(123 nodes) Homeobox-like domain superfamily network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DsimUbx	Ultrabithorax. (338 aa)
	DsimGD20268	GD20268. (631 aa)
	Abd-B	Abd-B. (519 aa)
	DsimGD17768	GD17768. (189 aa)
	DsimGD20718	GD20718. (487 aa)
	DsimGD19218	GD19218. (610 aa)
	DsimGD20190	GD20190. (782 aa)
	DsimGD19222	GD19222. (467 aa)
	DsimGD21183	GD21183. (713 aa)
	DsimGD21179	GD21179. (495 aa)
	pros	Prospero. (623 aa)
	DsimGD14861	Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. (808 aa)
	DsimGD14396	GD14396. (641 aa)
	DsimGD14390	GD14390. (687 aa)
	DsimGD14388	GD14388. (597 aa)
	DsimGD12719	GD12719. (666 aa)
	DsimGD12721	GD12721. (635 aa)
	DsimGD14373	GD14373. (642 aa)
	DsimGD12730	GD12730. (527 aa)
	DsimGD13784	GD13784. (278 aa)
	DsimGD13730	GD13730. (254 aa)
	DsimGD13728	GD13728. (359 aa)
	DsimGD14095	GD14095. (829 aa)
	DsimGD13495	GD13495. (1066 aa)
	DsimGD13499	GD13499. (452 aa)
	DsimGD13514	GD13514. (493 aa)
	DsimGD13515	GD13515. (524 aa)
	DsimGD13519	GD13519. (581 aa)
	DsimGD14043	GD14043. (321 aa)
	DsimGD12586	GD12586. (319 aa)
	DsimGD12614	GD12614. (644 aa)
	DsimGD13969	POU domain protein. (759 aa)
	DsimGD12122	GD12122. (367 aa)
	DsimGD12143	GD12143. (648 aa)
	DsimGD12161	GD12161. (392 aa)
	DsimGD25082	GD25082. (275 aa)
	DsimGD25155	GD25155. (275 aa)
	DsimGD25595	GD25595. (425 aa)
	DsimGD10643	GD10643. (479 aa)
	DsimGD10557	GD10557. (1046 aa)
	DsimGD25243	GD25243. (411 aa)
	DsimGD11547	GD11547. (903 aa)
	DsimGD25245	GD25245. (417 aa)
	DsimGD10533	GD10533. (292 aa)
	DsimGD11523	GD11523. (378 aa)
	DsimGD25709	GD25709. (814 aa)
	DsimGD10477	GD10477. (129 aa)
	DsimGD11439	GD11439. (751 aa)
	DsimGD10909	GD10909. (1001 aa)
	DsimGD24896	GD24896. (1038 aa)
	DsimGD11918	GD11918. (427 aa)
	DsimGD24898	GD24898. (449 aa)
	DsimGD25834	GD25834. (535 aa)
	DsimGD10352	GD10352. (469 aa)
	DsimGD11901	GD11901. (327 aa)
	en	Homeobox protein engrailed-like. (555 aa)
	DsimGD10802	Homeobox protein engrailed-like. (452 aa)
	DsimGD25001	GD25001. (220 aa)
	DsimGD10745	GD10745. (844 aa)
	DsimGD23773	GD23773. (304 aa)
	DsimGD21734	GD21734. (429 aa)
	DsimGD21780	GD21780. (438 aa)
	DsimGD22269	GD22269. (281 aa)
	DsimGD21801	GD21801. (534 aa)
	DsimGD22947	GD22947. (237 aa)
	DsimGD23036	GD23036. (355 aa)
	DsimGD23020	GD23020. (410 aa)
	DsimGD22979	GD22979. (297 aa)
	DsimGD22066	GD22066. (697 aa)
	DsimGD23847	POU domain protein. (889 aa)
	DsimGD23844	POU domain protein. (601 aa)
	DsimGD22610	GD22610. (417 aa)
	DsimGD22133	GD22133. (613 aa)
	DsimGD24280	GD24280. (440 aa)
	DsimGD24674	GD24674. (657 aa)
	DsimGD15259	GD15259. (111 aa)
	DsimGD17446	GD17446. (668 aa)
	DsimGD16514	GD16514. (723 aa)
	Lim1	Lim1. (345 aa)
	DsimGD15666	GD15666. (638 aa)
	DsimGD15668	GD15668. (547 aa)
	DsimGD16098	GD16098. (196 aa)
	oc	GD16101. (631 aa)
	DsimGD16852	GD16852. (1734 aa)
	DsimGD17261	GD17261. (376 aa)
	DsimGD16767	GD16767. (679 aa)
	DsimGD15807	POU domain protein. (266 aa)
	DsimGD16257	GD16257. (651 aa)
	DsimGD15920	GD15920. (1414 aa)
	DsimGD24421	GD24421. (680 aa)
	DsimGD24416	GD24416. (342 aa)
	ey	Eyeless. (429 aa)
	DsimGD24406	GD24406. (2054 aa)
	DsimGD21552	GD21552. (592 aa)
	DsimGD21545	GD21545. (1053 aa)
	DsimGD19379	GD19379. (198 aa)
	DsimGD20010	GD20010. (318 aa)
	DsimGD19422	GD19422. (116 aa)
	bap	Bap. (382 aa)
	DsimGD19977	GD19977. (412 aa)
	DsimGD19976	GD19976. (479 aa)
	DsimGD18444	GD18444. (158 aa)
	DsimGD20470	GD20470. (526 aa)
	DsimGD18937	GD18937. (496 aa)
	DsimGD19430	GD19430. (339 aa)
	DsimGD19974	GD19974. (658 aa)
	DsimGD19964	GD19964. (722 aa)
	DsimGD21441	GD21441. (514 aa)
	DsimGD20427	GD20427. (719 aa)
	DsimGD20912	GD20912. (1156 aa)
	DsimGD19515	GD19515. (374 aa)
	ftz	Ftz. (413 aa)
	DsimGD19518	GD19518. (463 aa)
	DsimGD19895	GD19895. (582 aa)
	bcd	Bicoid. (489 aa)
	DsimGD19522	GD19522. (351 aa)
	DsimGD19524	GD19524. (252 aa)
	DsimGD19525	GD19525. (789 aa)
	DsimGD20886	Transcriptional adapter. (421 aa)
	DsimGD19533	GD19533. (189 aa)
	DsimGD20313	GD20313. (911 aa)
	DsimGD19594	GD19594. (880 aa)
	DsimGD18113	GD18113. (345 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

Send network to Cytoscape

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abd-B	DsimGD13495	B4QWE8	B4QLX2	Abd-B.	GD13495.	0.507
Abd-B	DsimGD13499	B4QWE8	B4QLH9	Abd-B.	GD13499.	0.568
Abd-B	DsimGD17261	B4QWE8	B4R5K9	Abd-B.	GD17261.	0.997
Abd-B	DsimGD19515	B4QWE8	B4QYY1	Abd-B.	GD19515.	0.719
Abd-B	DsimGD19518	B4QWE8	B4QYX7	Abd-B.	GD19518.	0.435
Abd-B	DsimGD19895	B4QWE8	B4QYX5	Abd-B.	GD19895.	0.697
Abd-B	DsimGD20268	B4QWE8	B4QWF0	Abd-B.	GD20268.	0.727
Abd-B	DsimGD20718	B4QWE8	B4QV74	Abd-B.	GD20718.	0.839
Abd-B	DsimGD22979	B4QWE8	B4Q5N8	Abd-B.	GD22979.	0.453
Abd-B	DsimUbx	B4QWE8	B4QWF6	Abd-B.	Ultrabithorax.	0.746
Abd-B	ftz	B4QWE8	B4QYX9	Abd-B.	Ftz.	0.562
DsimGD10477	DsimGD12719	B4QE95	B4QRA5	GD10477.	GD12719.	0.602
DsimGD10477	DsimGD20718	B4QE95	B4QV74	GD10477.	GD20718.	0.531
DsimGD10477	DsimGD21183	B4QE95	B4QUC7	GD10477.	GD21183.	0.404
DsimGD10477	DsimGD24416	B4QE95	B4R2H8	GD10477.	GD24416.	0.532
DsimGD10477	DsimGD24421	B4QE95	B4R2I7	GD10477.	GD24421.	0.517
DsimGD10477	ey	B4QE95	B4R2G4	GD10477.	Eyeless.	0.643
DsimGD10477	oc	B4QE95	B4R6K6	GD10477.	GD16101.	0.423
DsimGD10533	DsimGD11547	B4QF90	B4QFI8	GD10533.	GD11547.	0.580
DsimGD10533	DsimGD11901	B4QF90	B4QCK9	GD10533.	GD11901.	0.417