10 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ14169	Uncharacterized protein. (2693 aa)
	DvirGJ15244	Uncharacterized protein, isoform AA; Belongs to the MAGUK family. (1334 aa)
	DvirGJ25695	Uncharacterized protein, isoform A. (101 aa)
	DvirGJ12824	Uncharacterized protein. (192 aa)
	DvirGJ12990	Uncharacterized protein. (1515 aa)
	DvirGJ11188	Uncharacterized protein. (656 aa)
	Sur-8	Leucine-rich repeat protein soc-2 homolog; Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity). (614 aa)
	Nmdar1	Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation (By similarity). (984 aa)
	DvirGJ19244	Uncharacterized protein. (565 aa)
	DvirGJ15548	Uncharacterized protein. (902 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ12824	DvirGJ14169	B4LB86	A0A0Q9W070	Uncharacterized protein.	Uncharacterized protein.	0.522
DvirGJ12824	DvirGJ25695	B4LB86	A0A0Q9WB86	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.522
DvirGJ12824	Sur-8	B4LB86	B4LXW1	Uncharacterized protein.	Leucine-rich repeat protein soc-2 homolog; Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).	0.522
DvirGJ14169	DvirGJ12824	A0A0Q9W070	B4LB86	Uncharacterized protein.	Uncharacterized protein.	0.522
DvirGJ14169	DvirGJ15244	A0A0Q9W070	A0A0Q9W898	Uncharacterized protein.	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	0.631
DvirGJ14169	DvirGJ15548	A0A0Q9W070	B4MB33	Uncharacterized protein.	Uncharacterized protein.	0.408
DvirGJ14169	DvirGJ25695	A0A0Q9W070	A0A0Q9WB86	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.899
DvirGJ15244	DvirGJ14169	A0A0Q9W898	A0A0Q9W070	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	Uncharacterized protein.	0.631
DvirGJ15244	DvirGJ15548	A0A0Q9W898	B4MB33	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	Uncharacterized protein.	0.898
DvirGJ15244	DvirGJ25695	A0A0Q9W898	A0A0Q9WB86	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	Uncharacterized protein, isoform A.	0.631
DvirGJ15244	Nmdar1	A0A0Q9W898	B4LZB5	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation (By similarity).	0.944
DvirGJ15244	Sur-8	A0A0Q9W898	B4LXW1	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	Leucine-rich repeat protein soc-2 homolog; Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).	0.542
DvirGJ15548	DvirGJ14169	B4MB33	A0A0Q9W070	Uncharacterized protein.	Uncharacterized protein.	0.408
DvirGJ15548	DvirGJ15244	B4MB33	A0A0Q9W898	Uncharacterized protein.	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	0.898
DvirGJ15548	DvirGJ25695	B4MB33	A0A0Q9WB86	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.408
DvirGJ15548	Nmdar1	B4MB33	B4LZB5	Uncharacterized protein.	Glutamate [NMDA] receptor subunit 1; NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation (By similarity).	0.999
DvirGJ15548	Sur-8	B4MB33	B4LXW1	Uncharacterized protein.	Leucine-rich repeat protein soc-2 homolog; Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).	0.408
DvirGJ25695	DvirGJ12824	A0A0Q9WB86	B4LB86	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.522
DvirGJ25695	DvirGJ14169	A0A0Q9WB86	A0A0Q9W070	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.899
DvirGJ25695	DvirGJ15244	A0A0Q9WB86	A0A0Q9W898	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform AA; Belongs to the MAGUK family.	0.631