(10 nodes) Transmembrane emp24 domain-containing protein network (Drosophila simulans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bai	Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity); Belongs to the EMP24/GP25L family. (206 aa)
	DsimGD15445	GD15445. (203 aa)
	DsimGD24531	GD24531. (79 aa)
	DsimGD21836	GD21836. (232 aa)
	DsimGD13935	GD13935. (237 aa)
	eca	Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization (By similarity). Belongs to the EMP24/GP25L family. (216 aa)
	DsimGD20000	GD20000. (352 aa)
	DsimGD15965	GD15965. (90 aa)
	DsimGD16693	GD16693. (208 aa)
	DsimGD15824	GD15824. (242 aa)

Your Current Organism:

Drosophila simulans

NCBI taxonomy Id: 7240
Other names: D. simulans

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DsimGD13935	DsimGD15445	B4QJ94	B4NSM6	GD13935.	GD15445.	0.412
DsimGD13935	DsimGD16693	B4QJ94	B4R4I4	GD13935.	GD16693.	0.484
DsimGD13935	bai	B4QJ94	A0AQ71	GD13935.	Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity); Belongs to the EMP24/GP25L family.	0.707
DsimGD13935	eca	B4QJ94	B4QWH9	GD13935.	Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization (By similarity). Belongs to the EMP24/GP25L family.	0.616
DsimGD15445	DsimGD13935	B4NSM6	B4QJ94	GD15445.	GD13935.	0.412
DsimGD15445	DsimGD15824	B4NSM6	B4R4X9	GD15445.	GD15824.	0.469
DsimGD15445	DsimGD15965	B4NSM6	B4R386	GD15445.	GD15965.	0.873
DsimGD15445	DsimGD20000	B4NSM6	B4R132	GD15445.	GD20000.	0.931
DsimGD15445	DsimGD24531	B4NSM6	B4NUB7	GD15445.	GD24531.	0.873
DsimGD15445	bai	B4NSM6	A0AQ71	GD15445.	Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity); Belongs to the EMP24/GP25L family.	0.989
DsimGD15445	eca	B4NSM6	B4QWH9	GD15445.	Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization (By similarity). Belongs to the EMP24/GP25L family.	0.957
DsimGD15824	DsimGD15445	B4R4X9	B4NSM6	GD15824.	GD15445.	0.469
DsimGD15824	DsimGD16693	B4R4X9	B4R4I4	GD15824.	GD16693.	0.469
DsimGD15824	DsimGD20000	B4R4X9	B4R132	GD15824.	GD20000.	0.491
DsimGD15824	bai	B4R4X9	A0AQ71	GD15824.	Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity); Belongs to the EMP24/GP25L family.	0.787
DsimGD15824	eca	B4R4X9	B4QWH9	GD15824.	Transmembrane emp24 domain-containing protein eca; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization (By similarity). Belongs to the EMP24/GP25L family.	0.624
DsimGD15965	DsimGD15445	B4R386	B4NSM6	GD15965.	GD15445.	0.873
DsimGD15965	DsimGD16693	B4R386	B4R4I4	GD15965.	GD16693.	0.873
DsimGD15965	DsimGD20000	B4R386	B4R132	GD15965.	GD20000.	0.816
DsimGD15965	bai	B4R386	A0AQ71	GD15965.	Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity); Belongs to the EMP24/GP25L family.	0.932