STRINGSTRING
chic chic DsimGD17591 DsimGD17591 DsimGD24279 DsimGD24279 DsimGD17456 DsimGD17456 DsimGD15678 DsimGD15678 DsimGD17331 DsimGD17331 DsimGD15743 DsimGD15743 Dsim_GD17182 Dsim_GD17182 DsimGD15909 DsimGD15909 N N DsimGD15551 DsimGD15551 DsimGD15561 DsimGD15561 DsimGD15562 DsimGD15562 DsimGD18931 DsimGD18931 DsimGD20455 DsimGD20455 DsimGD19013 DsimGD19013 DsimGD19602 DsimGD19602 DsimGD13896 DsimGD13896 DsimGD14851 DsimGD14851 DsimGD14850 DsimGD14850 DsimGD12450 DsimGD12450 DsimGD12462 DsimGD12462 DsimGD13487 DsimGD13487 DsimGD13022 DsimGD13022 DsimGD11158 DsimGD11158 DsimGD25642 DsimGD25642 DsimGD11558 DsimGD11558 DsimGD25733 DsimGD25733 DsimGD25734 DsimGD25734 DsimGD11431 DsimGD11431 DsimGD17870 DsimGD17870 DsimGD24230 DsimGD24230 DsimGD23746 DsimGD23746 DsimGD23745 DsimGD23745 DsimGD21830 DsimGD21830 DsimGD17802 DsimGD17802 DsimGD22375 DsimGD22375 DsimGD23110 DsimGD23110 DsimGD22039 DsimGD22039
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chicProfilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (142 aa)
DsimGD17591GD17591; Belongs to the actin family. (180 aa)
DsimGD24279GD24279. (1090 aa)
DsimGD17456GD17456. (191 aa)
DsimGD15678GD15678. (351 aa)
DsimGD17331GD17331. (936 aa)
DsimGD15743Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (400 aa)
Dsim_GD17182Anon-381MEL; Belongs to the band 7/mec-2 family. Flotillin subfamily. (438 aa)
DsimGD15909GD15909. (1047 aa)
NNotch. (811 aa)
DsimGD15551GD15551. (201 aa)
DsimGD15561GD15561. (143 aa)
DsimGD15562GD15562. (348 aa)
DsimGD18931GD18931. (214 aa)
DsimGD20455GD20455. (473 aa)
DsimGD19013Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1243 aa)
DsimGD19602GD19602. (162 aa)
DsimGD13896GD13896. (2022 aa)
DsimGD14851GD14851. (2585 aa)
DsimGD14850GD14850. (1459 aa)
DsimGD12450GD12450. (399 aa)
DsimGD12462GD12462; Belongs to the histidine acid phosphatase family. (467 aa)
DsimGD13487GD13487. (192 aa)
DsimGD13022GD13022. (92 aa)
DsimGD11158GD11158. (192 aa)
DsimGD25642Protein kinase C. (580 aa)
DsimGD11558F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
DsimGD25733GD25733. (4046 aa)
DsimGD25734GD25734. (690 aa)
DsimGD11431GD11431. (684 aa)
DsimGD17870GD17870. (35 aa)
DsimGD24230GD24230. (2043 aa)
DsimGD23746GD23746. (332 aa)
DsimGD23745GD23745. (260 aa)
DsimGD21830GD21830. (2174 aa)
DsimGD17802GD17802. (61 aa)
DsimGD22375GD22375. (388 aa)
DsimGD23110GD23110. (40 aa)
DsimGD22039Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (377 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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