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch.	0.999
DsimGD11191	DsimGD23556	B4QHY5	B4Q780	GD11191; Belongs to the semaphorin family.	GD23556; Belongs to the semaphorin family.	0.747
DsimGD11202	DsimGD23556	B4QI01	B4Q780	GD11202; Belongs to the semaphorin family.	GD23556; Belongs to the semaphorin family.	0.801
DsimGD12467	DsimGD23268	B4QMT9	B4QA47	GD12467.	GD23268.	0.426
DsimGD12525	DsimGD15323	B4QLR7	B4NS20	GD12525.	GD15323.	0.852
DsimGD12525	DsimGD15903	B4QLR7	B4R428	GD12525.	GD15903.	0.950
DsimGD12525	DsimGD17722	B4QLR7	B4NSV5	GD12525.	GD17722.	0.771
DsimGD12525	DsimGD19615	B4QLR7	B4QWW2	GD12525.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.599
DsimGD12525	DsimGD19788	B4QLR7	B4QWW1	GD12525.	GD19788.	0.988
DsimGD12525	DsimGD20218	B4QLR7	B4QV51	GD12525.	GD20218.	0.852
DsimGD12525	DsimGD20313	B4QLR7	B4QXS1	GD12525.	GD20313.	0.957
DsimGD12525	Dsimosa	B4QLR7	B4NTD3	GD12525.	Osa.	0.852
DsimGD12525	Rpd3	B4QLR7	B4QR08	GD12525.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.599
DsimGD13273	DsimGD20006	B4QQI6	B4R143	GD13273.	GD20006.	0.930
DsimGD13607	DsimGD19364	B4QLZ8	B4QS07	GD13607.	GD19364.	0.494
DsimGD13607	DsimGD19365	B4QLZ8	B4QS06	GD13607.	GD19365.	0.494
DsimGD14480	DsimGD19364	B4QJK6	B4QS07	GD14480.	GD19364.	0.463
DsimGD14480	DsimGD19365	B4QJK6	B4QS06	GD14480.	GD19365.	0.463