STRINGSTRING
DsimGD25873 DsimGD25873 DsimGD21666 DsimGD21666 DsimGD20828 DsimGD20828 DsimGD10216 DsimGD10216 DsimGD12014 DsimGD12014 DsimGD17588 DsimGD17588 DsimGD15188 DsimGD15188 DsimGD24729 DsimGD24729 DsimGD24595 DsimGD24595 DsimGD24428 DsimGD24428 DsimGD19047 DsimGD19047 DsimGD16019 DsimGD16019 DsimGD22663 DsimGD22663 DsimGD21651 DsimGD21651 DsimGD24309 DsimGD24309 DsimGD23876 DsimGD23876 DsimGD22535 DsimGD22535 DsimGD23929 DsimGD23929 DsimGD23492 DsimGD23492 DsimGD21944 DsimGD21944 DsimGD23530 DsimGD23530 DsimGD23542 DsimGD23542 DsimGD21927 DsimGD21927 DsimGD21913 DsimGD21913 DsimGD24065 DsimGD24065 DsimGD24066 DsimGD24066 DsimGD24069 DsimGD24069 DsimGD21900 DsimGD21900 DsimGD23595 DsimGD23595 DsimGD24120 DsimGD24120 DsimGD24137 DsimGD24137 DsimGD23166 DsimGD23166 DsimGD23168 DsimGD23168 DsimGD23664 DsimGD23664 DsimGD23696 DsimGD23696 DsimGD24178 DsimGD24178 DsimGD25961 DsimGD25961 DsimGD10758 DsimGD10758 DsimGD11263 DsimGD11263 DsimGD25016 DsimGD25016 DsimGD11854 DsimGD11854 DsimGD25861 DsimGD25861 DsimGD25859 DsimGD25859 DsimGD24914 DsimGD24914 DsimGD10317 DsimGD10317 DsimGD25330 DsimGD25330 DsimGD25785 DsimGD25785 DsimGD10952 DsimGD10952 DsimGD10243 DsimGD10243 DsimGD10970 DsimGD10970 DsimGD25748 DsimGD25748 DsimGD10516 DsimGD10516 DsimGD11553 DsimGD11553 DsimGD25662 DsimGD25662 DsimGD25618 DsimGD25618 DsimGD11667 DsimGD11667 DsimGD10678 DsimGD10678 DsimGD10047 DsimGD10047 DsimGD10046 DsimGD10046 DsimGD11207 DsimGD11207 DsimGD25072 DsimGD25072 DsimGD25066 DsimGD25066 DsimGD25046 DsimGD25046 DsimGD13171 DsimGD13171 DsimGD12683 DsimGD12683 DsimGD14970 DsimGD14970 DsimGD14518 DsimGD14518 DsimGD12587 DsimGD12587 DsimGD15002 DsimGD15002 DsimGD14084 DsimGD14084 DsimGD12971 DsimGD12971 DsimGD14135 DsimGD14135 DsimGD14646 DsimGD14646 DsimGD12455 DsimGD12455 DsimGD12452 DsimGD12452 aly aly DsimGD13314 DsimGD13314 DsimGD12771 DsimGD12771 DsimGD14340 DsimGD14340 Src64B Src64B Rpd3 Rpd3 DsimGD14381 DsimGD14381 DsimGD14837 DsimGD14837 DsimGD12199 DsimGD12199 DsimGD18834 DsimGD18834 DsimGD18337 DsimGD18337 DsimGD16600 DsimGD16600 DsimGD19321 DsimGD19321 DsimGD20675 DsimGD20675 DsimGD18709 DsimGD18709 DsimGD19685 DsimGD19685 DsimGD20732 DsimGD20732 DsimGD20762 DsimGD20762 DsimGD19639 DsimGD19639 DsimGD19625 DsimGD19625 DsimGD19821 DsimGD19821 DsimGD19074 DsimGD19074 DsimGD19061 DsimGD19061 DsimGD20327 DsimGD20327 DsimGD18528 DsimGD18528 DsimGD18526 DsimGD18526 DsimGD20882 DsimGD20882 DsimGD20884 DsimGD20884 DsimGD18995 DsimGD18995 DsimGD21420 DsimGD21420 DsimGD17842 DsimGD17842 DsimGD18456 DsimGD18456 DsimGD19968 DsimGD19968 DsimGD19970 DsimGD19970 DsimGD18940 DsimGD18940 DsimGD18438 DsimGD18438 DsimGD20482 DsimGD20482 DsimGD21012 DsimGD21012 DsimGD19371 DsimGD19371 DsimGD18359 DsimGD18359 DsimGD21035 DsimGD21035 DsimGD16958 DsimGD16958 DsimGD16439 DsimGD16439 hop hop DsimGD17469 DsimGD17469 DsimGD15982 DsimGD15982 DsimGD17527 DsimGD17527 DsimGD16344 DsimGD16344 DsimGD17106 DsimGD17106 DsimGD17109 DsimGD17109 Mcm3 Mcm3 DsimGD16723 DsimGD16723 DsimGD16236 DsimGD16236 DsimGD16756 DsimGD16756 DsimGD16758 DsimGD16758 DsimGD15773 DsimGD15773 DsimGD16810 DsimGD16810 DsimGD16811 DsimGD16811 DsimGD16141 DsimGD16141 DsimGD15658 DsimGD15658 DsimGD16521 DsimGD16521 DsimGD16459 DsimGD16459 Pros28.1B Pros28.1B Pros28.1A Pros28.1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD25873GD25873. (268 aa)
DsimGD21666CG9273 protein. (246 aa)
DsimGD20828Proteasome subunit beta. (205 aa)
DsimGD10216Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (244 aa)
DsimGD12014GD12014. (128 aa)
DsimGD17588GD17588. (155 aa)
DsimGD15188GD15188. (307 aa)
DsimGD24729GD24729. (894 aa)
DsimGD24595GD24595; Belongs to the protein kinase superfamily. (353 aa)
DsimGD24428GD24428. (283 aa)
DsimGD19047GD19047. (193 aa)
DsimGD16019Proteasome subunit beta. (206 aa)
DsimGD22663GD22663. (308 aa)
DsimGD21651GD21651. (371 aa)
DsimGD24309GD24309. (775 aa)
DsimGD23876Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (289 aa)
DsimGD22535Wee1-like protein kinase. (593 aa)
DsimGD23929GD23929. (460 aa)
DsimGD23492Serine/threonine-protein phosphatase. (309 aa)
DsimGD21944GD21944; Belongs to the cyclin family. (701 aa)
DsimGD23530GD23530. (590 aa)
DsimGD23542GD23542. (129 aa)
DsimGD21927GD21927. (426 aa)
DsimGD21913GD21913. (1707 aa)
DsimGD24065GD24065. (267 aa)
DsimGD24066GD24066. (73 aa)
DsimGD24069GD24069. (1318 aa)
DsimGD21900Proteasome subunit beta. (201 aa)
DsimGD23595Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (74 aa)
DsimGD24120Proteasome subunit beta. (279 aa)
DsimGD24137GD24137. (664 aa)
DsimGD23166Proteasome subunit beta. (211 aa)
DsimGD23168Proteasome subunit beta. (210 aa)
DsimGD23664Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (281 aa)
DsimGD23696GD23696. (156 aa)
DsimGD24178GD24178. (494 aa)
DsimGD25961CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (334 aa)
DsimGD10758Proteasome subunit beta. (282 aa)
DsimGD11263Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (244 aa)
DsimGD25016GD25016; Belongs to the SKP1 family. (160 aa)
DsimGD11854GD11854. (338 aa)
DsimGD25861GD25861; Belongs to the SKP1 family. (128 aa)
DsimGD25859GD25859; Belongs to the SKP1 family. (161 aa)
DsimGD24914GD24914. (567 aa)
DsimGD10317GD10317. (192 aa)
DsimGD25330GD25330. (267 aa)
DsimGD25785GD25785. (721 aa)
DsimGD10952Transcription factor. (383 aa)
DsimGD10243Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (536 aa)
DsimGD10970GD10970. (950 aa)
DsimGD25748GD25748. (719 aa)
DsimGD10516GD10516; Belongs to the cullin family. (774 aa)
DsimGD11553Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (264 aa)
DsimGD25662GD25662. (328 aa)
DsimGD25618GD25618. (737 aa)
DsimGD11667GD11667. (155 aa)
DsimGD10678GD10678. (243 aa)
DsimGD10047GD10047. (246 aa)
DsimGD10046Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (253 aa)
DsimGD11207GD11207; Belongs to the protein kinase superfamily. (317 aa)
DsimGD25072GD25072. (193 aa)
DsimGD25066GD25066. (114 aa)
DsimGD25046GD25046; Belongs to the SKP1 family. (170 aa)
DsimGD13171DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
DsimGD12683GD12683; Belongs to the cullin family. (660 aa)
DsimGD14970GD14970. (393 aa)
DsimGD14518Proteasome subunit beta. (272 aa)
DsimGD12587GD12587. (262 aa)
DsimGD15002GD15002; Belongs to the cyclin family. (324 aa)
DsimGD14084DNA primase; Belongs to the eukaryotic-type primase small subunit family. (438 aa)
DsimGD12971GD12971. (225 aa)
DsimGD14135DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (607 aa)
DsimGD14646GD14646. (264 aa)
DsimGD12455Proteasome subunit beta. (235 aa)
DsimGD12452GD12452. (1421 aa)
alyAly. (568 aa)
DsimGD13314GD13314. (300 aa)
DsimGD12771GD12771; Belongs to the cyclin family. (490 aa)
DsimGD14340GD14340; Belongs to the AAA ATPase family. (398 aa)
Src64BTyrosine-protein kinase. (552 aa)
Rpd3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (521 aa)
DsimGD14381GD14381. (212 aa)
DsimGD1483726S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (919 aa)
DsimGD12199DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (533 aa)
DsimGD18834Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
DsimGD18337GD18337; Belongs to the AAA ATPase family. (439 aa)
DsimGD16600Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (257 aa)
DsimGD19321GD19321. (855 aa)
DsimGD20675GD20675. (301 aa)
DsimGD18709DNA helicase; Belongs to the MCM family. (733 aa)
DsimGD19685GD19685. (557 aa)
DsimGD20732Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (499 aa)
DsimGD20762GD20762; Belongs to the AAA ATPase family. (389 aa)
DsimGD19639GD19639. (322 aa)
DsimGD19625Proteasome subunit beta; Belongs to the peptidase T1B family. (268 aa)
DsimGD19821GD19821. (483 aa)
DsimGD19074Non-specific serine/threonine protein kinase. (530 aa)
DsimGD19061GD19061. (779 aa)
DsimGD20327GD20327; Belongs to the MCM family. (883 aa)
DsimGD18528GD18528; Belongs to the MCM family. (311 aa)
DsimGD18526GD18526. (199 aa)
DsimGD20882Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (603 aa)
DsimGD20884GD20884. (268 aa)
DsimGD18995GD18995. (430 aa)
DsimGD21420Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (429 aa)
DsimGD17842GD17842. (479 aa)
DsimGD18456GD18456. (389 aa)
DsimGD19968DNA polymerase. (847 aa)
DsimGD19970GD19970. (796 aa)
DsimGD18940GD18940. (618 aa)
DsimGD18438GD18438. (695 aa)
DsimGD20482GD20482. (220 aa)
DsimGD21012DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2104 aa)
DsimGD19371GD19371; Belongs to the protein kinase superfamily. (314 aa)
DsimGD18359GD18359. (382 aa)
DsimGD21035GD21035; Belongs to the AAA ATPase family. (428 aa)
DsimGD16958GD16958; Belongs to the AAA ATPase family. (400 aa)
DsimGD16439GD16439. (575 aa)
hopHop. (524 aa)
DsimGD17469GD17469; Belongs to the SKP1 family. (157 aa)
DsimGD15982GD15982. (112 aa)
DsimGD17527GD17527; Belongs to the AAA ATPase family. (405 aa)
DsimGD16344GD16344; Belongs to the SKP1 family. (154 aa)
DsimGD17106GD17106. (504 aa)
DsimGD17109GD17109. (245 aa)
Mcm3Minichromosome maintenance 3. (264 aa)
DsimGD16723GD16723. (68 aa)
DsimGD16236GD16236. (155 aa)
DsimGD16756Proteasome subunit beta. (307 aa)
DsimGD16758GD16758. (236 aa)
DsimGD15773GD15773; Belongs to the cyclin family. (481 aa)
DsimGD16810GD16810. (187 aa)
DsimGD16811DNA helicase; Belongs to the MCM family. (817 aa)
DsimGD16141GD16141. (486 aa)
DsimGD15658GD15658. (911 aa)
DsimGD16521GD16521; Belongs to the SKP1 family. (162 aa)
DsimGD16459GD16459. (845 aa)
Pros28.1BProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (252 aa)
Pros28.1AProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (251 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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