(57 nodes) Dynein complex network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD20624	CG6971 protein. (250 aa)
	DsimGD15254	GD15254. (83 aa)
	DsimGD15397	Dynein light chain. (104 aa)
	DsimGD17567	GD17567. (451 aa)
	DsimGD15126	GD15126. (3064 aa)
	DsimGD15088	GD15088. (217 aa)
	DsimGD15077	GD15077. (390 aa)
	DsimGD24683	GD24683. (1183 aa)
	DsimGD24744	GD24744. (96 aa)
	DsimGD24507	GD24507. (105 aa)
	DsimGD22919	GD22919. (241 aa)
	DsimGD22061	GD22061. (565 aa)
	DsimGD21619	Dynein light chain roadblock. (97 aa)
	DsimGD24032	GD24032. (61 aa)
	DsimGD24033	GD24033. (182 aa)
	DsimGD23096	Dynein light chain. (89 aa)
	DsimGD23605	GD23605. (368 aa)
	DsimGD24114	GD24114. (281 aa)
	DsimGD24116	GD24116. (3288 aa)
	DsimGD22844	Dynein light chain roadblock. (97 aa)
	DsimGD21850	GD21850. (4107 aa)
	DsimGD25477	GD25477. (68 aa)
	DsimGD11269	Dynein light chain roadblock. (97 aa)
	DsimGD11860	GD11860. (130 aa)
	DsimGD10456	GD10456. (261 aa)
	DsimGD11487	GD11487. (111 aa)
	DsimGD10204	GD10204. (183 aa)
	DsimGD11552	GD11552. (739 aa)
	DsimGD10607	GD10607. (380 aa)
	DsimGD10079	GD10079. (188 aa)
	Lis-1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (411 aa)
	DsimGD11181	GD11181. (1215 aa)
	DsimGD12159	GD12159. (54 aa)
	DsimGD12150	GD12150. (929 aa)
	DsimGD13539	GD13539. (773 aa)
	DsimGD14027	GD14027. (1132 aa)
	DsimGD13620	Dynein light chain roadblock. (104 aa)
	DsimGD13451	GD13451. (685 aa)
	DsimGD13441	GD13441. (2891 aa)
	DsimGD12783	GD12783. (585 aa)
	DsimGD12274	GD12274. (1339 aa)
	DsimGD13229	GD13229. (2433 aa)
	DsimGD13231	GD13231. (848 aa)
	DsimGD13865	GD13865. (2700 aa)
	DsimGD13866	GD13866. (1642 aa)
	DsimGD19225	GD19225. (111 aa)
	DsimGD20745	GD20745. (173 aa)
	DsimGD20269	Dynein light chain roadblock. (101 aa)
	DsimGD20774	GD20774. (57 aa)
	DsimGD20775	GD20775. (4730 aa)
	DsimGD18081	GD18081. (598 aa)
	DsimGD21374	GD21374. (2951 aa)
	DsimGD20019	GD20019. (3194 aa)
	DsimGD20029	GD20029. (81 aa)
	DsimGD15550	GD15550. (167 aa)
	DsimGD16876	GD16876. (651 aa)
	DsimGD17381	GD17381. (330 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD10079	DsimGD11552	B4QH84	B4QFJ6	GD10079.	GD11552.	0.500
DsimGD10079	DsimGD12783	B4QH84	B4QQ99	GD10079.	GD12783.	0.471
DsimGD10079	DsimGD13441	B4QH84	B4QMK3	GD10079.	GD13441.	0.400
DsimGD10079	DsimGD13451	B4QH84	B4QMI8	GD10079.	GD13451.	0.724
DsimGD10079	DsimGD15088	B4QH84	B4NTE4	GD10079.	GD15088.	0.410
DsimGD10079	DsimGD16876	B4QH84	B4R6A3	GD10079.	GD16876.	0.453
DsimGD10079	DsimGD20019	B4QH84	B4R1N9	GD10079.	GD20019.	0.410
DsimGD10079	DsimGD20624	B4QH84	A0AN01	GD10079.	CG6971 protein.	0.599
DsimGD10079	DsimGD20775	B4QH84	B4QWI5	GD10079.	GD20775.	0.504
DsimGD10079	DsimGD22061	B4QH84	B4Q4T5	GD10079.	GD22061.	0.454
DsimGD10079	DsimGD23605	B4QH84	B4Q7S4	GD10079.	GD23605.	0.414
DsimGD10204	DsimGD11269	B4QF79	B4QAU0	GD10204.	Dynein light chain roadblock.	0.459
DsimGD10204	DsimGD11487	B4QF79	B4QEI7	GD10204.	GD11487.	0.475
DsimGD10204	DsimGD11860	B4QF79	B4QBZ7	GD10204.	GD11860.	0.459
DsimGD10204	DsimGD12783	B4QF79	B4QQ99	GD10204.	GD12783.	0.505
DsimGD10204	DsimGD15397	B4QF79	B4NSE9	GD10204.	Dynein light chain.	0.616
DsimGD10204	DsimGD15550	B4QF79	B4R2W5	GD10204.	GD15550.	0.400
DsimGD10204	DsimGD16876	B4QF79	B4R6A3	GD10204.	GD16876.	0.482
DsimGD10204	DsimGD17567	B4QF79	B4NT46	GD10204.	GD17567.	0.516
DsimGD10204	DsimGD19225	B4QF79	B4QUG3	GD10204.	GD19225.	0.750