(6 nodes) 5-flap endonuclease activity network (Drosophila virilis)

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Your Input:
	DvirGJ18024	Uncharacterized protein, isoform B. (1288 aa)
	DvirGJ23950	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (306 aa)
	DvirGJ20464	Uncharacterized protein. (646 aa)
	DvirGJ15173	AAA domain-containing protein. (1115 aa)
	Fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (386 aa)
	DvirGJ12207	Uncharacterized protein. (747 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ12207	DvirGJ15173	B4LFQ7	B4LQU0	Uncharacterized protein.	AAA domain-containing protein.	0.903
DvirGJ12207	DvirGJ18024	B4LFQ7	A0A0Q9W6E2	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.414
DvirGJ12207	DvirGJ20464	B4LFQ7	B4LSK1	Uncharacterized protein.	Uncharacterized protein.	0.791
DvirGJ12207	DvirGJ23950	B4LFQ7	B4LZ54	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.587
DvirGJ15173	DvirGJ12207	B4LQU0	B4LFQ7	AAA domain-containing protein.	Uncharacterized protein.	0.903
DvirGJ15173	DvirGJ18024	B4LQU0	A0A0Q9W6E2	AAA domain-containing protein.	Uncharacterized protein, isoform B.	0.847
DvirGJ15173	DvirGJ20464	B4LQU0	B4LSK1	AAA domain-containing protein.	Uncharacterized protein.	0.974
DvirGJ15173	DvirGJ23950	B4LQU0	B4LZ54	AAA domain-containing protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.809
DvirGJ15173	Fen1	B4LQU0	B4LM90	AAA domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.963
DvirGJ18024	DvirGJ12207	A0A0Q9W6E2	B4LFQ7	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.414
DvirGJ18024	DvirGJ15173	A0A0Q9W6E2	B4LQU0	Uncharacterized protein, isoform B.	AAA domain-containing protein.	0.847
DvirGJ18024	DvirGJ20464	A0A0Q9W6E2	B4LSK1	Uncharacterized protein, isoform B.	Uncharacterized protein.	0.545
DvirGJ18024	DvirGJ23950	A0A0Q9W6E2	B4LZ54	Uncharacterized protein, isoform B.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.773
DvirGJ18024	Fen1	A0A0Q9W6E2	B4LM90	Uncharacterized protein, isoform B.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.430
DvirGJ20464	DvirGJ12207	B4LSK1	B4LFQ7	Uncharacterized protein.	Uncharacterized protein.	0.791
DvirGJ20464	DvirGJ15173	B4LSK1	B4LQU0	Uncharacterized protein.	AAA domain-containing protein.	0.974
DvirGJ20464	DvirGJ18024	B4LSK1	A0A0Q9W6E2	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.545
DvirGJ20464	DvirGJ23950	B4LSK1	B4LZ54	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.829
DvirGJ20464	Fen1	B4LSK1	B4LM90	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.900
DvirGJ23950	DvirGJ12207	B4LZ54	B4LFQ7	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	Uncharacterized protein.	0.587