90 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vlc	Vlc, isoform C. (654 aa)
	DvirGJ15055	Uncharacterized protein, isoform I. (2238 aa)
	DvirGJ14169	Uncharacterized protein. (2693 aa)
	DvirGJ10104	Uncharacterized protein, isoform B. (1518 aa)
	DvirGJ16871	Uncharacterized protein, isoform B. (3026 aa)
	DvirGJ15244	Uncharacterized protein, isoform AA; Belongs to the MAGUK family. (1334 aa)
	DvirGJ14459	Uncharacterized protein, isoform F. (143 aa)
	DvirGJ20041	Uncharacterized protein, isoform B. (1337 aa)
	DvirGJ25695	Uncharacterized protein, isoform A. (101 aa)
	DvirGJ18748	Uncharacterized protein, isoform H. (1121 aa)
	DvirGJ18738	Uncharacterized protein, isoform U. (1952 aa)
	DvirGJ15641	Spectrin beta chain; Belongs to the spectrin family. (2308 aa)
	DvirGJ22950	Uncharacterized protein, isoform H. (770 aa)
	DvirGJ16887	Coronin; Belongs to the WD repeat coronin family. (1280 aa)
	DvirGJ22727	Uncharacterized protein, isoform P. (3636 aa)
	DvirGJ11972	Uncharacterized protein, isoform B. (634 aa)
	DvirGJ12042	Uncharacterized protein. (2049 aa)
	DvirGJ13828	Death domain-containing protein. (4880 aa)
	DvirGJ11519	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (546 aa)
	DvirGJ13827	Uncharacterized protein, isoform B. (1089 aa)
	DvirGJ18433	Uncharacterized protein, isoform F. (3497 aa)
	DvirGJ26245	Uncharacterized protein. (625 aa)
	DvirGJ26067	Uncharacterized protein. (2317 aa)
	DvirGJ17344	Uncharacterized protein, isoform K. (606 aa)
	DvirGJ18639	Uncharacterized protein, isoform E. (784 aa)
	DvirGJ12746	Uncharacterized protein, isoform B. (1077 aa)
	DvirGJ19675	Uncharacterized protein, isoform C. (662 aa)
	DvirGJ13712	Uncharacterized protein, isoform C. (2906 aa)
	DvirGJ11623	Uncharacterized protein, isoform B. (526 aa)
	DvirGJ12606	Tudor domain-containing protein. (233 aa)
	wls	Protein wntless; A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exos [...] (562 aa)
	DvirGJ12497	Protein kinase domain-containing protein. (807 aa)
	DvirGJ11261	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. (161 aa)
	DvirGJ11870	Uncharacterized protein, isoform A. (996 aa)
	DvirGJ11749	AH domain-containing protein. (414 aa)
	DvirGJ13689	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (785 aa)
	DvirGJ11577	Uncharacterized protein. (284 aa)
	DvirGJ22175	Uncharacterized protein. (213 aa)
	DvirGJ20694	Synaptogyrin. (239 aa)
	DvirGJ20081	Uncharacterized protein, isoform C. (1272 aa)
	DvirGJ22317	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (433 aa)
	Fsn	F-box/SPRY domain-containing protein 1; Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ); Belongs to the FBXO45/Fsn family. (252 aa)
	DvirGJ21795	Uncharacterized protein. (1175 aa)
	DvirGJ21322	Uncharacterized protein. (1848 aa)
	DvirGJ20472	Non-specific serine/threonine protein kinase. (1203 aa)
	DvirGJ22485	PX domain-containing protein. (401 aa)
	DvirGJ17518	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	DvirGJ15404	Uncharacterized protein, isoform A. (3480 aa)
	DvirGJ15540	Uncharacterized protein. (914 aa)
	DvirGJ15867	Uncharacterized protein. (372 aa)
	DvirGJ21312	COesterase domain-containing protein. (1217 aa)
	DvirGJ17756	Ig-like domain-containing protein. (588 aa)
	DvirGJ17758	Uncharacterized protein. (222 aa)
	DvirGJ17162	Uncharacterized protein, isoform A. (556 aa)
	DvirGJ17778	J domain-containing protein. (355 aa)
	DvirGJ17806	Uncharacterized protein, isoform A. (947 aa)
	DvirGJ17415	Uncharacterized protein, isoform A. (467 aa)
	nos	Nanos, isoform A; Belongs to the nanos family. (380 aa)
	DvirGJ24288	Uncharacterized protein. (900 aa)
	DvirGJ24289	Uncharacterized protein. (901 aa)
	DvirGJ22945	Uncharacterized protein, isoform C. (2454 aa)
	DvirGJ24340	Nicotinamide-nucleotide adenylyltransferase. (359 aa)
	DvirGJ23849	t-SNARE coiled-coil homology domain-containing protein. (394 aa)
	DvirGJ24523	WH2 domain-containing protein. (571 aa)
	DvirGJ23974	Fibroblast growth factor receptor. (737 aa)
	DvirGJ24601	Non-specific serine/threonine protein kinase. (705 aa)
	spas	Spastin; ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing. Belongs to the AAA ATPase family. Spastin subfamily. (769 aa)
	DvirGJ24132	Uncharacterized protein. (513 aa)
	DvirGJ24177	Uncharacterized protein. (572 aa)
	DvirGJ18812	Non-specific serine/threonine protein kinase. (876 aa)
	DvirGJ10932	Uncharacterized protein, isoform A. (471 aa)
	DvirGJ10948	Uncharacterized protein, isoform B; Belongs to the type-B carboxylesterase/lipase family. (1451 aa)
	DvirGJ10998	Rho-GAP domain-containing protein. (766 aa)
	DvirGJ16423	Uncharacterized protein, isoform D. (875 aa)
	DvirGJ15823	Uncharacterized protein. (356 aa)
	DvirGJ15864	Uncharacterized protein. (745 aa)
	DvirGJ15871	UDENN domain-containing protein. (2090 aa)
	DvirGJ15915	LLGL domain-containing protein. (1109 aa)
	DvirGJ14339	Uncharacterized protein. (1844 aa)
	DvirGJ14160	Uncharacterized protein, isoform D; Belongs to the MAGUK family. (906 aa)
	DvirGJ15230	Uncharacterized protein. (5756 aa)
	DvirGJ16232	Uncharacterized protein, isoform A. (697 aa)
	DvirGJ14758	Uncharacterized protein. (1023 aa)
	DvirGJ19847	Uncharacterized protein, isoform A. (629 aa)
	DvirGJ19213	Uncharacterized protein, isoform B. (1708 aa)
	DvirGJ15037	Uncharacterized protein, isoform D. (792 aa)
	DvirGJ15467	Uncharacterized protein, isoform A. (702 aa)
	DvirGJ16071	Uncharacterized protein, isoform A. (2441 aa)
	DVIR88_6g0054	Uncharacterized protein. (1632 aa)
	DVIR88_6g0043	Uncharacterized protein. (3494 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVIR88_6g0043	DvirGJ10932	D0Z7E8	B4M4G2	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.511
DVIR88_6g0043	DvirGJ14160	D0Z7E8	B4MC57	Uncharacterized protein.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.945
DVIR88_6g0043	DvirGJ14459	D0Z7E8	A0A0Q9W8W6	Uncharacterized protein.	Uncharacterized protein, isoform F.	0.655
DVIR88_6g0043	DvirGJ15055	D0Z7E8	A0A0Q9VYN2	Uncharacterized protein.	Uncharacterized protein, isoform I.	0.462
DVIR88_6g0043	DvirGJ15915	D0Z7E8	B4MAH5	Uncharacterized protein.	LLGL domain-containing protein.	0.433
DVIR88_6g0043	DvirGJ17415	D0Z7E8	B4LV77	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.763
DVIR88_6g0043	DvirGJ19675	D0Z7E8	A0A0Q9WWU4	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.580
DVIR88_6g0054	DvirGJ15641	D0Z7C6	A0A0Q9WDA0	Uncharacterized protein.	Spectrin beta chain; Belongs to the spectrin family.	0.649
DVIR88_6g0054	DvirGJ16071	D0Z7C6	B4MGM3	Uncharacterized protein.	Uncharacterized protein, isoform A.	0.496
DVIR88_6g0054	DvirGJ22945	D0Z7C6	B4LWM2	Uncharacterized protein.	Uncharacterized protein, isoform C.	0.456
DvirGJ10104	nos	A0A0Q9W1U3	B4LWF8	Uncharacterized protein, isoform B.	Nanos, isoform A; Belongs to the nanos family.	0.973
DvirGJ10932	DVIR88_6g0043	B4M4G2	D0Z7E8	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.511
DvirGJ10932	DvirGJ14160	B4M4G2	B4MC57	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.624
DvirGJ10932	DvirGJ15915	B4M4G2	B4MAH5	Uncharacterized protein, isoform A.	LLGL domain-containing protein.	0.443
DvirGJ10932	DvirGJ17415	B4M4G2	B4LV77	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.869
DvirGJ10932	DvirGJ18433	B4M4G2	A0A0Q9WL55	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform F.	0.511
DvirGJ10948	DvirGJ14160	B4M4J2	B4MC57	Uncharacterized protein, isoform B; Belongs to the type-B carboxylesterase/lipase family.	Uncharacterized protein, isoform D; Belongs to the MAGUK family.	0.497
DvirGJ10948	DvirGJ14339	B4M4J2	B4MB86	Uncharacterized protein, isoform B; Belongs to the type-B carboxylesterase/lipase family.	Uncharacterized protein.	0.749
DvirGJ11261	DvirGJ11577	B4LCQ7	B4LFP9	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis.	Uncharacterized protein.	0.981
DvirGJ11519	DvirGJ17415	A0A0Q9WKC6	B4LV77	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein, isoform A.	0.484