77 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ23199	Uncharacterized protein, isoform B. (430 aa)
	HP1D	Heterochromatin protein 1D, isoform A. (645 aa)
	DvirGJ21231	RING-type domain-containing protein. (1378 aa)
	DvirGJ21143	RING-type domain-containing protein. (1509 aa)
	DvirGJ20673	BTB domain-containing protein. (127 aa)
	DvirGJ22216	Uncharacterized protein. (1030 aa)
	DvirGJ20767	WASH_WAHD domain-containing protein. (521 aa)
	DvirGJ21530	Uncharacterized protein, isoform A; Belongs to the argonaute family. (989 aa)
	DvirGJ20897	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1722 aa)
	DvirGJ12080	Chromo domain-containing protein. (381 aa)
	Usp36	Ubiquitin carboxyl-terminal hydrolase 36; Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). Controls selective autophagy activation by ubiquitinated proteins; Belongs to the peptidase C19 family. (1214 aa)
	DvirGJ11550	SWIRM domain-containing protein. (900 aa)
	DvirGJ13188	Uncharacterized protein. (697 aa)
	DvirGJ13482	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (482 aa)
	DvirGJ11332	Uncharacterized protein, isoform A. (902 aa)
	DvirGJ11970	Non-specific serine/threonine protein kinase. (1268 aa)
	DvirGJ12430	Uncharacterized protein, isoform B. (519 aa)
	Trl	Trithorax-like, isoform D. (627 aa)
	DvirGJ10983	Uncharacterized protein, isoform B. (1281 aa)
	DvirGJ11699	Uncharacterized protein, isoform B. (746 aa)
	DvirGJ21743	Uncharacterized protein, isoform B; Belongs to the intermediate filament family. (641 aa)
	DvirGJ22014	Uncharacterized protein, isoform B. (1867 aa)
	DvirGJ26974	Uncharacterized protein, isoform B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (346 aa)
	DvirGJ17122	Uncharacterized protein. (1016 aa)
	DvirGJ14811	Uncharacterized protein, isoform C; Belongs to the PI3/PI4-kinase family. (2780 aa)
	DvirGJ21281	Uncharacterized protein, isoform B. (393 aa)
	DvirGJ13916	Uncharacterized protein; Belongs to the argonaute family. (863 aa)
	DvirGJ14585	Uncharacterized protein; Belongs to the argonaute family. (857 aa)
	HP1E	Heterochromatin protein 1E. (174 aa)
	HP1C	Heterochromatin protein 1C. (235 aa)
	DvirGJ23433	Uncharacterized protein. (362 aa)
	DvirGJ23830	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (149 aa)
	DvirGJ22802	Uncharacterized protein. (366 aa)
	DvirGJ23887	Histone acetyltransferase type B catalytic subunit. (456 aa)
	DvirGJ24563	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (436 aa)
	DvirGJ24607	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (2187 aa)
	DvirGJ24036	MRG domain-containing protein. (483 aa)
	DvirGJ24037	Uncharacterized protein, isoform A. (1150 aa)
	DvirGJ24041	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (644 aa)
	DvirGJ18830	Uncharacterized protein. (770 aa)
	DvirGJ18665	Uncharacterized protein, isoform A. (1505 aa)
	DvirGJ18664	Uncharacterized protein. (1182 aa)
	DvirGJ19163	Uncharacterized protein. (256 aa)
	DvirGJ10883	Uncharacterized protein, isoform A. (1315 aa)
	DvirGJ10281	Uncharacterized protein. (866 aa)
	DvirGJ11023	Uncharacterized protein. (548 aa)
	DvirGJ10059	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (336 aa)
	DvirGJ10686	RING-type domain-containing protein. (443 aa)
	DvirGJ10720	Uncharacterized protein. (663 aa)
	DvirGJ18099	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1445 aa)
	DvirGJ18023	CBFD_NFYB_HMF domain-containing protein. (130 aa)
	DvirGJ15764	SET domain-containing protein. (1122 aa)
	su(Hw)	Suppressor of hairy wing, isoform A. (900 aa)
	DvirGJ14213	Uncharacterized protein. (928 aa)
	DvirGJ14524	Uncharacterized protein. (934 aa)
	DvirGJ19772	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (356 aa)
	DvirGJ17920	Uncharacterized protein, isoform A. (1106 aa)
	DvirGJ18402	Uncharacterized protein. (1621 aa)
	Rpd3	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (527 aa)
	DvirGJ18513	Uncharacterized protein; Belongs to the peptidase C19 family. (1151 aa)
	DVIR88_6g0002	Uncharacterized protein. (518 aa)
	HP1A	Heterochromatin protein 1; Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression (By similarity). (213 aa)
	DvirGJ17385	BEN domain-containing protein. (394 aa)
	DvirGJ23385	Uncharacterized protein. (376 aa)
	DvirGJ17359	BEN domain-containing protein. (392 aa)
	DvirGJ19583	Uncharacterized protein; Belongs to the intermediate filament family. (623 aa)
	DvirGJ16866	Deacetylase sirtuin-type domain-containing protein. (883 aa)
	DvirGJ11132	Uncharacterized protein. (318 aa)
	DvirGJ20948	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (829 aa)
	DvirGJ17562	Uncharacterized protein. (227 aa)
	esc	Extra sexcombs. (425 aa)
	DvirGJ17469	WD_REPEATS_REGION domain-containing protein. (454 aa)
	HP1J	Heterochromatin protein 1J. (183 aa)
	calypso	Ubiquitin carboxyl-terminal hydrolase calypso; Polycomb group (PcG) protein. Catalytic component of the PR- DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-118' (H2AK118ub1). Does not deubiquitinate monoubiquitinated histone H2B. Required to maintain the transcriptionally repressive state of homeotic genes throughout development. The PR-DUB complex has weak or no activity toward 'Lys- 48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). Belongs to the peptidase C12 family. BAP1 subfamily. (462 aa)
	Kr	Kruppel. (542 aa)
	DvirGJ19895	Uncharacterized protein. (1298 aa)
	HP2	Heterochromatin protein 2, isoform C. (3078 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVIR88_6g0002	DvirGJ10983	D0Z777	A0A0Q9WK71	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.884
DVIR88_6g0002	DvirGJ11332	D0Z777	B4LBL2	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.443
DVIR88_6g0002	DvirGJ11699	D0Z777	A0A0Q9WIS5	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.496
DVIR88_6g0002	DvirGJ24563	D0Z777	B4LZC0	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.601
DVIR88_6g0002	Rpd3	D0Z777	B4MFY7	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.601
DVIR88_6g0002	calypso	D0Z777	B4LQ24	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase calypso; Polycomb group (PcG) protein. Catalytic component of the PR- DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-118' (H2AK118ub1). Does not deubiquitinate monoubiquitinated histone H2B. Required to maintain the transcriptionally repressive state of homeotic genes throughout development. The PR-DUB complex has weak or no activity toward 'Lys- 48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). Belongs to the peptidase C12 family. BAP1 subfamily.	0.564
DvirGJ10059	DvirGJ21530	B4M5C5	B4LJF3	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	Uncharacterized protein, isoform A; Belongs to the argonaute family.	0.590
DvirGJ10281	DvirGJ10686	B4M495	B4M620	Uncharacterized protein.	RING-type domain-containing protein.	0.947
DvirGJ10281	DvirGJ10983	B4M495	A0A0Q9WK71	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.820
DvirGJ10281	DvirGJ11332	B4M495	B4LBL2	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.783
DvirGJ10281	DvirGJ11699	B4M495	A0A0Q9WIS5	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.855
DvirGJ10281	DvirGJ12080	B4M495	B4LH19	Uncharacterized protein.	Chromo domain-containing protein.	0.919
DvirGJ10281	DvirGJ17469	B4M495	B4LQI2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.676
DvirGJ10281	DvirGJ18513	B4M495	B4MG84	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.514
DvirGJ10281	DvirGJ21143	B4M495	B4LM44	Uncharacterized protein.	RING-type domain-containing protein.	0.904
DvirGJ10281	DvirGJ21231	B4M495	B4LM45	Uncharacterized protein.	RING-type domain-containing protein.	0.903
DvirGJ10281	DvirGJ23199	B4M495	A0A0Q9WQW4	Uncharacterized protein.	Uncharacterized protein, isoform B.	0.718
DvirGJ10281	esc	B4M495	B4LQJ6	Uncharacterized protein.	Extra sexcombs.	0.734
DvirGJ10686	DvirGJ10281	B4M620	B4M495	RING-type domain-containing protein.	Uncharacterized protein.	0.947
DvirGJ10686	DvirGJ10983	B4M620	A0A0Q9WK71	RING-type domain-containing protein.	Uncharacterized protein, isoform B.	0.937