87 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ26732	Uncharacterized protein. (1317 aa)
	DvirGJ11519	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (546 aa)
	DvirGJ12441	Uncharacterized protein. (3587 aa)
	DvirGJ25971	Uncharacterized protein. (523 aa)
	DvirGJ20621	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
	DvirGJ12795	Uncharacterized protein, isoform B. (1594 aa)
	DvirGJ24191	Signal transducer and activator of transcription. (848 aa)
	DvirGJ23803	Uncharacterized protein, isoform B. (2254 aa)
	DvirGJ10901	Chloride channel protein. (1237 aa)
	DvirGJ18738	Uncharacterized protein, isoform U. (1952 aa)
	DvirGJ10553	Uncharacterized protein, isoform B. (839 aa)
	DvirGJ14885	Uncharacterized protein, isoform D. (1528 aa)
	DvirGJ16661	Uncharacterized protein, isoform B. (222 aa)
	DvirGJ11103	Uncharacterized protein, isoform C. (405 aa)
	DvirGJ14856	Uncharacterized protein. (691 aa)
	DvirGJ14767	ZP domain-containing protein. (673 aa)
	DvirGJ15618	FERM domain-containing protein. (638 aa)
	DvirGJ14356	Uncharacterized protein. (252 aa)
	DvirGJ19685	Uncharacterized protein, isoform C. (2593 aa)
	DvirGJ19783	Uncharacterized protein. (1443 aa)
	rst	Rst. (784 aa)
	kirre	Kirre, isoform A. (957 aa)
	DvirGJ15299	Uncharacterized protein. (2757 aa)
	DvirGJ12423	Uncharacterized protein. (865 aa)
	DvirGJ11223	Uncharacterized protein. (496 aa)
	DvirGJ13539	ZP domain-containing protein. (1440 aa)
	DvirGJ13033	Uncharacterized protein, isoform A. (1820 aa)
	DvirGJ13077	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (642 aa)
	DvirGJ11563	Uncharacterized protein, isoform A. (425 aa)
	DvirGJ12122	Uncharacterized protein, isoform A. (611 aa)
	DvirGJ13331	Uncharacterized protein. (533 aa)
	DvirGJ13948	Battenin. (425 aa)
	DvirGJ21467	Uncharacterized protein, isoform A. (842 aa)
	stau	Stau. (1063 aa)
	DvirGJ20186	Uncharacterized protein. (370 aa)
	DvirGJ20185	Uncharacterized protein. (316 aa)
	DvirGJ21632	Uncharacterized protein, isoform A. (324 aa)
	DvirGJ22222	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (3654 aa)
	DvirGJ20054	Receptor protein-tyrosine kinase. (1438 aa)
	DvirGJ21186	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (1170 aa)
	DvirGJ12986	Uncharacterized protein, isoform B. (4374 aa)
	DvirGJ21730	Uncharacterized protein, isoform B. (1229 aa)
	DvirGJ21853	Uncharacterized protein, isoform A. (1324 aa)
	DvirGJ22434	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	DvirGJ20358	Uncharacterized protein, isoform A; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
	DvirGJ21971	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (247 aa)
	DvirGJ11316	Uncharacterized protein, isoform A. (1914 aa)
	DvirGJ23889	Uncharacterized protein, isoform B. (1372 aa)
	DvirGJ16135	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (1426 aa)
	DvirGJ22924	Uncharacterized protein, isoform B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (526 aa)
	DvirGJ22000	Uncharacterized protein, isoform A. (1695 aa)
	DvirGJ15636	Lipase_GDSL domain-containing protein. (452 aa)
	DvirGJ15930	Uncharacterized protein, isoform A. (475 aa)
	Tep6	Thioester-containing protein 6. (1752 aa)
	DvirGJ11119	Ig-like domain-containing protein. (912 aa)
	DvirGJ17777	FERM domain-containing protein. (1547 aa)
	DvirGJ23579	Uncharacterized protein. (372 aa)
	DvirGJ23625	Uncharacterized protein, isoform A. (188 aa)
	DvirGJ22970	Uncharacterized protein, isoform C. (4104 aa)
	DvirGJ23722	Uncharacterized protein. (501 aa)
	DvirGJ23774	Uncharacterized protein. (1731 aa)
	DvirGJ23863	ABC transporter domain-containing protein. (777 aa)
	DvirGJ24577	Uncharacterized protein, isoform C. (1737 aa)
	DvirGJ23176	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1403 aa)
	DvirGJ23044	Uncharacterized protein, isoform A. (812 aa)
	DvirGJ18862	Uncharacterized protein. (4744 aa)
	DvirGJ19412	Uncharacterized protein; Belongs to the MAGUK family. (1977 aa)
	DvirGJ19473	Uncharacterized protein, isoform A. (201 aa)
	DvirGJ19132	Uncharacterized protein. (263 aa)
	DvirGJ10902	Chloride channel protein. (938 aa)
	DvirGJ10932	Uncharacterized protein, isoform A. (471 aa)
	DvirGJ10160	Uncharacterized protein. (652 aa)
	Kibra	Protein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...] (1276 aa)
	DvirGJ10709	Uncharacterized protein. (435 aa)
	DvirGJ10751	Uncharacterized protein. (129 aa)
	DvirGJ16478	Uncharacterized protein, isoform A. (961 aa)
	DvirGJ16423	Uncharacterized protein, isoform D. (875 aa)
	DvirGJ18055	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2504 aa)
	DvirGJ15793	Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (367 aa)
	DvirGJ15786	Uncharacterized protein. (1590 aa)
	DvirGJ15768	Uncharacterized protein. (1272 aa)
	DvirGJ15823	Uncharacterized protein. (356 aa)
	DvirGJ15708	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1256 aa)
	DVIR88_6g0056	Uncharacterized protein. (4581 aa)
	DvirGJ16071	Uncharacterized protein, isoform A. (2441 aa)
	DvirGJ15086	Uncharacterized protein, isoform A. (287 aa)
	DvirGJ19508	Uncharacterized protein. (2165 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ10160	DvirGJ13331	B4M4V5	B4LHN0	Uncharacterized protein.	Uncharacterized protein.	0.533
DvirGJ10160	DvirGJ15086	B4M4V5	B4MFP3	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.445
DvirGJ10160	DvirGJ23625	B4M4V5	B4LVZ0	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.564
DvirGJ10932	DvirGJ20054	B4M4G2	B4LLF8	Uncharacterized protein, isoform A.	Receptor protein-tyrosine kinase.	0.634
DvirGJ11103	DvirGJ19473	A0A0Q9W1U5	B4M2E0	Uncharacterized protein, isoform C.	Uncharacterized protein, isoform A.	0.874
DvirGJ11119	DvirGJ20054	B4LST1	B4LLF8	Ig-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.985
DvirGJ11316	kirre	B4LC26	B4MCT1	Uncharacterized protein, isoform A.	Kirre, isoform A.	0.657
DvirGJ11519	DvirGJ15299	A0A0Q9WKC6	B4MCT2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.954
DvirGJ11519	DvirGJ20054	A0A0Q9WKC6	B4LLF8	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Receptor protein-tyrosine kinase.	0.586
DvirGJ11519	DvirGJ23176	A0A0Q9WKC6	B4M0A6	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.411
DvirGJ12122	DvirGJ15793	B4LGI2	B4M9W2	Uncharacterized protein, isoform A.	Innexin; Structural component of the gap junctions. Belongs to the pannexin family.	0.458
DvirGJ12423	DvirGJ14885	B4LDF8	A0A0Q9W7V9	Uncharacterized protein.	Uncharacterized protein, isoform D.	0.478
DvirGJ12423	DvirGJ15823	B4LDF8	B4MA03	Uncharacterized protein.	Uncharacterized protein.	0.682
DvirGJ12423	DvirGJ19412	B4LDF8	B4M209	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.861
DvirGJ12423	DvirGJ19685	B4LDF8	B4MCK8	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.654
DvirGJ12423	DvirGJ20621	B4LDF8	A0A0Q9WFW4	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.791
DvirGJ12423	DvirGJ23803	B4LDF8	A0A0Q9WED9	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.900
DvirGJ12795	Kibra	A0A0Q9WFV7	B4M5X4	Uncharacterized protein, isoform B.	Protein kibra; Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signalin [...]	0.507
DvirGJ12986	DvirGJ15823	B4LDV2	B4MA03	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.463
DvirGJ12986	DvirGJ16071	B4LDV2	B4MGM3	Uncharacterized protein, isoform B.	Uncharacterized protein, isoform A.	0.958