13 items (Drosophila simulans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD18346	GD18346. (424 aa)
	DsimGD15115	GD15115. (389 aa)
	DsimGD24583	GD24583. (548 aa)
	DsimGD21965	GD21965; Belongs to the cullin family. (1003 aa)
	DsimGD25803	GD25803. (700 aa)
	DsimGD25587	GD25587. (498 aa)
	DsimGD12552	GD12552; Belongs to the ubiquitin-conjugating enzyme family. (271 aa)
	DsimGD12518	GD12518. (430 aa)
	hyd	Hyd. (2749 aa)
	DsimGD20464	GD20464. (406 aa)
	DsimGD16376	GD16376. (397 aa)
	DsimGD17538	GD17538. (397 aa)
	DsimGD16872	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (376 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD12518	DsimGD16872	B4QLT4	B4R693	GD12518.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.441
DsimGD12518	DsimGD25587	B4QLT4	B4QH01	GD12518.	GD25587.	0.994
DsimGD12552	DsimGD16376	B4QL42	B4R3H1	GD12552; Belongs to the ubiquitin-conjugating enzyme family.	GD16376.	0.577
DsimGD12552	DsimGD17538	B4QL42	B4R3S2	GD12552; Belongs to the ubiquitin-conjugating enzyme family.	GD17538.	0.577
DsimGD12552	DsimGD21965	B4QL42	B4Q6D1	GD12552; Belongs to the ubiquitin-conjugating enzyme family.	GD21965; Belongs to the cullin family.	0.864
DsimGD15115	hyd	B4NT96	B4QWH5	GD15115.	Hyd.	0.802
DsimGD16376	DsimGD12552	B4R3H1	B4QL42	GD16376.	GD12552; Belongs to the ubiquitin-conjugating enzyme family.	0.577
DsimGD16376	DsimGD17538	B4R3H1	B4R3S2	GD16376.	GD17538.	0.900
DsimGD16872	DsimGD12518	B4R693	B4QLT4	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	GD12518.	0.441
DsimGD17538	DsimGD12552	B4R3S2	B4QL42	GD17538.	GD12552; Belongs to the ubiquitin-conjugating enzyme family.	0.577
DsimGD17538	DsimGD16376	B4R3S2	B4R3H1	GD17538.	GD16376.	0.900
DsimGD20464	DsimGD21965	B4R0J2	B4Q6D1	GD20464.	GD21965; Belongs to the cullin family.	0.999
DsimGD21965	DsimGD12552	B4Q6D1	B4QL42	GD21965; Belongs to the cullin family.	GD12552; Belongs to the ubiquitin-conjugating enzyme family.	0.864
DsimGD21965	DsimGD20464	B4Q6D1	B4R0J2	GD21965; Belongs to the cullin family.	GD20464.	0.999
DsimGD25587	DsimGD12518	B4QH01	B4QLT4	GD25587.	GD12518.	0.994
hyd	DsimGD15115	B4QWH5	B4NT96	Hyd.	GD15115.	0.802