(60 nodes) Anatomical structure regression network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD13708	GD13708. (238 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (269 aa)
	DsimGD16015	GD16015. (121 aa)
	DsimGD16213	GD16213. (1161 aa)
	DsimGD17114	Kinase; Belongs to the inositol phosphokinase (IPK) family. (670 aa)
	DsimGD21513	GD21513. (911 aa)
	DsimGD17638	GD17638. (597 aa)
	DsimGD21467	GD21467; Belongs to the peptidase C14A family. (343 aa)
	DsimGD18486	GD18486. (370 aa)
	DsimGD18028	GD18028. (510 aa)
	DsimGD18541	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (522 aa)
	DsimGD19869	Non-specific serine/threonine protein kinase. (701 aa)
	DsimGD20854	GD20854; Belongs to the DEAD box helicase family. (784 aa)
	DsimGD20813	GD20813. (1345 aa)
	DsimGD19810	GD19810. (1342 aa)
	DsimGD19791	GD19791. (2837 aa)
	DsimGD19217	GD19217; Belongs to the LDH/MDH superfamily. (329 aa)
	DsimGD20610	GD20610. (433 aa)
	DsimGD21089	GD21089. (1474 aa)
	DsimGD21066	GD21066. (1100 aa)
	DsimGD18327	GD18327. (422 aa)
	DsimGD12695	GD12695; Belongs to the protein kinase superfamily. (261 aa)
	DsimGD12696	GD12696. (346 aa)
	DsimGD13891	GD13891. (1889 aa)
	DsimGD14854	GD14854. (1070 aa)
	DsimGD14832	GD14832. (640 aa)
	DsimGD14360	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (111 aa)
	DsimGD14791	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (481 aa)
	DsimGD12346	GD12346. (65 aa)
	DsimGD12350	GD12350. (410 aa)
	DsimGD12394	GD12394. (303 aa)
	DsimGD12395	GD12395. (928 aa)
	DsimGD14228	GD14228; Belongs to the peptidase C14A family. (449 aa)
	DsimGD13707	GD13707. (1656 aa)
	DsimGD13445	GD13445. (135 aa)
	DsimGD13447	GD13447. (938 aa)
	DsimGD14127	GD14127. (1393 aa)
	DsimGD13001	GD13001; Belongs to the BI1 family. (244 aa)
	Trap100	Trap100. (993 aa)
	DsimGD14059	GD14059. (435 aa)
	DsimGD11239	GD11239. (1421 aa)
	Atg9	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (845 aa)
	DsimGD10706	GD10706; Belongs to the AAA ATPase family. (801 aa)
	DsimGD10057	GD10057; Belongs to the ubiquitin-activating E1 family. (1191 aa)
	DsimGD25563	GD25563. (1432 aa)
	DsimGD10519	GD10519. (1310 aa)
	DsimGD25379	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (684 aa)
	DsimGD10334	GD10334. (882 aa)
	DsimGD10341	GD10341; Belongs to the peptidase C14A family. (160 aa)
	DsimGD10352	GD10352. (469 aa)
	DsimGD10849	GD10849; Belongs to the calmodulin family. (149 aa)
	DsimGD11777	Phosphatidylinositol 3-kinase catalytic subunit type 3. (949 aa)
	DsimGD22282	GD22282. (1136 aa)
	DsimGD22287	GD22287. (443 aa)
	Dif	Dif. (662 aa)
	DsimGD23096	Dynein light chain. (89 aa)
	DsimGD22996	GD22996. (1161 aa)
	DsimGD23862	GD23862; Belongs to the PI3/PI4-kinase family. (2168 aa)
	DsimGD24744	GD24744. (96 aa)
	DsimGD15194	GD15194. (119 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg5	Atg9	Q3MQ14	B4QHW9	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.864
Atg5	DsimGD10057	Q3MQ14	B4QHP5	Autophagy protein 5; Involved in autophagic vesicle formation.	GD10057; Belongs to the ubiquitin-activating E1 family.	0.744
Atg5	DsimGD11777	Q3MQ14	B4QAV9	Autophagy protein 5; Involved in autophagic vesicle formation.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.957
Atg5	DsimGD12695	Q3MQ14	B4QRR9	Autophagy protein 5; Involved in autophagic vesicle formation.	GD12695; Belongs to the protein kinase superfamily.	0.962
Atg5	DsimGD12696	Q3MQ14	B4QRR8	Autophagy protein 5; Involved in autophagic vesicle formation.	GD12696.	0.962
Atg5	DsimGD13707	Q3MQ14	B4QNL9	Autophagy protein 5; Involved in autophagic vesicle formation.	GD13707.	0.701
Atg5	DsimGD13708	Q3MQ14	B4QNM0	Autophagy protein 5; Involved in autophagic vesicle formation.	GD13708.	0.701
Atg5	DsimGD14059	Q3MQ14	B4QLJ4	Autophagy protein 5; Involved in autophagic vesicle formation.	GD14059.	0.967
Atg5	DsimGD14360	Q3MQ14	B4QR60	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
Atg5	DsimGD14854	Q3MQ14	B4QRG4	Autophagy protein 5; Involved in autophagic vesicle formation.	GD14854.	0.594
Atg5	DsimGD16015	Q3MQ14	B4R7M5	Autophagy protein 5; Involved in autophagic vesicle formation.	GD16015.	0.970
Atg5	DsimGD16213	Q3MQ14	B4R5C8	Autophagy protein 5; Involved in autophagic vesicle formation.	GD16213.	0.584
Atg5	DsimGD17638	Q3MQ14	B4R0T7	Autophagy protein 5; Involved in autophagic vesicle formation.	GD17638.	0.998
Atg5	DsimGD18327	Q3MQ14	B4QSF2	Autophagy protein 5; Involved in autophagic vesicle formation.	GD18327.	0.933
Atg5	DsimGD18541	Q3MQ14	B4QYL3	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.885
Atg5	DsimGD19810	Q3MQ14	B4QX05	Autophagy protein 5; Involved in autophagic vesicle formation.	GD19810.	0.901
Atg5	DsimGD20813	Q3MQ14	B4QX92	Autophagy protein 5; Involved in autophagic vesicle formation.	GD20813.	0.938
Atg5	DsimGD22287	Q3MQ14	B4Q8S0	Autophagy protein 5; Involved in autophagic vesicle formation.	GD22287.	0.587
Atg5	DsimGD23862	Q3MQ14	B4Q4A9	Autophagy protein 5; Involved in autophagic vesicle formation.	GD23862; Belongs to the PI3/PI4-kinase family.	0.561
Atg5	DsimGD25379	Q3MQ14	B4QD00	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.972