(57 nodes) SH3 domain network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD24496	GD24496. (717 aa)
	DsimGD17441	GD17441. (104 aa)
	DsimGD15979	GD15979; Belongs to the glycosyltransferase 23 family. (251 aa)
	DsimGD21548	GD21548. (892 aa)
	DsimGD21039	GD21039. (484 aa)
	DsimGD19377	GD19377. (494 aa)
	DsimGD20012	GD20012. (549 aa)
	DsimGD20455	GD20455. (473 aa)
	DsimGD20929	GD20929. (958 aa)
	DsimGD18503	GD18503; Belongs to the MAGUK family. (769 aa)
	DsimGD18994	GD18994. (804 aa)
	DsimGD19022	GD19022. (1162 aa)
	DsimGD20836	GD20836. (1693 aa)
	DsimGD19128	GD19128. (711 aa)
	DsimGD20184	GD20184. (599 aa)
	DsimGD19255	GD19255. (369 aa)
	DsimGD18330	GD18330. (709 aa)
	Src64B	Tyrosine-protein kinase. (552 aa)
	DsimGD13264	GD13264. (631 aa)
	DsimGD14289	GD14289. (1071 aa)
	DsimGD13758	GD13758. (1393 aa)
	DsimGD12900	Sorting nexin; Belongs to the sorting nexin family. (565 aa)
	DsimGD14683	GD14683. (1028 aa)
	DsimGD13415	GD13415. (8412 aa)
	DsimGD12452	GD12452. (1421 aa)
	DsimGD14157	GD14157. (788 aa)
	DsimGD13438	GD13438. (2447 aa)
	DsimGD13501	GD13501. (812 aa)
	DsimGD13548	GD13548. (804 aa)
	DsimGD12654	GD12654. (531 aa)
	DsimGD10731	GD10731. (543 aa)
	DsimGD11119	GD11119. (997 aa)
	DsimGD11011	GD11011. (1064 aa)
	DsimGD25720	GD25720. (968 aa)
	DsimGD25733	GD25733. (4046 aa)
	drk	Drk. (182 aa)
	DsimGD25777	GD25777. (440 aa)
	DsimGD25329	GD25329. (320 aa)
	DsimGD10903	GD10903. (610 aa)
	DsimGD10390	Tyrosine-protein kinase. (517 aa)
	DsimGD24982	GD24982. (2043 aa)
	DsimGD11305	GD11305. (455 aa)
	DsimGD11292	GD11292. (839 aa)
	DsimGD25940	GD25940; Belongs to the MAGUK family. (377 aa)
	DsimGD24253	GD24253. (1134 aa)
	DsimGD22184	GD22184. (530 aa)
	DsimGD21733	GD21733. (1842 aa)
	DsimGD23740	GD23740. (690 aa)
	DsimGD23050	GD23050. (548 aa)
	DsimGD22424	Tyrosine-protein kinase. (621 aa)
	DsimGD21973	GD21973; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2167 aa)
	DsimGD23423	GD23423. (1454 aa)
	DsimGD21654	GD21654. (606 aa)
	DsimGD21680	GD21680; Belongs to the MAGUK family. (644 aa)
	DsimGD14194	GD14194. (108 aa)
	DsimGD24832	Phosphoinositide phospholipase C. (458 aa)
	DsimGD24498	GD24498. (275 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD10390	DsimGD13548	B4QCQ4	B4QKT2	Tyrosine-protein kinase.	GD13548.	0.727
DsimGD10390	DsimGD14194	B4QCQ4	B4NVQ7	Tyrosine-protein kinase.	GD14194.	0.662
DsimGD10390	DsimGD14683	B4QCQ4	B4QND4	Tyrosine-protein kinase.	GD14683.	0.557
DsimGD10390	DsimGD17441	B4QCQ4	B4R7P6	Tyrosine-protein kinase.	GD17441.	0.495
DsimGD10390	DsimGD18503	B4QCQ4	B4QZ93	Tyrosine-protein kinase.	GD18503; Belongs to the MAGUK family.	0.463
DsimGD10390	DsimGD22424	B4QCQ4	B4Q6C8	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.489
DsimGD10390	DsimGD23050	B4QCQ4	B4Q6K2	Tyrosine-protein kinase.	GD23050.	0.596
DsimGD10390	DsimGD24253	B4QCQ4	B4QAJ0	Tyrosine-protein kinase.	GD24253.	0.586
DsimGD10390	DsimGD24496	B4QCQ4	B4NUI0	Tyrosine-protein kinase.	GD24496.	0.464
DsimGD10390	DsimGD24832	B4QCQ4	B4NUI8	Tyrosine-protein kinase.	Phosphoinositide phospholipase C.	0.413
DsimGD10390	DsimGD24982	B4QCQ4	B4QBG7	Tyrosine-protein kinase.	GD24982.	0.580
DsimGD10390	Src64B	B4QCQ4	B4QR05	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.446
DsimGD10390	drk	B4QCQ4	B4QEE6	Tyrosine-protein kinase.	Drk.	0.702
DsimGD10903	DsimGD11011	B4QDD8	B4QEY9	GD10903.	GD11011.	0.779
DsimGD10903	DsimGD12654	B4QDD8	B4QJG1	GD10903.	GD12654.	0.738
DsimGD10903	DsimGD12900	B4QDD8	B4QNM9	GD10903.	Sorting nexin; Belongs to the sorting nexin family.	0.600
DsimGD10903	DsimGD13264	B4QDD8	B4QQK5	GD10903.	GD13264.	0.707
DsimGD10903	DsimGD14157	B4QDD8	B4QMQ6	GD10903.	GD14157.	0.538
DsimGD10903	DsimGD14289	B4QDD8	B4QPQ9	GD10903.	GD14289.	0.657
DsimGD10903	DsimGD19255	B4QDD8	B4QTX8	GD10903.	GD19255.	0.597