(36 nodes) Low-density lipoprotein (LDL) receptor class A repeat network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimGD12998	GD12998. (969 aa)
	DsimGD14152	GD14152; Belongs to the peptidase S1 family. (564 aa)
	DsimGD18173	GD18173. (190 aa)
	DsimGD16064	GD16064. (189 aa)
	DsimGD16065	GD16065. (1626 aa)
	DsimGD16890	GD16890. (671 aa)
	DsimGD17251	GD17251. (1704 aa)
	DsimGD15901	GD15901. (209 aa)
	DsimGD16362	GD16362. (3196 aa)
	DsimGD19936	GD19936. (447 aa)
	DsimGD19927	GD19927. (427 aa)
	DsimGD20271	GD20271; Belongs to the peptidase S1 family. (738 aa)
	DsimGD12285	GD12285. (1257 aa)
	DsimGD12256	GD12256. (594 aa)
	DsimGD12255	GD12255. (541 aa)
	DsimGD19292	GD19292. (223 aa)
	DsimGD21230	GD21230; Belongs to the G-protein coupled receptor 1 family. (769 aa)
	DsimGD18176	GD18176. (626 aa)
	DsimGD18175	GD18175. (332 aa)
	DsimGD18174	GD18174. (883 aa)
	DsimGD15368	GD15368. (1857 aa)
	DsimGD15249	GD15249. (68 aa)
	DsimGD17629	GD17629. (312 aa)
	DsimGD24659	GD24659. (838 aa)
	DsimGD20862	GD20862. (112 aa)
	DsimGD22519	GD22519. (2395 aa)
	Tep6	Thioester-containing protein 6. (1762 aa)
	DsimGD24077	GD24077. (577 aa)
	DsimGD23151	GD23151; Belongs to the peptidase S1 family. (690 aa)
	Dsim_GD23731	BcDNA:GH10711. (536 aa)
	DsimGD25759	GD25759. (1274 aa)
	DsimGD10549	GD10549. (174 aa)
	DsimGD25528	GD25528. (1326 aa)
	DsimGD12155	GD12155. (918 aa)
	DsimGD13121	GD13121. (2168 aa)
	DsimGD14459	GD14459. (2142 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD10549	DsimGD16362	B4QFP9	B4R3I9	GD10549.	GD16362.	0.406
DsimGD12155	DsimGD16890	B4QJ86	B4R6H3	GD12155.	GD16890.	0.511
DsimGD12255	DsimGD12256	B4QQX6	B4QQX5	GD12255.	GD12256.	0.989
DsimGD12255	DsimGD22519	B4QQX6	B4Q5B1	GD12255.	GD22519.	0.850
DsimGD12256	DsimGD12255	B4QQX5	B4QQX6	GD12256.	GD12255.	0.989
DsimGD12256	DsimGD22519	B4QQX5	B4Q5B1	GD12256.	GD22519.	0.846
DsimGD15249	DsimGD25528	B4NSE7	B4QI13	GD15249.	GD25528.	0.937
DsimGD15368	DsimGD16362	B4NS81	B4R3I9	GD15368.	GD16362.	0.406
DsimGD16064	DsimGD20862	B4R739	B4NVA0	GD16064.	GD20862.	0.479
DsimGD16362	DsimGD10549	B4R3I9	B4QFP9	GD16362.	GD10549.	0.406
DsimGD16362	DsimGD15368	B4R3I9	B4NS81	GD16362.	GD15368.	0.406
DsimGD16890	DsimGD12155	B4R6H3	B4QJ86	GD16890.	GD12155.	0.511
DsimGD18175	DsimGD18176	B4QVD8	B4QVD7	GD18175.	GD18176.	0.450
DsimGD18176	DsimGD18175	B4QVD7	B4QVD8	GD18176.	GD18175.	0.450
DsimGD20862	DsimGD16064	B4NVA0	B4R739	GD20862.	GD16064.	0.479
DsimGD21230	DsimGD25528	B4QVD0	B4QI13	GD21230; Belongs to the G-protein coupled receptor 1 family.	GD25528.	0.493
DsimGD22519	DsimGD12255	B4Q5B1	B4QQX6	GD22519.	GD12255.	0.850
DsimGD22519	DsimGD12256	B4Q5B1	B4QQX5	GD22519.	GD12256.	0.846
DsimGD25528	DsimGD15249	B4QI13	B4NSE7	GD25528.	GD15249.	0.937
DsimGD25528	DsimGD21230	B4QI13	B4QVD0	GD25528.	GD21230; Belongs to the G-protein coupled receptor 1 family.	0.493