16 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ12309	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (613 aa)
	DvirGJ13293	Uncharacterized protein. (1095 aa)
	DvirGJ21473	ORC_WH_C domain-containing protein. (717 aa)
	DvirGJ20704	Uncharacterized protein. (188 aa)
	DvirGJ20070	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (923 aa)
	DvirGJ21075	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (456 aa)
	DvirGJ20481	Uncharacterized protein. (247 aa)
	DvirGJ19871	CDT1 domain-containing protein. (721 aa)
	DvirGJ17755	Protein kinase domain-containing protein. (643 aa)
	DvirGJ17814	Mcm10 domain-containing protein. (784 aa)
	DvirGJ17456	DBF4-type domain-containing protein. (1836 aa)
	mei-218	Mei-218. (954 aa)
	DvirGJ10914	MCM domain-containing protein; Belongs to the MCM family. (876 aa)
	DvirGJ16984	Protein kinase domain-containing protein. (749 aa)
	DvirGJ18148	AAA domain-containing protein. (460 aa)
	DvirGJ14342	Uncharacterized protein. (622 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ10914	DvirGJ12309	B4M4C7	B4LEL7	MCM domain-containing protein; Belongs to the MCM family.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.988
DvirGJ10914	DvirGJ13293	B4M4C7	B4LH34	MCM domain-containing protein; Belongs to the MCM family.	Uncharacterized protein.	0.881
DvirGJ10914	DvirGJ14342	B4M4C7	B4MB82	MCM domain-containing protein; Belongs to the MCM family.	Uncharacterized protein.	0.951
DvirGJ10914	DvirGJ16984	B4M4C7	B4M7G4	MCM domain-containing protein; Belongs to the MCM family.	Protein kinase domain-containing protein.	0.885
DvirGJ10914	DvirGJ17456	B4M4C7	B4LVM3	MCM domain-containing protein; Belongs to the MCM family.	DBF4-type domain-containing protein.	0.881
DvirGJ10914	DvirGJ17755	B4M4C7	B4LTA7	MCM domain-containing protein; Belongs to the MCM family.	Protein kinase domain-containing protein.	0.885
DvirGJ10914	DvirGJ17814	B4M4C7	B4LU06	MCM domain-containing protein; Belongs to the MCM family.	Mcm10 domain-containing protein.	0.978
DvirGJ10914	DvirGJ18148	B4M4C7	B4M8L6	MCM domain-containing protein; Belongs to the MCM family.	AAA domain-containing protein.	0.950
DvirGJ10914	DvirGJ19871	B4M4C7	B4LP18	MCM domain-containing protein; Belongs to the MCM family.	CDT1 domain-containing protein.	0.990
DvirGJ10914	DvirGJ20070	B4M4C7	B4LLD1	MCM domain-containing protein; Belongs to the MCM family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.981
DvirGJ10914	DvirGJ20481	B4M4C7	B4LNG3	MCM domain-containing protein; Belongs to the MCM family.	Uncharacterized protein.	0.895
DvirGJ10914	DvirGJ20704	B4M4C7	B4LKJ5	MCM domain-containing protein; Belongs to the MCM family.	Uncharacterized protein.	0.658
DvirGJ10914	DvirGJ21075	B4M4C7	B4LN60	MCM domain-containing protein; Belongs to the MCM family.	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.949
DvirGJ10914	DvirGJ21473	B4M4C7	B4LIX5	MCM domain-containing protein; Belongs to the MCM family.	ORC_WH_C domain-containing protein.	0.936
DvirGJ10914	mei-218	B4M4C7	B4M2D0	MCM domain-containing protein; Belongs to the MCM family.	Mei-218.	0.972
DvirGJ12309	DvirGJ10914	B4LEL7	B4M4C7	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	MCM domain-containing protein; Belongs to the MCM family.	0.988
DvirGJ12309	DvirGJ13293	B4LEL7	B4LH34	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Uncharacterized protein.	0.759
DvirGJ12309	DvirGJ14342	B4LEL7	B4MB82	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Uncharacterized protein.	0.998
DvirGJ12309	DvirGJ16984	B4LEL7	B4M7G4	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Protein kinase domain-containing protein.	0.822
DvirGJ12309	DvirGJ17456	B4LEL7	B4LVM3	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	DBF4-type domain-containing protein.	0.829