77 items (Drosophila virilis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DvirGJ23001	Uncharacterized protein, isoform B; Belongs to the AAA ATPase family. (404 aa)
	DvirGJ24297	Ubiquitin-like domain-containing protein. (118 aa)
	DvirGJ24517	AAA domain-containing protein; Belongs to the AAA ATPase family. (400 aa)
	DvirGJ23285	Uncharacterized protein. (566 aa)
	DvirGJ24070	AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
	DvirGJ22583	Uncharacterized protein, isoform A; Belongs to the AAA ATPase family. (428 aa)
	DvirGJ24151	AAA domain-containing protein; Belongs to the AAA ATPase family. (399 aa)
	DvirGJ24175	Uncharacterized protein. (2531 aa)
	DvirGJ19383	AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
	DvirGJ19166	Ubiquitin carboxyl-terminal hydrolase. (612 aa)
	DvirGJ10255	Uncharacterized protein, isoform A. (327 aa)
	DvirGJ10115	Uncharacterized protein. (3309 aa)
	DvirGJ15195	PI31_Prot_N domain-containing protein. (262 aa)
	DvirGJ14535	RING-type domain-containing protein. (679 aa)
	Fsn	F-box/SPRY domain-containing protein 1; Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ); Belongs to the FBXO45/Fsn family. (252 aa)
	DvirGJ20540	BZIP domain-containing protein. (537 aa)
	DvirGJ19858	Uncharacterized protein. (380 aa)
	DvirGJ21432	Uncharacterized protein. (857 aa)
	DvirGJ20343	Uncharacterized protein. (461 aa)
	DvirGJ21961	Uncharacterized protein. (2710 aa)
	DvirGJ21895	Uncharacterized protein, isoform A. (349 aa)
	DvirGJ14208	Uncharacterized protein. (1063 aa)
	DvirGJ14385	Uncharacterized protein, isoform A. (836 aa)
	DvirGJ15569	Uncharacterized protein. (119 aa)
	DvirGJ15572	AAA domain-containing protein; Belongs to the AAA ATPase family. (408 aa)
	DvirGJ15600	Uncharacterized protein, isoform A; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	DvirGJ15916	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa)
	DvirGJ15827	AAA domain-containing protein; Belongs to the AAA ATPase family. (397 aa)
	DvirGJ15825	RING-type domain-containing protein. (108 aa)
	DvirGJ17913	Uncharacterized protein; Belongs to the protein kinase superfamily. (353 aa)
	DvirGJ17972	DDA1 domain-containing protein. (107 aa)
	DvirGJ16380	WD_REPEATS_REGION domain-containing protein. (478 aa)
	DvirGJ16947	Uncharacterized protein, isoform A. (358 aa)
	DvirGJ16609	RBR-type E3 ubiquitin transferase. (507 aa)
	DvirGJ10363	CPSF_A domain-containing protein. (1140 aa)
	DvirGJ10774	Uncharacterized protein, isoform A. (746 aa)
	DvirGJ10484	Uncharacterized protein; Belongs to the protein kinase superfamily. (485 aa)
	DvirGJ10658	Uncharacterized protein, isoform A; Belongs to the protein kinase superfamily. (467 aa)
	DvirGJ10109	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	DvirGJ11840	Protein kinase domain-containing protein. (518 aa)
	DvirGJ11868	Uncharacterized protein. (471 aa)
	DvirGJ12467	Uncharacterized protein, isoform A. (846 aa)
	DvirGJ12273	Uncharacterized protein, isoform A. (962 aa)
	DvirGJ15436	Uncharacterized protein, isoform A; Belongs to the DEAD box helicase family. (403 aa)
	DvirGJ21401	Uncharacterized protein. (487 aa)
	DvirGJ13659	RBR-type E3 ubiquitin transferase. (485 aa)
	Usp36	Ubiquitin carboxyl-terminal hydrolase 36; Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4). Controls selective autophagy activation by ubiquitinated proteins; Belongs to the peptidase C19 family. (1214 aa)
	sina	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (314 aa)
	DvirGJ21209	Uncharacterized protein, isoform B; Belongs to the AAA ATPase family. (872 aa)
	DvirGJ26788	BTB domain-containing protein. (188 aa)
	DvirGJ11872	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1032 aa)
	DvirGJ18748	Uncharacterized protein, isoform H. (1121 aa)
	Oda	Ornithine decarboxylase antizyme. (273 aa)
	DvirGJ25832	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	DvirGJ12129	Uncharacterized protein. (673 aa)
	DvirGJ12074	Uncharacterized protein. (320 aa)
	DvirGJ20399	UBR-type domain-containing protein. (5355 aa)
	DvirGJ20039	LisH domain-containing protein. (851 aa)
	DvirGJ17695	Uncharacterized protein. (134 aa)
	DvirGJ10640	WD_REPEATS_REGION domain-containing protein. (529 aa)
	DvirGJ17774	Uncharacterized protein. (710 aa)
	DvirGJ17777	FERM domain-containing protein. (1547 aa)
	DvirGJ10286	Uncharacterized protein, isoform A. (643 aa)
	DvirGJ14230	CULLIN_2 domain-containing protein; Belongs to the cullin family. (756 aa)
	DvirGJ11302	Uncharacterized protein. (314 aa)
	DvirGJ15094	RBR-type E3 ubiquitin transferase. (518 aa)
	DvirGJ18358	Uncharacterized protein, isoform A. (270 aa)
	DvirGJ11488	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
	DvirGJ12705	Ubiquitin carboxyl-terminal hydrolase. (828 aa)
	DvirGJ11442	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (481 aa)
	DvirGJ21446	Uncharacterized protein. (261 aa)
	DvirGJ20228	CULLIN_2 domain-containing protein; Belongs to the cullin family. (821 aa)
	DvirGJ21567	Uncharacterized protein. (402 aa)
	DvirGJ22210	Uncharacterized protein. (1041 aa)
	DvirGJ20719	Uncharacterized protein. (556 aa)
	DvirGJ20127	RBR-type E3 ubiquitin transferase. (1187 aa)
	DvirGJ22283	Uncharacterized protein. (890 aa)

Your Current Organism:

Drosophila virilis

NCBI taxonomy Id: 7244
Other names: D. virilis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DvirGJ10109	DvirGJ10363	B4M545	B4M6L6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	CPSF_A domain-containing protein.	0.737
DvirGJ10109	DvirGJ11442	B4M545	B4LH99	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.499
DvirGJ10109	DvirGJ11488	B4M545	B4LGQ0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.649
DvirGJ10109	DvirGJ15600	B4M545	B4MAU1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein, isoform A; Belongs to the ubiquitin-conjugating enzyme family.	0.628
DvirGJ10109	DvirGJ15825	B4M545	B4MA07	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	RING-type domain-containing protein.	0.568
DvirGJ10109	DvirGJ20228	B4M545	B4LJM1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.685
DvirGJ10115	DvirGJ21961	B4M533	B4LR02	Uncharacterized protein.	Uncharacterized protein.	0.447
DvirGJ10255	DvirGJ10363	B4M4D8	B4M6L6	Uncharacterized protein, isoform A.	CPSF_A domain-containing protein.	0.954
DvirGJ10255	DvirGJ11302	B4M4D8	B4LC51	Uncharacterized protein, isoform A.	Uncharacterized protein.	0.408
DvirGJ10255	DvirGJ14230	B4M4D8	B4LUQ0	Uncharacterized protein, isoform A.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.932
DvirGJ10255	DvirGJ15572	B4M4D8	B4MAZ0	Uncharacterized protein, isoform A.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.626
DvirGJ10255	DvirGJ15825	B4M4D8	B4MA07	Uncharacterized protein, isoform A.	RING-type domain-containing protein.	0.774
DvirGJ10255	DvirGJ15827	B4M4D8	B4MA11	Uncharacterized protein, isoform A.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.822
DvirGJ10255	DvirGJ16947	B4M4D8	B4M792	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A.	0.489
DvirGJ10255	DvirGJ17972	B4M4D8	B4M974	Uncharacterized protein, isoform A.	DDA1 domain-containing protein.	0.570
DvirGJ10255	DvirGJ19383	B4M4D8	B4M1V5	Uncharacterized protein, isoform A.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.504
DvirGJ10255	DvirGJ20228	B4M4D8	B4LJM1	Uncharacterized protein, isoform A.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.974
DvirGJ10255	DvirGJ22583	B4M4D8	B4M0F9	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform A; Belongs to the AAA ATPase family.	0.648
DvirGJ10255	DvirGJ23001	B4M4D8	B4LVX6	Uncharacterized protein, isoform A.	Uncharacterized protein, isoform B; Belongs to the AAA ATPase family.	0.504
DvirGJ10255	DvirGJ24070	B4M4D8	B4M0C9	Uncharacterized protein, isoform A.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.780