STRINGSTRING
DsimGD16520 DsimGD16520 Pros28.1B Pros28.1B Pros28.1A Pros28.1A DsimGD17408 DsimGD17408 DsimGD20828 DsimGD20828 DsimGD10216 DsimGD10216 DsimGD12014 DsimGD12014 DsimGD15378 DsimGD15378 DsimGD15448 DsimGD15448 DsimGD17695 DsimGD17695 DsimGD24797 DsimGD24797 DsimGD24798 DsimGD24798 ci ci DsimGD19047 DsimGD19047 DsimGD13210 DsimGD13210 DsimGD16019 DsimGD16019 DsimGD22663 DsimGD22663 DsimGD23876 DsimGD23876 iHog iHog DsimGD23013 DsimGD23013 DsimGD21965 DsimGD21965 DsimGD21900 DsimGD21900 DsimGD23607 DsimGD23607 DsimGD21857 DsimGD21857 DsimGD24120 DsimGD24120 DsimGD22814 DsimGD22814 DsimGD23166 DsimGD23166 DsimGD23168 DsimGD23168 DsimGD23664 DsimGD23664 DsimGD23696 DsimGD23696 DsimGD24178 DsimGD24178 DsimGD10758 DsimGD10758 DsimGD11263 DsimGD11263 DsimGD11296 DsimGD11296 DsimGD11854 DsimGD11854 DsimGD25873 DsimGD25873 DsimGD10449 DsimGD10449 DsimGD25743 DsimGD25743 DsimGD11014 DsimGD11014 DsimGD11553 DsimGD11553 DsimGD25662 DsimGD25662 DsimGD10046 DsimGD10046 DsimGD25072 DsimGD25072 DsimGD25066 DsimGD25066 DsimGD14970 DsimGD14970 DsimGD14518 DsimGD14518 DsimGD12587 DsimGD12587 DsimGD14646 DsimGD14646 DsimGD12455 DsimGD12455 DsimGD13314 DsimGD13314 DsimGD14340 DsimGD14340 DsimGD14837 DsimGD14837 DsimGD20549 DsimGD20549 DsimGD18834 DsimGD18834 DsimGD18337 DsimGD18337 DsimGD16600 DsimGD16600 DsimGD21105 DsimGD21105 DsimGD20762 DsimGD20762 DsimGD19639 DsimGD19639 DsimGD19625 DsimGD19625 DsimGD20804 DsimGD20804 DsimGD18591 DsimGD18591 DsimGD19821 DsimGD19821 DsimGD21420 DsimGD21420 DsimGD18456 DsimGD18456 DsimGD20464 DsimGD20464 DsimGD20482 DsimGD20482 DsimGD18414 DsimGD18414 hh hh DsimGD18359 DsimGD18359 DsimGD21035 DsimGD21035 DsimGD16958 DsimGD16958 DsimGD16363 DsimGD16363 DsimGD17076 DsimGD17076 DsimGD17527 DsimGD17527 DsimGD17106 DsimGD17106 DsimGD16327 DsimGD16327 DsimGD17109 DsimGD17109 DsimGD16756 DsimGD16756 DsimGD17407 DsimGD17407
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DsimGD16520GD16520. (108 aa)
Pros28.1BProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (252 aa)
Pros28.1AProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (251 aa)
DsimGD17408GD17408. (240 aa)
DsimGD20828Proteasome subunit beta. (205 aa)
DsimGD10216Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (244 aa)
DsimGD12014GD12014. (128 aa)
DsimGD15378GD15378. (538 aa)
DsimGD15448GD15448. (417 aa)
DsimGD17695G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (444 aa)
DsimGD24797GD24797; Belongs to the protein kinase superfamily. (157 aa)
DsimGD24798GD24798. (100 aa)
ciCubitus interruptus, isoform A. (1402 aa)
DsimGD19047GD19047. (193 aa)
DsimGD13210GD13210. (318 aa)
DsimGD16019Proteasome subunit beta. (206 aa)
DsimGD22663GD22663. (308 aa)
DsimGD23876Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (289 aa)
iHogInterference hedgehog; Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc). Belongs to the immunoglobulin superfamily. IHOG family. (880 aa)
DsimGD23013GD23013; Belongs to the G-protein coupled receptor Fz/Smo family. (1034 aa)
DsimGD21965GD21965; Belongs to the cullin family. (1003 aa)
DsimGD21900Proteasome subunit beta. (201 aa)
DsimGD23607GD23607. (556 aa)
DsimGD21857GD21857. (452 aa)
DsimGD24120Proteasome subunit beta. (279 aa)
DsimGD22814GD22814; Belongs to the protein kinase superfamily. (319 aa)
DsimGD23166Proteasome subunit beta. (211 aa)
DsimGD23168Proteasome subunit beta. (210 aa)
DsimGD23664Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (281 aa)
DsimGD23696GD23696. (156 aa)
DsimGD24178GD24178. (494 aa)
DsimGD10758Proteasome subunit beta. (282 aa)
DsimGD11263Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (244 aa)
DsimGD11296GD11296. (1060 aa)
DsimGD11854GD11854. (338 aa)
DsimGD25873GD25873. (268 aa)
DsimGD10449GD10449. (143 aa)
DsimGD25743GD25743. (367 aa)
DsimGD11014GD11014. (122 aa)
DsimGD11553Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (264 aa)
DsimGD25662GD25662. (328 aa)
DsimGD10046Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (253 aa)
DsimGD25072GD25072. (193 aa)
DsimGD25066GD25066. (114 aa)
DsimGD14970GD14970. (393 aa)
DsimGD14518Proteasome subunit beta. (272 aa)
DsimGD12587GD12587. (262 aa)
DsimGD14646GD14646. (264 aa)
DsimGD12455Proteasome subunit beta. (235 aa)
DsimGD13314GD13314. (300 aa)
DsimGD14340GD14340; Belongs to the AAA ATPase family. (398 aa)
DsimGD1483726S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (919 aa)
DsimGD20549Suppressor of fused homolog. (478 aa)
DsimGD18834Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
DsimGD18337GD18337; Belongs to the AAA ATPase family. (439 aa)
DsimGD16600Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (257 aa)
DsimGD21105GD21105. (737 aa)
DsimGD20762GD20762; Belongs to the AAA ATPase family. (389 aa)
DsimGD19639GD19639. (322 aa)
DsimGD19625Proteasome subunit beta; Belongs to the peptidase T1B family. (268 aa)
DsimGD20804GD20804. (520 aa)
DsimGD18591GD18591. (538 aa)
DsimGD19821GD19821. (483 aa)
DsimGD21420Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (429 aa)
DsimGD18456GD18456. (389 aa)
DsimGD20464GD20464. (406 aa)
DsimGD20482GD20482. (220 aa)
DsimGD18414GD18414. (741 aa)
hhProtein hedgehog C-product; Intercellular signal essential for a variety of patterning events during development. Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks. Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc. In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu) (By similarity). The hedgehog protein C-product, which mediates the autocatalytic activity, [...] (395 aa)
DsimGD18359GD18359. (382 aa)
DsimGD21035GD21035; Belongs to the AAA ATPase family. (428 aa)
DsimGD16958GD16958; Belongs to the AAA ATPase family. (400 aa)
DsimGD16363GD16363. (998 aa)
DsimGD17076GD17076; Belongs to the protein kinase superfamily. (344 aa)
DsimGD17527GD17527; Belongs to the AAA ATPase family. (405 aa)
DsimGD17106GD17106. (504 aa)
DsimGD16327GD16327. (479 aa)
DsimGD17109GD17109. (245 aa)
DsimGD16756Proteasome subunit beta. (307 aa)
DsimGD17407GD17407. (172 aa)
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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